Abstract: Stair system for outdoor building structures, such as decks are described. The stair system can include one or more perimeter frame members, one or more stair tread brackets; one or more stair tread members, and one or more fastening brackets coupled to the perimeter frame members, when in an assembled configuration.

Abstract: Described in exemplary embodiments herein are methods, compositions, and kits for diagnosing, prognosing, monitoring, treating and/or preventing a hemopoietic malignancy and/or relapse thereof in a subject. In some embodiments, the methods can include determining an average cellular mass of cells in a sample from the subject and/or detecting one or more molecular signatures in one or more of the cells. In some embodiments, treatment includes administering one or more BCR-ABL tyrosine kinase inhibitors or a pharmaceutical formulation thereof, one or more pre-BCR signaling pathway inhibitors or a pharmaceutical formulation thereof, one or more p38 MAPK inhibitors or a pharmaceutical formulation thereof; or any combination thereof.

Abstract: A cooling device comprises a thermally conductive material preferably having a large surface area, such as a plurality of fins. The cooling device clamps or slides onto an energy-introducing cannula and can exchange heat with the surrounding air, or with a coolant enclosed in a camber or shroud around the cooling device. The coolant can be circulated via a pump connected to the shroud. The device and/or shroud can be stabilized and positioned by a positioning cone or spacer. The cooling device and method reduces, minimizes or eliminates thermal effects at critical points along the cannula, while enabling the distal end of the cannula, at which treatment is occurring, to reach a temperature sufficient to kill tumor cells.