Patents by Inventor Andrew Welcher

Andrew Welcher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INTERFERON-LIKE PROTEINS AND USES THEREOF
    Publication number: 20120157666
    Abstract: The present invention provides Interferon-Like (IFN-L) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing IFN-L polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with IFN-L polypeptides.
    Type: Application
    Filed: February 14, 2012
    Publication date: June 21, 2012
    Inventors: ANDREW WELCHER, Duanzhi Wen, Michael Kelley
  • Interferon-like proteins and uses thereof
    Patent number: 8148109
    Abstract: The present invention provides Interferon-Like (IFN-L) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing IFN-L polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with IFN-L polypeptides.
    Type: Grant
    Filed: August 8, 2005
    Date of Patent: April 3, 2012
    Assignee: Amgen Inc.
    Inventors: Andrew Welcher, Duanzhi Wen, Michael Kelley
  • Interferon-like molecules and uses thereof
    Patent number: 7811791
    Abstract: The present invention provides Interferon-Like (IFN-L) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing IFN-L polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with IFN-L polypeptides.
    Type: Grant
    Filed: October 29, 2004
    Date of Patent: October 12, 2010
    Assignee: Amgen Inc.
    Inventors: Andrew Welcher, Duanzhi Wen, Michael Kelly
  • HUMAN ANTI-IFN-GAMMA NEUTRALIZING ANTIBODIES AS SELECTIVE IFN-GAMMA PATHWAY INHIBITORS
    Publication number: 20080107655
    Abstract: This invention provides antibodies that interact with or bind to human interferon-gamma (IFN-?) and methods for treating IFN-? mediated diseases by administering a pharmaceutically effective amount of antibodies to IFN-?. Methods of detecting the amount of IFN-? in a sample using antibodies to IFN-? are also provided.
    Type: Application
    Filed: December 21, 2007
    Publication date: May 8, 2008
    Applicants: Amgen Inc., Medarex, Inc.
    Inventors: Andrew Welcher, Hilary Chute, Yue-Sheng Li, Haichun Huang
  • C3b/C4b complement receptor-like molecules and uses thereof
    Publication number: 20060287502
    Abstract: Novel C3b/C4b CR-like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, selective binding agents, and methods for producing C3b/C4b CR-like polypeptides. Also provided for are methods for the treatment, diagnosis, amelioration, or prevention of diseases with C3b/C4b CR-like polypeptides.
    Type: Application
    Filed: May 5, 2006
    Publication date: December 21, 2006
    Applicant: AMGEN INC.
    Inventors: Andrew Welcher, Gary Elliott
  • EPH-like receptor protein tyrosine kinases
    Publication number: 20060216287
    Abstract: Four novel members of the EPH sub-family of receptor protein tyrosine kinases are disclosed. Nucleic acid sequences encoding receptor proteins, recombinant plasmids and host cells for expression, and methods of producing and using such receptors are also disclosed.
    Type: Application
    Filed: August 9, 2005
    Publication date: September 28, 2006
    Inventors: Gary Fox, Andrew Welcher, Shuqian Jing
  • B7-like molecules and uses thereof
    Publication number: 20060168672
    Abstract: Novel B7-like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, selective binding agents, and methods for producing B7-like polypeptides. Also provided for are methods for the treatment, diagnosis, amelioration, or prevention of diseases with B7-like polypeptides.
    Type: Application
    Filed: September 30, 2005
    Publication date: July 27, 2006
    Inventors: Andrew Welcher, Ulla Sarmiento, Henry Schultz, Hilary Chute
  • C3b/C4b complement receptor-like molecules and uses thereof
    Publication number: 20060030005
    Abstract: Novel C3b/C4b CR-like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, selective binding agents, and methods for producing C3b/C4b CR-like polypeptides. Also provided for are methods for the treatment, diagnosis, amelioration, or prevention of diseases with C3b/C4b CR-like polypeptides.
    Type: Application
    Filed: September 26, 2005
    Publication date: February 9, 2006
    Applicant: Amgen Inc.
    Inventors: Andrew Welcher, Gary Elliott
  • Interferon-Like molecules and uses thereof
    Publication number: 20060024795
    Abstract: The present invention provides Interferon-Like (IFN-L) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing IFN-L polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with IFN-L polypeptides.
    Type: Application
    Filed: August 8, 2005
    Publication date: February 2, 2006
    Inventors: Andrew Welcher, Duanzhi Wen, Michael Kelley
  • TNFr/OPG-like molecules and uses thereof
    Publication number: 20060024267
    Abstract: The present invention provides novel TNFr/OPG-like polypeptides and nucleic acid molecules encoding the same. The invention also provides vectors, host cells, antibodies, and methods for producing TNFr/OPG-like polypeptides. Also provided for are methods for the diagnosis and treatment of diseases with TNFr/OPG-like polypeptides.
    Type: Application
    Filed: January 25, 2005
    Publication date: February 2, 2006
    Inventors: Andrew Welcher, Gary Fox, Michael Boedigheimer, Junyan Shu, Shuqian Jing, Brian Bennett, Roland Luethy
  • Interferon-Like molecules and uses thereof
    Publication number: 20050221344
    Abstract: The present invention provides Interferon-Like (IFN-L) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing IFN-L polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with IFN-L polypeptides.
    Type: Application
    Filed: October 29, 2004
    Publication date: October 6, 2005
    Inventors: Andrew Welcher, Duanzhi Wen, Michael Kelley
  • Human anti-IFN-gamma neutralizing antibodies as selective IFN-gamma pathway inhibitors
    Publication number: 20050004353
    Abstract: This invention provides antibodies that interact with or bind to human interferon-gamma (IFN-?) and methods for treating IFN-? mediated diseases by administering a pharmaceutically effective amount of antibodies to IFN-?. Methods of detecting the amount of IFN-? in a sample using antibodies to IFN-? are also provided.
    Type: Application
    Filed: October 14, 2003
    Publication date: January 6, 2005
    Inventors: Andrew Welcher, Hilary Chute, Yue-Sheng "Luke" Li, Haichun Huang
  • Interferon-like molecules and uses thereof
    Publication number: 20020137137
    Abstract: The present invention provides Interferon-Like (IFN-L) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing IFN-L polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with IFN-L polypeptides.
    Type: Application
    Filed: August 10, 2001
    Publication date: September 26, 2002
    Applicant: Amgen, Inc.
    Inventors: Andrew Welcher, Duanzhi Wen, Michael Kelley
  • Peripheral myelin protein coding sequence and method
    Patent number: 5599920
    Abstract: The disclosed invention includes a a peripheral myelin protein, PMP-22, which is present predominantly in the peripheral nervous system and purified nucleic acids which encode the protein. Also included are oligonucleotide probes and primers derived from such sequences, and methods for the use of such sequences, probes and primers in detecting peripheral neuropathies.
    Type: Grant
    Filed: August 21, 1995
    Date of Patent: February 4, 1997
    Assignee: Baylor College of Medicine
    Inventors: Pragna I. Patel, Ueli Suter, G. Jackson Snipes, Andrew Welcher, Marino DeLeon, James R. Lupski, Eric M. Shooter