Patents by Inventor Andrew Vila
Andrew Vila has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240024481Abstract: The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.Type: ApplicationFiled: October 3, 2023Publication date: January 25, 2024Inventors: Leo PAVLIV, Andrew VILA
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Patent number: 11806400Abstract: The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.Type: GrantFiled: May 7, 2020Date of Patent: November 7, 2023Assignee: Cumberland Pharmaceuticals Inc.Inventors: Leo Pavliv, Andrew Vila
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Publication number: 20220401360Abstract: Embodiments of the present invention include inhalable composition, comprising milrinone or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable carrier, an excipient, a surfactant; the composition being capable of being administered by inhalation.Type: ApplicationFiled: August 16, 2022Publication date: December 22, 2022Inventors: Nicholas A. Haglund, Zachary Cox, Leo Pavliv, Andrew Vila
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Publication number: 20220233473Abstract: A ready-to-administer stable injectable norepinephrine solution comprising water, norepinephrine, and a tonicity agent. The solution has a pH from 3.7 to 4.3 and is substantially free of chelating agents and antioxidants.Type: ApplicationFiled: January 26, 2022Publication date: July 28, 2022Applicant: Cumberland Pharmaceuticals Inc.Inventors: Leo PAVLIV, Andrew VILA
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Publication number: 20210106561Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.Type: ApplicationFiled: October 23, 2020Publication date: April 15, 2021Applicant: Cumberland Pharmaceuticals Inc.Inventors: Leo Pavliv, Andrew Vila
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Publication number: 20200316022Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.Type: ApplicationFiled: June 29, 2020Publication date: October 8, 2020Applicant: Cumberland Pharmaceuticals Inc.Inventors: Leo PAVLIV, Andrew Vila
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Publication number: 20200261581Abstract: The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.Type: ApplicationFiled: May 7, 2020Publication date: August 20, 2020Inventors: Leo PAVLIV, Andrew VILA
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Publication number: 20190142944Abstract: The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.Type: ApplicationFiled: January 16, 2019Publication date: May 16, 2019Inventors: Leo PAVLIV, Andrew VILA
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Publication number: 20190117621Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.Type: ApplicationFiled: December 21, 2018Publication date: April 25, 2019Applicant: Cumberland Pharmaceuticals Inc.Inventors: Leo PAVLIV, Andrew Vila
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Publication number: 20180344693Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.Type: ApplicationFiled: August 13, 2018Publication date: December 6, 2018Applicant: Cumberland Pharmaceuticals Inc.Inventors: Leo PAVLIV, Andrew Vila
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Publication number: 20180036282Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.Type: ApplicationFiled: October 20, 2017Publication date: February 8, 2018Applicant: Cumberland Pharmaceuticals Inc.Inventors: Leo Pavliv, Andrew Vila
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Publication number: 20180028440Abstract: Embodiments of the present invention include inhalable composition, comprising milrinone or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable carrier, an excipient, a surfactant; the composition being capable of being administered by inhalation.Type: ApplicationFiled: February 16, 2016Publication date: February 1, 2018Inventors: Nicholas A. Haglund, Zachary Cox, Leo Pavliv, Andrew Vila
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Patent number: 9820966Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.Type: GrantFiled: November 11, 2014Date of Patent: November 21, 2017Assignee: CUMBERLAND PHARMACEUTICALSInventors: Leo Pavliv, Andrew Vila
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Publication number: 20160128977Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.Type: ApplicationFiled: November 11, 2014Publication date: May 12, 2016Inventors: Leo PAVLIV, Andrew VILA
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Publication number: 20150335747Abstract: The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.Type: ApplicationFiled: June 30, 2015Publication date: November 26, 2015Inventors: Leo PAVLIV, Andrew VILA
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Patent number: 9072710Abstract: The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.Type: GrantFiled: March 16, 2012Date of Patent: July 7, 2015Assignee: Cumberland Pharmaceuticals Inc.Inventors: Leo Pavliv, Andrew Vila
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Patent number: 9072661Abstract: The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.Type: GrantFiled: March 16, 2012Date of Patent: July 7, 2015Assignee: Cumberland Pharmaceuticals Inc.Inventors: Leo Pavliv, Andrew Vila
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Publication number: 20150065553Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.Type: ApplicationFiled: November 11, 2014Publication date: March 5, 2015Inventors: Leo PAVLIV, Andrew VILA
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Patent number: 8933115Abstract: The present invention is directed to statin formulations having improved solubility and/or stability and methods for the same.Type: GrantFiled: January 22, 2013Date of Patent: January 13, 2015Assignee: Cumberland Pharmaceuticals Inc.Inventors: Leo Pavliv, Andrew Vila
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Publication number: 20130245120Abstract: The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from 100 mg/mL to 5 mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.Type: ApplicationFiled: March 16, 2012Publication date: September 19, 2013Applicant: Cumberland Pharmaceuticals Inc.Inventors: Leo Pavliv, Andrew Vila