Abstract: Provided herein are pharmaceutical formulations of the KDM4 inhibitor 3-({[(4r)-7-{methyl[4-(propan-2-yl)phenyl]amino}-3,4-dihydro-2h-1-benzopyran-4-yl]methyl}amino)pyridine-4-carboxylic acid.

Abstract: Microelectronic assemblies, and related devices and methods, are disclosed herein. For example, in some embodiments, a microelectronic assembly may include a package substrate having a core substrate with a first conductive structure having a first thickness on the core substrate, and a second conductive structure having a second thickness on the core substrate, where the first thickness is different than the second thickness.

Abstract: A filtering device for an evacuation station includes a filter bag configured to collect debris evacuated from a cleaning robot by an evacuation station. The filtering device includes an interface assembly configured to interface with the evacuation station. The interface assembly includes (i) a base attached to the filter bag along an opening of the filter bag, (ii) an access door configured to provide or limit access to a space within the filter bag depending on whether the access door is in an open position or a closed position, and (iii) one or more hinges connecting the base to the access door. The access door is rotatable around the one or more hinges from the closed position to the open position.

Abstract: The present application provides tobacco inbred plants dS1746, dS1746MS, dS1564 and dS1564MS. The present application also provides parts of such plants and products made from those parts. The present application also includes progeny of the provided plants including hybrids.

Abstract: The invention provides competitive inhibitors of farnesyl transferase, compositions comprising the competitive inhibitors of farnesyl transferase, and their use as antifungal agents and as agents for the prevention of the formation or growth of biofilms.

Abstract: In various examples, disclosed techniques use a banding detector neural network to identify the locations and sizes of banding artifacts in pixel regions of an input image. The neural network generates a band size map that identifies at least one banding artifact in the input image. The band size map can include a set of predicted band size values, each of which corresponds to a respective pixel of the input image and represents a distance between edges of a banding artifact. The band size map and the input image are provided as input to a stochastic bilateral blur filter, which generates a de-banded image by applying blurring effects to the input image at the band locations indicated by the band size map. An inverse tone mapping operation is then performed to convert the de-banded image to an image that does not have banding artifacts.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for processing data about a medical encounter using neural networks. One of the methods includes obtaining features for a medical encounter associated with the patient, each feature representing a corresponding health event associated with the medical encounter and each of the plurality of features belonging to a vocabulary of possible features that each represent a different health event; and generating respective final embeddings for each of the features for the medical encounter by applying a sequence of one or more self-attention blocks to the features for the medical encounter, wherein each of the one or more self-attention blocks receives a respective block input for each of the features and applies self-attention over the block inputs to generate a respective block output for each of the features.

Abstract: This invention relates to a lubricating oil composition comprising or resulting from the admixing of: (i) at least 50 mass %, based upon the weight of the lubricating oil composition, of base oil, (ii) at least one capped dispersant having number average molecular weight (Mn) of less than 1600 g/mol, (iii) at least one magnesium containing detergent, (iv) at least one calcium containing detergent, (v) at least one copolymer viscosity modifier that has: 1) a ratio of relative KV140/relative KV20 of 1.9 or more; 2) a ratio of relative KV100/relative KV70 or 1.30 or more; and 3) a viscosity index (ASTM 2270D) of 320 or more, when 1), 2) and 3) are measured on blend, having a KV100 of about 8 cSt, of the copolymer viscosity modifier and a group III base oil having a KV100 (ASTM D445) of about 4 cSt and a viscosity index (ASTM D2270) of about 120.

Abstract: Described herein are novel trinucleotide cap analogs and methods of making and using the same. Also described herein is an RNA molecule comprising a 5?-cap, wherein the 5?-cap includes a trinucleotide cap analog as described herein. Methods of inducing a therapeutic effect in a 5 subject are also described herein, the methods including a step of administering to the subject an RNA molecule including the trinucleotide cap analog.

Abstract: The invention relates to a multi-component composition for the manufacture of polyurethane/urea cementitious hybrid system, comprising at least one isocyanate component selected from the group consisting of monoisocyanate, polyisocyanate and NCO terminated prepolymer, at least one polyol, water, catalyst, at least one acidic additive, and hydraulic binder, wherein the acidic additive is at least one selected from the group consisting of Lewis acids, acid precursors and acidic buffers and is in an amount of 0.01 to 3 wt %, based on the total weight of the composition, to the preparation thereof, and to the use of the composition for the preparation of a flooring, waterproofing, screed, grouting, primer, wall paint, roofing or coating in construction applications.

Abstract: Disclosed are compounds of Formula 1, including all geometric and stereoisomers, wherein R1, R2, R3, A and T are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the disclosure.

Abstract: The present disclosure relates to a music generation method, apparatus and system, and storage medium. In an embodiment of the present disclosure: obtaining text information, and converting the text information into a corresponding voice audio; obtaining an initial music audio, wherein the initial music audio comprises a music key point, and music characteristics of the initial music audio have a sudden change at the position of an audio key point; and on the basis of the position of the music key point, synthesizing the voice audio and the initial music audio to obtain a target music audio. In the target music audio, the voice audio appears at the position of the music key point of the initial music audio. Thus, a music audio is generated from text information, and the user can customize the content of the text information and customize the initial music audio.

Abstract: The present disclosure provides tobacco having genetic modification(s) in a group of ERF genes. Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Further provided are compositions and methods for producing tobacco plants having novel mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or alkaloids while maintaining tobacco leaf grade and tobacco product quality.

Abstract: Implementations described herein relate to methods, systems, and computer-readable media to localize dynamic content. In some implementations, a computer-implemented method includes receiving visual content associated with a game from a first client locale, the visual content including text being represented at the first client locale by a first language, converting the text to generate translated text in at least a second language associated with a second client locale, and storing the translated text in a database in association with the visual content.

Abstract: A biometric input system for an electronic device is provided. The biometric input system may be a fingerprint sensing system. The biometric input system includes a biometric sensing component, which may be a capacitive sensing component. The biometric input system also includes a composite cover element, which may be a dielectric cap or coating, and the biometric sensing component is capable of receiving a biometric input from a user through the composite cover element. Electronic devices including the biometric input system are also provided.

Abstract: Apparatuses, systems, and techniques to perform active learning.

Abstract: Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25HC3S) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide, e.g., a cyclodextrin (CD), are provided. The compositions may be used to prevent and/or treat a variety of diseases and conditions, including organ failure (e.g. acute liver failure), high cholesterol/high lipids, and various inflammatory diseases and conditions.

Abstract: Systems and methods are described herein to control brightness based on image content or other inputs to a display system. A dual-control system may integrate both slow control operations and fast control operations into a cohesive brightness management system. By using both shorter-term (e.g., fast control) and longer-term (e.g., slow control) brightness adjustment operations, the electronic device may quickly respond to high luminance and high brightness situations that may cause burn-in into the display, image artifacts, or other damage. Responding quickly to these high consumption situations may prevent damage or perceivable upset to an ongoing process, among other benefits.

Abstract: Systems and methods are disclosed herein for generating and modifying a workflow comprising a series of webpages based on an online document. A document management system accesses an online document selected by a user and classifies each field of the online document into one of a set of categories. For each category, the system generates a form webpage comprising questions corresponding to each field classified as the category and combines the generated webpages to create a workflow. The system may modify the workflow by generating and adding one or more additional form webpages based on one or more answers provided by an entity completing the webform page. In response to the entity completing the modified generated workflow, the system generates a completed document based on the online document and the answers provided by the entity.

Abstract: A deep state space generative model is augmented with intervention prediction. The state space model provides a principled way to capture the interactions among observations, interventions, critical event occurrences, true states, and associated uncertainty. The state space model can include a discrete-time hazard rate model that provides flexible fitting of general survival time distributions. The state space model can output a joint prediction of event risk, observation and intervention trajectories based on patterns in temporal progressions, and correlations between past measurements and interventions.