Patents by Inventor Andrew Y. Thurkauf

Andrew Y. Thurkauf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5428164
    Abstract: This invention encompasses compounds of the formulas: ##STR1## where R.sub.1, R.sub.3, R.sub.4, R.sub.6, X, Y, and Z are T are variables; andM is ##STR2## where R.sub.2 is a variable; or R.sub.1 and R.sub.2 together may represent --(CH.sub.2).sub.n.sbsb.1 where n.sub.1 is 1, 2, or 3.These compounds are highly selective partial agonists or antagonists at brain dopamine receptor subtypes or prodrugs thereof and are useful in the diagnosis and treatment of affective disorders such as schizophrenia and depression as well as certain movement disorders such as Parkinsonism. Furthermore compounds of this invention may be useful in treating the extraparamidyl side effects associated with the use of conventional neuroleptic agents.
    Type: Grant
    Filed: November 8, 1993
    Date of Patent: June 27, 1995
    Assignee: Neurogen Corporation
    Inventors: Andrew Y. Thurkauf, Alan J. Hutchison