Abstract: Syringe plunger rods comprising an elongate body formed from a composition comprising one or more of virgin material, a sterilization-stable recycled resin and a biobased compositions are described. Plunger rods comprising a plurality of ribs, some of which may have a plurality of openings, are also described. The plunger rods requiring less material while maintaining sufficient structural integrity to function properly.

Abstract: An infusion adapter for connection with an infusion fluid container includes a connection portion configured to engage an injection port of an infusion fluid container, and a port configured to connect to an intravenous line, with the port in fluid communication with the connection portion. The connection portion includes a retaining ring extending radially outward from the connection portion, with the retaining ring configured to securely connect the infusion adapter to the infusion fluid container to substantially prevent disconnection of the infusion adapter from the infusion fluid container once the infusion adapter is connected to the infusion fluid container. The retaining ring includes an indicator configured to provide visualization of insertion of the connection portion into an injection port of an infusion fluid container.

Abstract: A method for correcting nucleotide incorporation signals for fluid potential effects or disturbances arising in nucleic acid sequencing-by-synthesis includes: disposing a plurality of template polynucleotide strands in a plurality of defined spaces disposed on a sensor array, the template polynucleotide strands having a sequencing primer and a polymerase bound therewith; exposing the template polynucleotide strands to a series of flows of nucleotide species flowed through a fluid manifold, the fluid manifold comprising passages for flowing nucleotide species and a branch passage for flowing a solution, the branch passage comprising a reference electrode and a sensing electrode; obtaining a plurality of nucleotide incorporation signals corresponding to the plurality of defined spaces, the nucleotide incorporation signals having a signal intensity related to a number of nucleotide incorporations; and correcting at least some of the plurality of nucleotide incorporation signals for fluid potential effects or dis

Abstract: An implantable blood pump system is disclosed herein. The implantable blood pump system includes an implantable blood pump, a controller coupled to the blood pump, a connector receptacle, and a connector insert. The connector receptacle can include a plurality of contacts, and a following surface. The connector insert can be received within the connector receptacle to couple a plurality of insert contacts with the plurality of contacts of the connector receptacle. The connector insert can include walls defining a follower receptacle that can receive a portion of the following surface when the connector insert is in a desired alignment with respect to the connector receptacle, and a cam surface that can engage with the following surface to bias the connector insert to the desired alignment with respect to the connector receptacle when the connector insert is inserted into the connector receptacle.

Abstract: An implantable blood pump system is disclosed herein. The implantable blood pump system includes an implantable blood pump, a controller coupled to the blood pump, a connector receptacle, and a connector insert. The connector receptacle can include a plurality of contacts, and a following surface. The connector insert can be received within the connector receptacle to couple a plurality of insert contacts with the plurality of contacts of the connector receptacle. The connector insert can include walls defining a follower receptacle that can receive a portion of the following surface when the connector insert is in a desired alignment with respect to the connector receptacle, and a cam surface that can engage with the following surface to bias the connector insert to the desired alignment with respect to the connector receptacle when the connector insert is inserted into the connector receptacle.

Abstract: A sequencing system includes an automated sequencing instrument adapted to determine variant calls for one or more extracted polynucleotide samples with a performance of at least 98.5% raw read accuracy and a run time in a range of 5 hours to 14 hours to determine variant calls for 4 extracted polynucleotide samples using a targeted assay with one DNA pool per sample and an average amplicon size in a range of 100 to 120 bases.

Abstract: A passive safety needle device is disclosed having a housing, a needle hub, a needle cannula, a retractable sheath, a spring to bias the retractable sheath in a distal direction to cover the distal end of the needle cannula, a radial protrusion to cause the spring to move from the proximal spring position to the distal spring position, and a catch to secure the distal end of the spring to the distal end of the housing. The spring may bias the retractable sheath in a distal direction to cover the distal end of the needle cannula. The radial protrusion causes the spring to move from a proximal spring position to the distal spring position towards the catch located at the distal end of the housing.

Abstract: A stopper includes a main body portion defining an open rearward end configured to receive the plunger rod, an engagement portion provided along an inner circumference of the main body portion configured to engage at least a top portion of the plunger rod, a closed front end forming a flexible roof, and a first perimetrical skirt extending around an outer circumference of the main body portion toward the closed front end of the main body portion. When fluid pressure is increased inside the syringe barrel during an injection, the flexible roof expands in a radial direction toward an inner wall of the syringe barrel, the first perimetrical skirt is forced against the inner wall of the syringe barrel, and an engagement between the plunger rod and the engagement portion forces the main body portion to expand in the radial direction toward the inner wall of the syringe barrel.

Abstract: A medical connector includes a body having a distal end, a proximal end, and a sidewall extending between the distal end and the proximal end, a helical thread extending radially outward from a surface of the sidewall and comprising a crest portion, flank portions, and a root portion with the flank portions connecting the crest portion to the root portion, and at least one deformable protrusion extending radially outward from the root portion of the helical thread.

Abstract: The disclosure generally relates to systems, methods, and apparatuses for magnetic bead loading. An example embodiment of the disclosure relates to mixing magnetic beads with sequencing beads to form a solution. The solution containing both beads is injected onto a microchip having a plurality of microwells. The magnetic beads may have larger diameter than the microwell while the sequencing beads may have a smaller diameter, allowing them to enter and reside in the microwell. One or more magnets positioned under the microchip move back and forth across the microchip surface. The magnetic beads form a line and follow the movement of the magnets. During rounds of sweeping, the sequencing beads load into the respective wells. The magnets may be disengaged and the magnetic beads may be washed away after the sequencing beads are loaded.

Abstract: A method for correcting nucleotide incorporation signals for fluid potential effects or disturbances arising in nucleic acid sequencing-by-synthesis includes: disposing a plurality of template polynucleotide strands in a plurality of defined spaces disposed on a sensor array, the template polynucleotide strands having a sequencing primer and a polymerase bound therewith; exposing the template polynucleotide strands to a series of flows of nucleotide species flowed through a fluid manifold, the fluid manifold comprising passages for flowing nucleotide species and a branch passage for flowing a solution, the branch passage comprising a reference electrode and a sensing electrode; obtaining a plurality of nucleotide incorporation signals corresponding to the plurality of defined spaces, the nucleotide incorporation signals having a signal intensity related to a number of nucleotide incorporations; and correcting at least some of the plurality of nucleotide incorporation signals for fluid potential effects or dis

Abstract: A stopper includes a main body portion defining an open rearward end configured to receive the plunger rod, an engagement portion provided along an inner circumference of the main body portion configured to engage at least a top portion of the plunger rod, a closed front end forming a flexible roof, and a first perimetrical skirt extending around an outer circumference of the main body portion toward the closed front end of the main body portion. When fluid pressure is increased inside the syringe barrel during an injection, the flexible roof expands in a radial direction toward an inner wall of the syringe barrel, the first perimetrical skirt is forced against the inner wall of the syringe barrel, and an engagement between the plunger rod and the engagement portion forces the main body portion to expand in the radial direction toward the inner wall of the syringe barrel.

Abstract: A medical connector includes a body having a distal end, a proximal end, and a sidewall extending between the distal end and the proximal end, a helical thread extending radially outward from a surface of the sidewall and comprising a crest portion, flank portions, and a root portion with the flank portions connecting the crest portion to the root portion, and at least one deformable protrusion extending radially outward from the root portion of the helical thread.

Abstract: A food grinder comprises a base housing a motor, a throat portion coupled to the base, a receiving tube coupled to the throat, a feeding tray coupled to an upper end of the receiving tube, a selectively rotatable auger selectively insertable into and removable from the throat portion, and a storage tray sized and shaped to be selectively insertable into and removable from the feeding tray. The storage tray comprises a main body having a plurality of depressions formed in a top surface thereof. Each depression is sized and shaped to hold one or more accessories for use with the food grinder.

Abstract: An implantable blood pump system is disclosed herein. The implantable blood pump system includes an implantable blood pump, a controller coupled to the blood pump, a connector receptacle, and a connector insert. The connector receptacle can include a plurality of contacts, and a following surface. The connector insert can be received within the connector receptacle to couple a plurality of insert contacts with the plurality of contacts of the connector receptacle. The connector insert can include walls defining a follower receptacle that can receive a portion of the following surface when the connector insert is in a desired alignment with respect to the connector receptacle, and a cam surface that can engage with the following surface to bias the connector insert to the desired alignment with respect to the connector receptacle when the connector insert is inserted into the connector receptacle.

Abstract: A method of removing an auger from a food grinder via a food stomper. The food stomper has structure to engage the auger to transmit force on the stomper to the auger. As such, the stomper serves dual purpose of filling the grinder with food and as a tool for cleaning or otherwise removing an auger from the appliance.

Abstract: A method for correcting nucleotide incorporation signals for fluid potential effects or disturbances arising in nucleic acid sequencing-by-synthesis includes: disposing a plurality of template polynucleotide strands in a plurality of defined spaces disposed on a sensor array, the template polynucleotide strands having a sequencing primer and a polymerase bound therewith; exposing the template polynucleotide strands to a series of flows of nucleotide species flowed through a fluid manifold, the fluid manifold comprising passages for flowing nucleotide species and a branch passage for flowing a solution, the branch passage comprising a reference electrode and a sensing electrode; obtaining a plurality of nucleotide incorporation signals corresponding to the plurality of defined spaces, the nucleotide incorporation signals having a signal intensity related to a number of nucleotide incorporations; and correcting at least some of the plurality of nucleotide incorporation signals for fluid potential effects or dis

Abstract: A safety needle device having a housing, a retractable sheath, and a needle cannula. The retractable sheath includes a tubular portion that is slideably mounted about a portion of the housing to completely or partially encase the length of the cannula. The retractable sheath includes a sheath bevel at the distal end having a blunted or angled tip. The angled tip being configured to suitable injection angles and may be fixed or rotatable. The sheath bevel may include a skin-engaging contact surface at the distal end. The needle may be connected to a needle hub at the proximal end of the housing and includes a needle bevel at the distal end. The sheath bevel and needle bevel may be offset from each other. A safety needle device having a retractable sheath having a graduated injection depth gauge to indicate needle penetration is also disclosed.

Abstract: A stomper for a food grinder comprises a distal end adapted to push food into a receiving tube of a food grinder, a proximal handle end adapted for a user to grasp the stomper while pushing food into the receiving tube of the food grinder, an elongated shaft between the distal end and the proximal handle end, a channel defined in the proximal handle end, and a bayonet projecting from one or more internal walls of the channel. The bayonet is adapted to engage a protrusion on an auger of the food grinder to apply a pulling force to remove the auger from the food grinder.

Abstract: A chemical sensor for analyte solutions utilizes AC excitation of a sample distributed in one or more micro-wells of a measurement device. The sensors utilize narrowband filtering of the measured signal(s), resulting in a large reduction in noise. Synchronous detection is utilized to provide high discrimination of the desired signal from noise or interfering sources. Conductance and by extension impedance is measured by applying a constant alternating current (AC) voltage across the electrodes of each micro-well and measuring the resulting current.