Abstract: The disclosure relates to USP30 Inhibitor Compounds, pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising same, and medical uses involving same.

Abstract: This disclosure relates generally to thermal management fluid systems. This disclosure relates more particularly to dielectric thermal management fluid systems useful in cooling electronic devices such as lithium-ion batteries, and methods of using such thermal management fluids.

Abstract: A method for activating a catalyst is described comprising the steps of: (i) installing a reduced and passivated catalyst containing crystallites of a catalytic metal comprising nickel, cobalt or iron in elemental form encapsulated by a layer comprising an oxide of the catalytic metal in a reactor, such as a steam methane reforming reactor, in which it is to be used, and (ii) heating the reduced and passivated catalyst in the reactor under a vacuum or an inert gas to a temperature in the range (TT?X) to (TT+Y), where TT is the Tammann temperature of the catalytic metal in elemental form in degrees Centigrade, X is 400 and Y is 200, to form a catalytically active surface on the catalyst without requiring the application of a reducing gas.

Abstract: Some embodiments relate to non-woven composite materials, methods of making and uses thereof, including articles including the composite structures. More particularly, some embodiments relates to non-woven composite materials possessing desirable impact performance and penetration resistance.

Abstract: Described herein are systems and methods for modeling complex outcomes using similarity and machine learning algorithms. Machine learning algorithms and models can be implemented on platforms comprising one or more user interfaces and an insight engine. In these embodiments, insight engine comprises a machine learning software algorithm (or module) configured to ingest data and generate insights.

Abstract: Systems for generating a USPTO office action response document based on an input USPTO Office Action document. A method implementation for constructing the USPTO office action response traverses a ruletree that has been dynamically formed from user answers to successive questions based on characteristics of the USPTO Office Action document. The ruletree comprises a first set of data items that pertains to an HCI and the ruletree further comprises a second set of data items that pertain to the target USPTO office action response document. Correspondence between the set of user answers to questions and passages in the USPTO office action response document are maintained in the ruletree. The ruletree expands and contracts during user interaction. To generate the USPTO office action response document, the ruletree is traversed in a sorted order, where traversal of a node generates a passage or passages in the generated USPTO office action response document.

Abstract: A transparent illumination system and related light guide plate is provided. The system is configured to facilitate total internal reflection propagation of light through the light guide plate despite low index of refraction differences between the glass material of the light guide layer and the adjacent layer. The system includes a light source, such as a laser diode, and an optical element to fan out light from the light source in the plane of the light guide plate. The light guide plate includes internal light extraction features.

Abstract: Systems for generating a USPTO office action response document based on an input USPTO Office Action document. A method implementation for constructing the USPTO office action response traverses a ruletree that has been dynamically formed from user answers to successive questions based on characteristics of the USPTO Office Action document. The ruletree comprises a first set of data items that pertains to an HCI and the ruletree further comprises a second set of data items that pertain to the target USPTO office action response document. Correspondence between the set of user answers to questions and passages in the USPTO office action response document are maintained in the ruletree. The ruletree expands and contracts during user interaction. To generate the USPTO office action response document, the ruletree is traversed in a sorted order, where traversal of a node generates a passage or passages in the generated USPTO office action response document.

Abstract: A display device that includes: a glass substrate comprising a refractive index (nsubstrate); a display device structure coupled to the substrate to collectively define a viewing area; and a black mask structure surrounding the display device structure that is coupled to the substrate and comprises a black ink layer and at least one glossy layer between the black ink layer and the glass substrate. The viewing area is characterized by (a) a reflectance from 0.5% to 2.5% as measured at 8 degrees from normal in the visible spectrum, (b) a brightness in the CIE colorimetry system such that 5<L*<17 for the specular component included (SCI), and (c) a brightness in the CIE colorimetry system such that 0<L*<3 for the specular component excluded (SCE). Further, the at least one glossy layer comprises a refractive index (nglossy) such that |nglossy?nsubstrate|>0.1.

Abstract: In one embodiment, an endpoint in a network sends a Session Initiation Protocol (SIP) registration request to a device. The device generates a first key using information included in the SIP registration request. The device also writes the first key to a storage location accessible by a Traversal Using Relays around Network address translators (TURN) server. The endpoint generates a second key based on the information included in the SIP registration request. The endpoint sends an allocate request to the TURN server that includes the second key. The TURN server authenticates the endpoint based in part by comparing the second key to the first key. The endpoint receives an allocate response from the TURN server, after the TURN server authenticates the endpoint.

Abstract: An apparatus includes first, second, and third glass portions, with the third glass portion between the first and the second, where the first, second, and third glass portions are configured in spaced relation from each other. The third glass portion is substantially parallel to the first glass portion. A light source emits light into the third glass portion via an edge of the third glass portion. Light-scattering structures scatter at least a portion of the light emitted by the light source into the third glass portion in a direction substantially perpendicular to a primary face of the third glass portion.

Abstract: In one embodiment, an endpoint in a network sends a Session Initiation Protocol (SIP) registration request to a device. The device generates a first key using information included in the SIP registration request. The device also writes the first key to a storage location accessible by a Traversal Using Relays around Network address translators (TURN) server. The endpoint generates a second key based on the information included in the SIP registration request. The endpoint sends an allocate request to the TURN server that includes the second key. The TURN server authenticates the endpoint based in part by comparing the second key to the first key. The endpoint receives an allocate response from the TURN server, after the TURN server authenticates the endpoint.

Abstract: A process for the extraction of one or more colour pigments from waste plastic in which a waste plastic feedstock is mixed with a solvent in a reactor having a shearing mechanism and the solvent is separated out and recycled in the process. The shearing mechanism provides high shear, high contact mixing so as to move the pigment to the surface of the plastic for contact with the solvent to give efficient colour pigment removal. Embodiments of reactors with shearing mechanisms are described. Environmentally friendly solvents are also described. The process gives highly sought after natural recyclate at a commercial scale.

Abstract: A transparent illumination system and related light guide plate is provided. The system is configured to facilitate total internal reflection propagation of light through the light guide plate despite low index of refraction differences between the glass material of the light guide layer and the adjacent layer. The system includes a light source, such as a laser diode, and an optical element to fan out light from the light source in the plane of the light guide plate. The light guide plate includes internal light extraction features.

Abstract: An apparatus and method for helically installing a vortex-induced vibration (VIV) suppression fin about a tubular. The apparatus may include an outer ring member dimensioned to encircle an underlying tubular and an inner ring member positioned concentrically inward from the outer ring member. The inner ring member is configured to rotate with respect to at least one of the outer ring member or the tubular as the outer ring member moves along the tubular. The apparatus may further include a fin guide configured to receive a fin and helically position the fin along the tubular as the inner ring member rotates. A method of installing a vortex-induced vibration (VIV) suppression fin about a tubular may include removably attaching a VIV suppression fin to an installation member. The installation member may be positioned along a tubular and moved about the tubular to helically position the fin around the tubular.

Abstract: A method for laser processing a transparent workpiece includes forming a contour line that includes defects, by directing a pulsed laser beam output by a beam source through an aspheric optical element positioned offset in a radial direction from the beam pathway and into the transparent workpiece such that the portion of the pulsed laser beam directed into the transparent workpiece generates an induced absorption within the transparent workpiece that produces a defect within the transparent workpiece. The portion of the pulsed laser beam directed into the transparent workpiece includes a wavelength ?, an effective spot size wo,eff, and a non-axisymmetric beam cross section having a minimum Rayleigh range ZRx,min in an x-direction and a minimum Rayleigh range ZRy,min in a y-direction. Further, the smaller of ZRx,min and ZRy,min is greater than F D = ? ? ? w 0 , eff 2 ? , where FD is a dimensionless divergence factor comprising a value of 10 or greater.

Abstract: Techniques for generating unregistered internet domain names using machine learning are presented. The techniques include parsing terms in an embedding training corpus of computer-readable text produce a tokenized embedding training corpus of text; adding tag(s) to produce a tagged tokenized embedding training corpus of text; vectorizing to produce a vector space embedding model mapping tagged tokenized terms to vectors; parsing domain names of a domain name training corpus of registered domain names to obtain a tokenized domain name training corpus; adding at least one tag to tokens to obtain a tagged tokenized domain name training corpus; vectorizing using the vector space model to produce a vectorized domain name training corpus; training a machine learning algorithm with the vectorized domain name training corpus to produce a trained machine learning model; generating an output domain name by the trained machine learning model; and outputting the output domain name.

Abstract: Disclosed herein are light guide plates (100, 100?, 100?) comprising a transparent substrate (110) having an edge surface (150), a light emitting first major surface (160), and an opposing second major surface (170); and a polymeric film (120) disposed on at least one of the first (160) and second (170) major surfaces of the transparent substrate, wherein the polymeric film (120) comprises a plurality of microstructures (130) and/or a plurality of light extraction features. At least one light source (140) may be coupled to the edge surface (150) of the transparent substrate (110). Display and lighting devices comprising such light guide plates are further disclosed, as well as methods for manufacturing such light guide plates.

Abstract: Embodiments are directed to systems for laser cutting at least one glass article comprising a pulsed laser assembly and a glass support assembly configured to support the glass article during laser cutting within the pulsed laser assembly, wherein the pulsed laser assembly comprises at least one non-diffracting beam (NDB) forming optical element configured to convert an input beam into a quasi-NDB beam; and at least one beam transforming element configured to convert the quasi-NDB beam into multiple quasi-NDB sub-beams spaced apart a distance of about 1 ?m to about 500 ?m; wherein the pulsed laser assembly is oriented to deliver one or more pulses of multiple quasi-NDB sub-beams onto a surface of the glass article, wherein each pulse of multiple quasi-NDB sub-beams is operable to cut a plurality of perforations in the glass article.

Abstract: A diffraction element can be employed in a surface display unit to provide diffraction peaks in a manner that reduces or eliminates a screen door effect that is prevalent in pixelated displays that does not have sufficient pixel density. The parameters of the diffraction element can be selected such that the diffraction peaks provide appearance of a larger pixel area than a corresponding physical pixel size. For example, first order diffraction peaks can be placed at a distance of about ? of a nearest subpixel-to-sub-pixel distance. The surface display unit can be employed for any image display application to enhance image quality. For example, a virtual reality headset to remove the screen door effect.