Abstract: A transcript of a call between a client and agent can be provided in real-time or near real-time and used to present links to relevant knowledge documents to the agent during the call. The call transcript can be automatically summarized and stored after the call.

Abstract: A combination comprising a Mcl-1 inhibitor and a second anticancer agent, wherein the second anticancer agent is selected from anthracyclines, cytarabine and hypomethylating agents, and compositions and uses thereof.

Abstract: A combination comprising a Mcl-1 inhibitor and a second anticancer agent, wherein the second anticancer agent is selected from anthracyclines, cytarabine and hypomethylating agents, and compositions and uses thereof.

Abstract: A combination comprising a BCL-2 inhibitor and a MCL1 inhibitor, and compositions and uses thereof.

Abstract: The present invention relates generally to therapeutic molecules useful for inducing apoptosis of particular cells such as, but not limited to, cancer cells and methods for generating and/or selecting same. The present invention further provides methods for inducing apoptosis of cells such as cancer cells and pharmaceutical compositions useful for same. The present invention further provides methods for generating or selecting therapeutic agents capable of inducing apoptosis of particular cells by the selective inhibition of pro-survival proteins. The present invention further provides a computational approach to therapeutic molecule design based on structure-binding characteristics.

Abstract: A method comprising enabling selection of interactivity control points of interest in media content; forwarding identification of at least one interactivity control point of interest to a wrapper generator; and attaching at least one script to the media content to monitor the at least one interactivity control point of interest when the media content is executed. The interactivity control points may include clickable points and mouse movement. The media content may include Flash media. The at least one script may be capable of monitoring all instances of consumer interaction with the interactivity control points occurring during media content playback. The method may also comprise generating configuration data for configuring the script to monitor only a portion of the instances of the consumer interaction with the interactivity control points occurring during media content playback.

Abstract: Conformationally constrained peptides that mimic BH3-only proteins and their conjugation to antibodies and other cell targeting compounds, compositions containing the conjugates and their use in the regulation of cell death are disclosed. The conformationally constrained peptides are capable of binding to and neutralising pro-survival Bcl-2 proteins. Processes for preparing the conformationally constrained peptides conjugated to antibodies and other cell targeting compounds and use of the conjugates in the treatment and/or prophylaxis of diseases or conditions associated with deregulation of cell death are also disclosed.