Abstract: Various approaches enable real-time data encryption using an encryption profile that enables a customer to specify the type of data to encrypt and the encryption keys to use when encrypting the data. A profile editor that a customer (e.g., a customer of a content provider) can use to create and manage encryption profiles that can be used to encrypt data can be provided. A profile editor or set of request parameters can allow customers to configure content distributions and associate encryption keys with a profile to encrypt user sensitive data. A customer can select, define, and/or modify the encryption options or other configuration settings for a profile. Once set, the profile can be used to securely ingest user-submitted data to customers' web servers. For example, a request can be analyzed to determine data fields of the request. Based on one or more profiles associated with the customer, the data in those fields can be encrypted with the appropriate encryption key per the profiles.