Patents by Inventor Andrew Whiting

Andrew Whiting has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250114509
    Abstract: An arteriovenous graft system including an arteriovenous graft with a valve device. The valve device has an open state in which fluid flow through the graft is possible, and a closed state in which the fluid flow through the arteriovenous graft is blocked. The graft system includes an actuator device to actuate the valve device between the closed state and the open state. A transmission cable connects the actuator device with the valve device. The actuator device includes at least one movable magnet that connects to a rotatable plate which is equipped with a spiralled groove. The spiralled groove receives a pin that is movable in a linear path. The pin is connected to the transmission cable so as to arrange that motion of the magnet translates into a linear displacement of the pin and the transmission cable connected thereto.
    Type: Application
    Filed: December 16, 2024
    Publication date: April 10, 2025
    Inventors: Nicholas Andrew White, Tim Horeman, Joris Ivo Rotmans, Koen Elzert Adriaan van der Bogt
  • Patent number: 12269805
    Abstract: Disclosed herein are small molecule inhibitors of platelet function, and methods of using the small molecules to treat diseases, such as platelet hemostasis and thrombosis. In particular, disclosed herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof: wherein the substituents are as described.
    Type: Grant
    Filed: October 19, 2022
    Date of Patent: April 8, 2025
    Assignees: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Michael Holinstat, Reheman Adili, Andrew White, Theodore R. Holman
  • Publication number: 20250074893
    Abstract: Provided herein are methods of synthesizing quinazoline compounds comprising at least one atropisomeric center.
    Type: Application
    Filed: November 13, 2024
    Publication date: March 6, 2025
    Applicants: Genentech, Inc., Hoffmann-La Roche Inc.
    Inventors: NGIAP-KIE LIM, JEFF SHEN, LAUREN ELIZABETH SIROIS, JACOB C. TIMMERMAN, ETIENNE TRACHSEL, NICHOLAS ANDREW WHITE, JIE XU, HAIMING ZHANG, STEPHAN BACHMANN, RAPHAEL BIGLER, KYLE BRADLEY PASCUAL CLAGG, ANTONIO GIOVANNI DIPASQUALE, FRANCIS GOSSELIN, UGO JONATHAN ORCEL, ROLAND CHRISTOPH MEIER
  • Publication number: 20250059155
    Abstract: Provided herein are methods to synthesize compounds useful in the treatment of cancer where such compounds comprise a quinazolinyl core moiety and at least one stereoisomeric or atropisomeric moiety.
    Type: Application
    Filed: July 18, 2024
    Publication date: February 20, 2025
    Applicants: Genentech, Inc., Hoffmann-La Roche Inc.
    Inventors: Rene LEBL, Ngiap Kie LIM, Roland Christoph MEIER, Ugo Jonathan ORCEL, Joerg SEDELMEIER, Jeff SHEN, Lauren Elizabeth SIROIS, Jacob C. TIMMERMAN, Etienne TRACHSEL, Nicholas Andrew WHITE, Jie XU, Haiming ZHANG, Stephan BACHMANN, Thomas Michael BASS, Raphael BIGLER, Johannes Adrian BURKHARD, Kyle Bradley Pascual CLAGG, Francis GOSSELIN, Chong HAN, Dainis KALDRE, Sean M. KELLY, Sebastian HEROLD, Christian LEITNER
  • Patent number: 12196145
    Abstract: A method of controlling an idle speed of an engine of a vehicle, includes the steps of determining that the engine is decelerating to or is operating at a nominal idle speed, determining that a vehicle brake is applied, determining an actual or projected electrical load of at least part of a vehicle electrical system is beyond an electrical load threshold, and increasing the engine speed to or maintaining the speed of the engine at a speed greater than the nominal idle speed range as a function of the electrical load to increase the electrical output of a generator coupled to the engine. The method may include determining that the brake is ceasing to be applied and then decreasing the engine speed to or toward the nominal idle speed.
    Type: Grant
    Filed: May 31, 2023
    Date of Patent: January 14, 2025
    Assignee: FCA US LLC
    Inventors: Manvinder Singh, Andrew White, Ryan Masters
  • Patent number: 12172982
    Abstract: Provided herein are methods of synthesizing quinazoline compounds comprising at least one atropisomeric center.
    Type: Grant
    Filed: August 10, 2021
    Date of Patent: December 24, 2024
    Assignees: Genentech, Inc., Hoffmann-La Roche Inc.
    Inventors: Ngiap-Kie Lim, Jeff Shen, Lauren Elizabeth Sirois, Jacob C. Timmerman, Etienne Trachsel, Nicholas Andrew White, Jie Xu, Haiming Zhang, Stephan Bachmann, Raphael Bigler, Kyle Bradley Pascual Clagg, Antonio Giovanni Dipasquale, Francis Gosselin, Ugo Jonathan Orcel, Roland Christoph Meier
  • Patent number: 12163054
    Abstract: Aspects described herein generally relate to a sol-gel that is the reaction product of an organosilane, a metal alkoxide, an acid, and a thio-lanthanide salt having a solubility of about 1 gram or greater per gram of sol-gel at 23° C. The thio-lanthanide salt includes a cation and a thio-ligand. The cation can be lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, scandium, yttrium, cobalt, calcium, strontium, barium, and zirconium. In another aspect, a component, such as a vehicle component, includes a metal substrate and a sol-gel disposed on the metal substrate. Methods can include forming a sol-gel by mixing a metal alkoxide and an acid to form a first mixture; mixing with the first mixture an organosilane to form a second mixture; and mixing with the second mixture a lanthanide salt to form a third mixture.
    Type: Grant
    Filed: September 1, 2023
    Date of Patent: December 10, 2024
    Assignee: THE BOEING COMPANY
    Inventors: Waynie M. Schuette, Patrick J. Kinlen, Paul Andrew White
  • Patent number: 12161066
    Abstract: A cleaning mechanism of a combine harvester, for cleaning threshed and separated crop material, including a grain pan for receiving threshed and separated crop material and transporting the crop material rearwardly; a chaffer installed proximate the grain pan for receiving material from the grain pan where the chaffer includes a plurality of longitudinal channels with non-planar surfaces giving each channel a curved or trapezoidal cross section and at least two of the chaffer channels have an asymmetric non-planar surface with a greater part of the surface area facing the side portions of the chaffer; and a fan that causes an air flow through the chaffer to lift up discardable parts from the crop material and transport the discardable parts out of the combine harvester.
    Type: Grant
    Filed: August 26, 2021
    Date of Patent: December 10, 2024
    Assignee: AGCO International GmbH
    Inventors: Alastair Cameron Morrison, Morten Leth Bilde, Andrew White
  • Publication number: 20240401541
    Abstract: A method of controlling an idle speed of an engine of a vehicle, includes the steps of determining that the engine is decelerating to or is operating at a nominal idle speed, determining that a vehicle brake is applied, determining an actual or projected electrical load of at least part of a vehicle electrical system is beyond an electrical load threshold, and increasing the engine speed to or maintaining the speed of the engine at a speed greater than the nominal idle speed range as a function of the electrical load to increase the electrical output of a generator coupled to the engine. The method may include determining that the brake is ceasing to be applied and then decreasing the engine speed to or toward the nominal idle speed.
    Type: Application
    Filed: May 31, 2023
    Publication date: December 5, 2024
    Inventors: Manvinder Singh, Andrew White, Ryan Masters
  • Publication number: 20240370570
    Abstract: Disclosed is a machine learning model architecture that leverages existing large language models to analyze log files for security vulnerabilities. In some configurations, log files are processed by an encoder machine learning model to generate embeddings. Embeddings generated by the encoder model are used to construct graphs. The graphs are in turn used to train a graph classifier model for identifying security vulnerabilities. The encoder model may be an existing general-purpose large language model. In some configurations, the nodes of the graphs are the embedding vectors generated by the encoder model while edges represent similarities between nodes. Graphs constructed in this way may be pruned to highlight more meaningful node topologies. The graphs may then be labeled based on a security analysis of the corresponding log files. A graph classifier model trained on the labeled graphs may be used to identify security vulnerabilities.
    Type: Application
    Filed: May 4, 2023
    Publication date: November 7, 2024
    Inventors: Leo Moreno BETTHAUSER, Andrew White WICKER, Bryan (Ning) XIA
  • Publication number: 20240309224
    Abstract: The present disclosure is directed to processes, compositions and agents for inhibiting corrosion in various substrates, for example metal substrates. The present disclosure is also directed to corrosion inhibitors comprising organometallic polymers such as metal-organic frameworks (MOFs), including compositions and processes comprising MOFs for inhibiting corrosion in metal substrates.
    Type: Application
    Filed: May 8, 2024
    Publication date: September 19, 2024
    Inventors: James Ivan MARDEL, Ivan Stewart COLE, Paul Andrew WHITE, Anthony Ewart HUGHES, Tracey Anne MARKLEY, Timothy Graham HARVEY, Joseph OSBORNE, Erik SAPPER
  • Publication number: 20240287319
    Abstract: The present disclosure relates to agents, compositions, and methods for inhibiting corrosion in various substrates, for example in metal substrates. The present disclosure also relates to compositions for inhibiting corrosion comprising at least one organic heterocyclic compound and at least one metal salt or mixed metal salt selected from rare earth, alkali earth and transition metals.
    Type: Application
    Filed: March 19, 2024
    Publication date: August 29, 2024
    Inventors: James Ivan MARDEL, Ivan Stewart COLE, Paul Andrew WHITE, Anthony Ewart HUGHES, Tracey Anne MARKLEY, Timothy Graham HARVEY, Joseph OSBORNE, Erik Ivan SAPPER
  • Patent number: 12071422
    Abstract: Provided herein are methods to synthesize compounds useful in the treatment of cancer where such compounds comprise a quinazolinyl core moiety and at least one stereoisomeric or atropisomeric moiety.
    Type: Grant
    Filed: February 3, 2023
    Date of Patent: August 27, 2024
    Assignees: Genentech, Inc., Hoffmann-La Roche Inc.
    Inventors: Rene Lebl, Ngiap Kie Lim, Roland Christoph Meier, Ugo Jonathan Orcel, Joerg Sedelmeier, Jeff Shen, Lauren Elizabeth Sirois, Jacob C. Timmerman, Etienne Trachsel, Nicholas Andrew White, Jie Xu, Haiming Zhang, Stephan Bachmann, Thomas Michael Bass, Raphael Bigler, Johannes Adrian Burkhard, Kyle Bradley Pascual Clagg, Francis Gosselin, Chong Han, Dainis Kaldre, Sean M. Kelly, Sebastian Herold, Christian Leitner
  • Patent number: 12018177
    Abstract: The present disclosure is directed to processes, compositions and agents for inhibiting corrosion in various substrates, for example metal substrates. The present disclosure is also directed to corrosion inhibitors comprising organometallic polymers such as metal-organic frameworks (MOFs), including compositions and processes comprising MOFs for inhibiting corrosion in metal substrates.
    Type: Grant
    Filed: February 28, 2022
    Date of Patent: June 25, 2024
    Assignee: THE BOEING COMPANY
    Inventors: James Ivan Mardel, Ivan Stewart Cole, Paul Andrew White, Anthony Ewart Hughes, Tracey Anne Markley, Timothy Graham Harvey, Joseph Osborne, Erik Sapper
  • Patent number: 11987726
    Abstract: The present disclosure relates to agents, compositions, and methods for inhibiting corrosion in various substrates, for example in metal substrates. The present disclosure also relates to compositions for inhibiting corrosion comprising at least one organic heterocyclic compound and at least one metal salt or mixed metal salt selected from rare earth, alkali earth and transition metals.
    Type: Grant
    Filed: January 23, 2023
    Date of Patent: May 21, 2024
    Assignee: THE BOEING COMPANY
    Inventors: James Ivan Mardel, Ivan Stewart Cole, Paul Andrew White, Anthony Ewart Hughes, Tracey Anne Markley, Timothy Graham Harvey, Joseph Osborne, Erik Sapper
  • Publication number: 20240013216
    Abstract: A method performed by a session initiation system (SIS) for reducing a time to authenticate a user includes communicating, to a mobile device, session identifying information associated with a session. The mobile device is configured to subsequently communicate at least part of the session identifying information to an authentication server, and the authentication server is configured to subsequently communicate account information associated with the session identifying information to an intermediate gateway.
    Type: Application
    Filed: December 4, 2020
    Publication date: January 11, 2024
    Inventor: Brett Andrew White
  • Patent number: 11857102
    Abstract: A drip filter coffee making device has a filter basket with a lid. The lid supports a water dispenser for wetting grounds in the filter basket. The basket is removable from a body of the device. The lid may have a dampened opening motion, biased into an open position by a spring.
    Type: Grant
    Filed: September 3, 2020
    Date of Patent: January 2, 2024
    Assignee: BREVILLE PTY LIMITED
    Inventors: Con Psarologos, Gerard Andrew White, Alex Ming Duk Leung, Richard Harrod
  • Publication number: 20230416539
    Abstract: Aspects described herein generally relate to a sol-gel that is the reaction product of an organosilane, a metal alkoxide, an acid, and a thio-lanthanide salt having a solubility of about 1 gram or greater per gram of sol-gel at 23° C. The thio-lanthanide salt includes a cation and a thio-ligand. The cation can be lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, scandium, yttrium, cobalt, calcium, strontium, barium, and zirconium. In another aspect, a component, such as a vehicle component, includes a metal substrate and a sol-gel disposed on the metal substrate. Methods can include forming a sol-gel by mixing a metal alkoxide and an acid to form a first mixture; mixing with the first mixture an organosilane to form a second mixture; and mixing with the second mixture a lanthanide salt to form a third mixture.
    Type: Application
    Filed: September 1, 2023
    Publication date: December 28, 2023
    Inventors: Waynie M. SCHUETTE, Patrick J. KINLEN, Paul Andrew WHITE
  • Patent number: 11833203
    Abstract: There are described novel compounds of formula I: (I) in which, in which A1, A2, A3, A4, R1 and R2 are each as herein defined, for use in the treatment or alleviation of an RAR mediated condition; and methods related thereto.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: December 5, 2023
    Inventors: Andrew Whiting, Carrie Ambler, Mark Coles, David Chisholm
  • Patent number: D1072550
    Type: Grant
    Filed: October 6, 2023
    Date of Patent: April 29, 2025
    Assignee: Breville Pty Limited
    Inventors: Jonathan Mark Woodcock, Gerard Andrew White, Han Young Hwang, David Davenport