Patents by Inventor Andries P. Bruins

Andries P. Bruins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemical noise reduction for mass spectrometry
    Patent number: 8030610
    Abstract: In various aspects, the present teachings provide systems and methods for reducing chemical noise in a mass spectrometry instrument that use a neutral chemical reagent and one or more mass filters to reduce interfering chemical background ion signals that are generated by ionization sources of mass spectrometers. In various embodiments, the neutral chemical reagent belongs to the class of organic chemical species containing a disulfide functionality.
    Type: Grant
    Filed: March 25, 2009
    Date of Patent: October 4, 2011
    Assignee: DH Technologies Development Pte. Ltd.
    Inventors: Xinghua Guo, Andries P. Bruins, Tom Covey
  • Chemical Noise Reduction For Mass Spectrometry
    Publication number: 20090256073
    Abstract: In various aspects, the present teachings provide systems and methods for reducing chemical noise in a mass spectrometry instrument that use a neutral chemical reagent and one or more mass filters to reduce interfering chemical background ion signals that are generated by ionization sources of mass spectrometers. In various embodiments, the neutral chemical reagent belongs to the class of organic chemical species containing a disulfide functionality.
    Type: Application
    Filed: March 25, 2009
    Publication date: October 15, 2009
    Applicants: MDS INC., APPLERA CORPORATION
    Inventors: Xinghua Guo, Andries P. Bruins, Tom Covey
  • Chemical noise reduction for mass spectrometry
    Patent number: 7528365
    Abstract: In various aspects, the present teachings provide systems and methods for reducing chemical noise in a mass spectrometry instrument that use a neutral chemical reagent and one or more mass filters to reduce interfering chemical background ion signals that are generated by ionization sources of mass spectrometers. In various embodiments, the neutral chemical reagent belongs to the class of organic chemical species containing a disulfide functionality.
    Type: Grant
    Filed: February 7, 2007
    Date of Patent: May 5, 2009
    Assignees: Applera Corporation, MDS Inc.
    Inventors: Xinghua Guo, Andries P. Bruins, Tom Covey
  • Ion spray apparatus and method
    Patent number: 4861988
    Abstract: A device for interfacing between a microbore liquid chromatograph and a mass analyser. In such a device, liquid from the liquid chromatograph is sprayed through a stainless steel capillary tube into the atmospheric pressure ionization chamber of a mass spectrometer. A voltage of e.g., plus or minus 3 KV is applied to the stainless steel tube, and a nebulizing gas, e.g. nitrogen, is directed at high velocity past the tube tip through another tube encircling the stainless steel tube. The combination of the nebulizing gas and the electric potential disperses the liquid at room temperature into a fine mist providing an increased and more stable ion signal without thermal decomposition of the compounds being analysed.
    Type: Grant
    Filed: September 30, 1987
    Date of Patent: August 29, 1989
    Assignee: Cornell Research Foundation, Inc.
    Inventors: John D. Henion, Thomas R. Covey, Andries P. Bruins