Abstract: Systems and methods for establishing a control channel between a virtualization server and a client device are provided. A virtual desktop session is established between the virtualization server and the client, and the virtualization server executes a virtual desktop instance. The client device executes a first application that is configured to receive a control channel connection request from a second application running within the virtual desktop instance. The second application runs an algorithm to discover an Internet Protocol (IP) address of the client device being used to access the second application. Using the IP address, a control channel outside of the virtual desktop session is established between the first and second applications. Instructions are transmitted from the second application to the first application via the control channel, and the first application is controlled remotely by the second application based on the instructions.

Abstract: The invention relates to the treatment or prevention of an inflammatory skin disease, disorder or condition, by modulating a protein that is normally regulated by caspase-8 in the skin or by increasing caspase-8 activity or level in the skin. Another aspect of the invention relates to methods for diagnosing an inflammatory skin disease, disorder or condition or a predisposition to develop said disease disorder or condition in an individual. Further aspects of the invention relate to methods for identifying target proteins involved in the course or pathology of an inflammatory skin disease, disorder or condition and to methods of screening a candidate compound for treating said disease, disorder or condition. In particular, the invention relates to inflammatory skin diseases such as atopic dermatitis and psoriasis.

Abstract: Systems and methods for partially releasing an appliance from a private branch exchange are shown and described. The method can include issuing a path replacement command to the private branch exchange, receiving a facility message from the private branch exchange destined for one end-point of a communications session, and transmitting the received facility message to another end-point of the communications session.

Abstract: Systems and methods for establishing a communications session among end-points are shown and described. The method can include receiving, from a client computing device at a gateway computing device, a request to establish a communication session with an end-point, the client computing device executing a program that locates address information for the end-point within application output displayed at the client computing device and forwarding at least a portion of the received request to a private branch exchange in communication the gateway computing device, the at least a portion of the received request including the address information of the end-point and address information associated with an end-user of the client computing device.

Abstract: A conference call system comprising at least a gateway, a conference reservation agent and a multiport conference unit, can establish conference calls by calling conference call participants at a phone number specified by the conference call participants. When a user initiates a conference, an identifier is assigned to the conference and a URL referencing this identifier is transmitted to each conference participant. Upon clicking the URL, conference participants are presented with a web-form within which the participants can entered a preferred phone number and further join the conference. The multiport conference unit receives each participant phone number and calls the participants at that phone number. Upon establishing a telecommunication connection with each participant, the multiport conference unit bridges the multiple call legs to establish the conference call.

Abstract: The present invention relates to a splice variant of SIVA, SIVA3, and to its use.

Abstract: The invention relates to caspases and to extracellular use of caspases for regulating cell functions.

Abstract: The present invention relates to the ubiquitination and/or degradation-related activity of a SIVA polypeptide and to agents capable of modulating said activity.

Abstract: A DNA sequence encoding a protein capable of binding to a tumor necrosis factor receptor-associated factor (TRAF) molecule, TRAF-binding proteins, their isoforms, analogs, fragments and derivatives encoded by the DNA sequence, their methods for the production of the DNA sequences and proteins, and the uses for the DNA sequence and proteins.

Abstract: The invention relates to the treatment or prevention of an inflammatory skin disease, disorder or condition, by modulating a protein that is normally regulated by caspase-8 in the skin or by increasing caspase-8 activity or level in the skin. Another aspect of the invention relates to methods for diagnosing an inflammatory skin disease, disorder or condition or a predisposition to develop said disease disorder or condition in an individual. Further aspects of the invention relate to methods for identifying target proteins involved in the course or pathology of an inflammatory skin disease, disorder or condition and to methods of screening a candidate compound for treating said disease, disorder or condition. In particular, the invention relates to inflammatory skin diseases such as atopic dermatitis and psoriasis.

Abstract: The present invention relates to modulation of SIVA2 stability by N-acetylglucosamine, phosphorylation of ubiquitination in treatment or prevention of diseases, disorders or conditions.

Abstract: The present invention relates to a splice variant of SIVA, SIVA3, and to its use.

Abstract: The present invention relates to the ubiquitination and/or degradation-related activity of a SIVA polypeptide and to agents capable of modulating said activity.

Abstract: The present invention relates to a protein, designated NAP (Nemo Associated Protein), that was discovered to inhibit the activation of transcription factor NF-kB by various signals that are important in inflammatory and immune processes. The DNA and the recombinant production of this protein is also disclosed as well as methods of using the protein or encoding DNA.

Abstract: A conference call system comprising at least a gateway, a conference reservation agent and a multiport conference unit, can establish conference calls by calling conference call participants at a phone number specified by the conference call participants. When a user initiates a conference, an identifier is assigned to the conference and a URL referencing this identifier is transmitted to each conference participant. Upon clicking the URL, conference participants are presented with a web-form within which the participants can entered a preferred phone number and further join the conference. The multiport conference unit receives each participant phone number and calls the participants at that phone number. Upon establishing a telecommunication connection with each participant, the multiport conference unit bridges the multiple call legs to establish the conference call.

Abstract: A DNA sequence encoding a protein capable of binding to a tumor necrosis factor receptor-associated factor (TRAF) molecule, TRAF-binding proteins, their isoforms, analogs, fragments and derivatives encoded by the DNA sequence, their methods for the production of the DNA sequences and proteins, and the uses for the DNA sequence and proteins.

Abstract: The invention relates to caspases and to extracellular use of caspases for regulating cell functions.

Abstract: Systems and methods for partially releasing an appliance from a private branch exchange are shown and described. The method can include issuing a path replacement command to the private branch exchange, receiving a facility message from the private branch exchange destined for one end-point of a communications session, and transmitting the received facility message to another end-point of the communications session.

Abstract: Systems and methods for establishing a communications session among end-points are shown and described. The method can include receiving, from a client computing device at a gateway computing device, a request to establish a communication session with an end-point, the client computing device executing a program that locates address information for the end-point within application output displayed at the client computing device and forwarding at least a portion of the received request to a private branch exchange in communication the gateway computing device, the at least a portion of the received request including the address information of the end-point and address information associated with an end-user of the client computing device.

Abstract: A DNA sequence encoding a protein capable of binding to a tumor necrosis factor receptor-associated factor (TRAF) molecule, TRAF-binding proteins, their isoforms, analogs, fragments and derivatives encoded by the DNA sequence, their methods for the production of the DNA sequences and proteins, and the uses for the DNA sequence and proteins.