Patents by Inventor Andrew W. Hannaman
Andrew W. Hannaman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11389531Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of an HBV vaccine to a subject. The disclosure comprises apparatus for the controlled administration of the HBV vaccine through an orifice to the subject, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.Type: GrantFiled: December 18, 2018Date of Patent: July 19, 2022Assignees: Janssen Sciences Ireland Unlimited Company, Ichor Medical Systems, Inc.Inventors: Daniel Boden, Helen Horton, Jean-Marc Edmond Fernand Marie Neefs, Soumitra Roy, Andrew W. Hannaman, Robert M. Bernard, Stephen A. Morse, Oliver Ruck, Adam Hartman, Thomas David Cox, Dorien De Pooter
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Publication number: 20220040478Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a subject. The present disclosure comprises apparatus for the controlled administration of the therapeutic agent through an orifice to the subject, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.Type: ApplicationFiled: October 26, 2021Publication date: February 10, 2022Inventors: Andrew W. Hannaman, Robert M. Bernard, Stephen A. Morse, Oliver Ruck, Adam Hartman, Thomas David Cox
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Patent number: 11185688Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a subject. The present disclosure comprises apparatus for the controlled administration of the therapeutic agent through an orifice to the subject, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.Type: GrantFiled: September 27, 2018Date of Patent: November 30, 2021Assignee: Ichor Medical Systems, Inc.Inventors: Andrew W. Hannaman, Robert M. Bernard, Stephen A. Morse, Oliver Ruck, Adam Hartman, Thomas David Cox
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Publication number: 20200139107Abstract: Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each electrode with a cross sectional area contributing to the total cross sectional area of all electrodes, and structural means incorporating an inanimate source of energy operatively connected to the plurality of electrodes for deploying the electrodes, wherein the source of energy is sufficient to impart a force of at least 1000 pounds per square inch (0.7 kilogram per square millimeter) of total cross sectional area of all electrodes at the initiation of the deployment of the electrodes. The apparatus will also comprise means for generating an electrical field which facilitates the intracellular delivery of a therapeutic agent, which means is operatively connected to said electrodes at least in their deployed state.Type: ApplicationFiled: January 8, 2020Publication date: May 7, 2020Inventors: Steven P. MASTERSON, Andrew W. HANNAMAN, Robert M. BERNARD
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Patent number: 10561834Abstract: Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each electrode with a cross sectional area contributing to the total cross sectional area of all electrodes, and structural means incorporating an inanimate source of energy operatively connected to the plurality of electrodes for deploying the electrodes, wherein the source of energy is sufficient to impart a force of at least 1000 pounds per square inch (0.7 kilogram per square millimeter) of total cross sectional area of all electrodes at the initiation of the deployment of the electrodes. The apparatus will also comprise means for generating an electrical field which facilitates the intracellular delivery of a therapeutic agent, which means is operatively connected to said electrodes at least in their deployed state.Type: GrantFiled: September 28, 2017Date of Patent: February 18, 2020Assignee: Ichor Medical Systems, Inc.Inventors: Steven P. Masterson, Andrew W. Hannaman, Robert M. Bernard
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Publication number: 20190184010Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of an HBV vaccine to a subject. The disclosure comprises apparatus for the controlled administration of the HBV vaccine through an orifice to the subject, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.Type: ApplicationFiled: December 18, 2018Publication date: June 20, 2019Inventors: Daniel Boden, Helen Horton, Jean-Marc Edmond Fernand Marie Neefs, Soumitra Roy, Andrew W. Hannaman, Robert M. Bernard, Stephen A. Morse, Oliver Ruck, Adam Hartman, Thomas David Cox
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Publication number: 20190175836Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a patient. The disclosure comprises means for the controlled administration of the therapeutic agent through an orifice to the patient, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and means for generating an electrical signal operatively connected to the electrodes.Type: ApplicationFiled: February 19, 2019Publication date: June 13, 2019Inventors: Robert M. BERNARD, Andrew W. HANNAMAN, Brady M. BERNARD
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Patent number: 10252004Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a patient. The invention comprises means for the controlled administration of the therapeutic agent through an orifice to the patient, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and means for generating an electrical signal operatively connected to the electrodes.Type: GrantFiled: November 14, 2016Date of Patent: April 9, 2019Assignee: Ichor Medical Systems, Inc.Inventors: Robert M. Bernard, Andrew W. Hannaman, Brady M. Bernard
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Publication number: 20190030329Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a subject. The present disclosure comprises apparatus for the controlled administration of the therapeutic agent through an orifice to the subject, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.Type: ApplicationFiled: September 27, 2018Publication date: January 31, 2019Inventors: Andrew W. HANNAMAN, Robert M. BERNARD, Stephen A. MORSE, Oliver RUCK, Adam HARTMAN, Thomas David COX
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Publication number: 20180272120Abstract: Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each electrode with a cross sectional area contributing to the total cross sectional area of all electrodes, and structural means incorporating an inanimate source of energy operatively connected to the plurality of electrodes for deploying the electrodes, wherein the source of energy is sufficient to impart a force of at least 1000 pounds per square inch (0.7 kilogram per square millimeter) of total cross sectional area of all electrodes at the initiation of the deployment of the electrodes. The apparatus will also comprise means for generating an electrical field which facilitates the intracellular delivery of a therapeutic agent, which means is operatively connected to said electrodes at least in their deployed state.Type: ApplicationFiled: September 28, 2017Publication date: September 27, 2018Inventors: Steven P. MASTERSON, Andrew W. HANNAMAN, Robert M. BERNARD
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Patent number: 9802035Abstract: Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each electrode with a cross sectional area contributing to the total cross sectional area of all electrodes, and structural means incorporating an inanimate source of energy operatively connected to the plurality of electrodes for deploying the electrodes, wherein the source of energy is sufficient to impart a force of at least 1000 pounds per square inch (0.7 kilogram per square millimeter) of total cross sectional area of all electrodes at the initiation of the deployment of the electrodes. The apparatus will also comprise means for generating an electrical field which facilitates the intracellular delivery of a therapeutic agent, which means is operatively connected to said electrodes at least in their deployed state.Type: GrantFiled: May 12, 2016Date of Patent: October 31, 2017Assignee: ICHOR MEDICAL SYSTEMS, INC.Inventors: Steven P. Masterson, Andrew W. Hannaman, Robert M. Bernard
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Publication number: 20170252515Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a patient. The invention comprises means for the controlled administration of the therapeutic agent through an orifice to the patient, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and means for generating an electrical signal operatively connected to the electrodes.Type: ApplicationFiled: November 14, 2016Publication date: September 7, 2017Inventors: Robert M. BERNARD, Andrew W. HANNAMAN, Brady M. BERNARD
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Publication number: 20170050015Abstract: Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to in a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each electrode with a cross sectional area contributing to the total cross sectional area of all electrodes, and structural means incorporating an inanimate source of energy operatively connected to the plurality of electrodes for deploying the electrodes, wherein the source of energy is sufficient to impart a force of at least 1000 pounds per square inch (0.7 kilogram per square millimeter) of total cross sectional area of all electrodes at the initiation of the deployment of the electrodes. The apparatus will also comprise means for generating an electrical field which facilitates the intracellular delivery of a therapeutic agent, which means is operatively connected to said electrodes at least in their deployed state.Type: ApplicationFiled: May 12, 2016Publication date: February 23, 2017Inventors: Steven P. MASTERSON, Andrew W. HANNAMAN, Robert M. BERNARD
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Patent number: 9526836Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a patient. The invention comprises means for the controlled administration of the therapeutic agent through an orifice to the patient, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and means for generating an electrical signal operatively connected to the electrodes.Type: GrantFiled: April 18, 2012Date of Patent: December 27, 2016Assignee: ICHOR MEDICAL SYSTEMS, INC.Inventors: Robert M. Bernard, Andrew W. Hannaman, Brady M. Bernard
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Patent number: 9364664Abstract: Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each electrode with a cross sectional area contributing to the total cross sectional area of all electrodes, and structural means incorporating an inanimate source of energy operatively connected to the plurality of electrodes for deploying the electrodes, wherein the source of energy is sufficient to impart a force of at least 1000 pounds per square inch (0.7 kilogram per square millimeter) of total cross sectional area of all electrodes at the initiation of the deployment of the electrodes. The apparatus will also comprise means for generating an electrical field which facilitates the intracellular delivery of a therapeutic agent, which means is operatively connected to said electrodes at least in their deployed state.Type: GrantFiled: March 8, 2005Date of Patent: June 14, 2016Assignee: ICHOR MEDICAL SYSTEMS, INC.Inventors: Steven P. Masterson, Andrew W. Hannaman, Robert M. Bernard
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Publication number: 20120277661Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a patient. The invention comprises means for the controlled administration of the therapeutic agent through an orifice to the patient, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and means for generating an electrical signal operatively connected to the electrodes.Type: ApplicationFiled: April 18, 2012Publication date: November 1, 2012Applicant: ICHOR MEDICAL SYSTEMS, INC.Inventors: Robert M. BERNARD, Andrew W. HANNAMAN, Brady M. BERNARD
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Patent number: 8187249Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a patient. The invention comprises means for the controlled administration of the therapeutic agent through an orifice to the patient, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and means for generating an electrical signal operatively connected to the electrodes.Type: GrantFiled: March 14, 2006Date of Patent: May 29, 2012Assignee: Ichor Medical Systems, Inc.Inventors: Robert M. Bernard, Andrew W. Hannaman, Brady M. Bernard
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Publication number: 20120078161Abstract: Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each electrode with a cross sectional area contributing to the total cross sectional area of all electrodes, and structural means incorporating an inanimate source of energy operatively connected to the plurality of electrodes for deploying the electrodes, wherein the source of energy is sufficient to impart a force of at least 1000 pounds per square inch (0.7 kilogram per square millimeter) of total cross sectional area of all electrodes at the initiation of the deployment of the electrodes. The apparatus will also comprise means for generating an electrical field which facilitates the intracellular delivery of a therapeutic agent, which means is operatively connected to said electrodes at least in their deployed state.Type: ApplicationFiled: March 8, 2005Publication date: March 29, 2012Inventors: Steven P. Masterson, Andrew W. Hannaman, Robert M. Bernard
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Patent number: 8108040Abstract: Method and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a patient. The invention comprises means for the controlled administration of the therapeutic agent (30) through an orifice to the patient, a plurality of penetrating electrodes (56) arranged with a predetermined spatial relationship relative to the orifice (14), and means for generating an electrical signal operatively connected to the electrodes.Type: GrantFiled: April 4, 2003Date of Patent: January 31, 2012Assignee: Ichor Medical Systems, Inc.Inventors: Robert M. Bernard, Andrew W. Hannaman, Brady M. Bernard, Steven P. Masterson
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Publication number: 20110288467Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of a therapeutic agent to a patient. The invention includes controlled administration of the therapeutic agent through an orifice to the patient, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.Type: ApplicationFiled: May 24, 2011Publication date: November 24, 2011Applicant: Ichor Medical Systems, Inc.Inventors: Robert M. Bernard, Andrew W. Hannaman, Brady M. Bernard, Steven P. Masterson