Patents by Inventor Andrey Sarafanov

Andrey Sarafanov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FACTOR VIII COMPOSITIONS AND METHODS
    Publication number: 20070232788
    Abstract: The present invention provides methods of increasing the half-life and/or specific activity of factor VIII. More specifically, the invention provides methods of increasing the half-life and/or specific activity of factor VIII by substituting one or more amino acids in the A2 domain. It further provides methods for producing such factor VIII mutants. The invention also provides polynucleotides encoding the mutant factor VIII, and methods of treating hemophilia using the polypeptides and polynucleotides of the invention.
    Type: Application
    Filed: March 19, 2007
    Publication date: October 4, 2007
    Applicant: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Evgueni Saenko, Andrey Sarafanov, Natalya Ananyeva
  • FACTOR VIII COMPOSITIONS AND METHODS
    Publication number: 20070232789
    Abstract: The present invention provides methods of increasing the half-life and/or specific activity of factor VIII. More specifically, the invention provides methods of increasing the half-life and/or specific activity of factor VIII by substituting one or more amino acids in the A2 domain. It further provides methods for producing such factor VIII mutants. The invention also provides polynucleotides encoding the mutant factor VIII, and methods of treating hemophilia using the polypeptides and polynucleotides of the invention.
    Type: Application
    Filed: March 19, 2007
    Publication date: October 4, 2007
    Applicant: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Evgueni Saenko, Andrey Sarafanov, Natalya Ananyeva
  • Factor VIII compositions and methods
    Publication number: 20050100990
    Abstract: The present invention provides methods of increasing the half-life and/or specific activity of factor VIII. More specifically, the invention provides methods of increasing the half-life and/or specific activity of factor VIII by substituting one or more amino acids in the A2 domain. It further provides methods for producing such factor VIII mutants. The invention also provides polynucleotides encoding the mutant factor VIII, and methods of treating hemophilia using the polypeptides and polynucleotides of the invention.
    Type: Application
    Filed: October 20, 2004
    Publication date: May 12, 2005
    Applicant: American National Red Cross
    Inventors: Evgueni Saenko, Andrey Sarafanov, Natalya Ananyeva