Patents by Inventor Andrew Zhuang Wang

Andrew Zhuang Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOMATRIX SCAFFOLDS
    Publication number: 20200002667
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Application
    Filed: February 12, 2019
    Publication date: January 2, 2020
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Yunfang Wang, Lola Cynthia McAdams Reid, Mitsuo Yamauchi, Cai-Bin Cui, Andrew Zhuang Wang, Michael Edward Werner
  • BIOMATRIX SCAFFOLDS FOR USE IN DIAGNOSING AND MODELING CANCER
    Publication number: 20190234937
    Abstract: Described herein are in vitro cancer metastasis models that recapitulate biological facets of organ specificity as indicated by the behavior of human colorectal cancer cells when on substrata of liver and lung biomatrix scaffolds, organ-specific matrix extracts generated by novel decellularization strategies. Tumor cells spontaneously formed colonies that mimicked in vivo metastatic lesions in terms of histology, biology and genetic and other phenotypic traits. Not to be bound by theory, it is postulated that responses of tumors to radiation or chemotherapeutic agents proved dependent on the matrix substratum used; thus, thus the scaffolds are believed to provide a powerful tool for cancer research and diagnosis.
    Type: Application
    Filed: July 11, 2017
    Publication date: August 1, 2019
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Andrew Zhuang Wang, Xi Tian, Lola M. Reid
  • Biomatrix scaffolds
    Patent number: 10246678
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Grant
    Filed: July 27, 2016
    Date of Patent: April 2, 2019
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Yunfang Wang, Lola Cynthia McAdams Reid, Mitsuo Yamauchi, Cai-Bin Cui, Andrew Zhuang Wang, Michael Edward Werner
  • BIOMATRIX SCAFFOLDS
    Publication number: 20170015974
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Application
    Filed: July 27, 2016
    Publication date: January 19, 2017
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Yunfang WANG, Lola Cynthia McAdams REID, Mitsuo YAMAUCHI, Cai-Bin CUI, Andrew Zhuang WANG, Michael Edward WERNER
  • BIOMATRIX SCAFFOLDS
    Publication number: 20150110753
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Application
    Filed: August 8, 2014
    Publication date: April 23, 2015
    Applicant: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
    Inventors: Yunfang WANG, Lola Cynthia McAdams REID, Mitsuo YAMAUCHI, Cai-Bin CUI, Andrew Zhuang WANG, Michael Edward WERNER
  • Biomatrix scaffolds
    Patent number: 8802081
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Grant
    Filed: July 1, 2011
    Date of Patent: August 12, 2014
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Yunfang Wang, Lola Cynthia McAdams Reid, Mitsuo Yamauchi, Cai-Bin Cui, Andrew Zhuang Wang, Michael Edward Werner
  • Biomatrix Scaffolds
    Publication number: 20130195811
    Abstract: The present invention provides biomatrix scaffolds, a tissue extract enriched for extracellular matrix components and bound growth factors, cytokines and hormones, and methods of making and using same.
    Type: Application
    Filed: July 1, 2011
    Publication date: August 1, 2013
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Yunfang Wang, Lola Cynthia McAdams Ried, Mitsuo Yamauchi, Cai-Bin Cui, Andrew Zhuang Wang, Michael Edward Werner