Patents by Inventor Andrezej Ptasznik

Andrezej Ptasznik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphatidylinositol 3-kinase inhibitors as stimulators of endocrine differentiation
    Patent number: 6413773
    Abstract: This invention pertains to the discovery that inhibition of phosphatidylinositol 3-kinase (PI3K) in human fetal undifferentiated cells induces morphological and functional endocrine differentiation. This is associated with an increase in mRNA levels of insulin, glucagon, and somatostatin, as well as an increase in the insulin protein content and secretion response to secretagogues. Blockade of PI3K also increases the proportion of pluripotent precursor cells coexpressing multiple hormones and the total number of terminally differentiated cells originating from these precursor cells.
    Type: Grant
    Filed: May 26, 1999
    Date of Patent: July 2, 2002
    Assignee: The Regents of the University of California
    Inventors: Andrezej Ptasznik, Alberti Hayek, Gillian M. Beattie