Abstract: Systems and methods are provided for portable and compact nitric oxide (NO) generation that can be embedded into other therapeutic devices or used alone. In some embodiments, an ambulatory NO generation system can be comprised of a controller and disposable cartridge. The cartridge can contain filters and scavengers for preparing the gas used for NO generation and for scrubbing output gases prior to patient inhalation. The system can utilize an oxygen concentrator to increase nitric oxide production and compliment oxygen generator activity as an independent device. The system can also include a high voltage electrode assembly that is easily assembled and installed. Various nitric oxide delivery methods are provided, including the use of a nasal cannula.

Abstract: An exhaust pipe system for an articulated motor vehicle comprising at least a first part and a second part, the first and second parts being pivotable relative to one another, the exhaust pipe system comprising a first rigid portion securable to the first part of the vehicle; a second rigid portion securable to the second part of the vehicle; and an intermediate flexible portion connected at its ends to the rigid portions, the flexible portion comprising a coupling comprising two parts which are releasably secured together by fastening means to provide a substantially gas-tight seal between the two parts of the coupling, the fastening means being such that, when the two parts of the coupling are subjected to a force, relative to one another, above a predetermined level, the fastening means is released allowing the two parts of the coupling to separate from one another without damaging any of the exhaust pipe system.