Abstract: Information about a protein is produced by a number of steps including: Developing a specification of how local descriptors of protein structure are defined. Developing a local descriptors of protein structure database including calculated descriptors. Developing a definition of inter-descriptor similarity measure. Developing a local descriptors of protein structure class database of descriptors organized by their similarity. Producing information about any protein by analyzing said protein using the local descriptors of protein structure class database of descriptors organized by their similarity.