Abstract: A heart valve prosthesis having an annular support and an occluder-disc pivotally mounted in a fluid passageway of the annular support, where the annular support includes at least a first axis of symmetry. A pier that projects radially inwardly from an inner surface of the annular support and along the first axis of symmetry. A first arm projects inwardly from the inner surface of the annular support and a second arm that projects inwardly from the inner surface of the annular support so as to be in confronting spaced relation to the first arm thereby defining a second axis of symmetry. The first axis of symmetry and the second axis of symmetry are arcuately off-set from one another. A method of operation of the heart valve that reduces wear in the occluder-disc and noise is also presented.