Abstract: A reinforcing and scaling construction for a bioprinted tissue model, which comprises a casing and sealing bioink, the casing comprising an inner module comprising a casing base (1) and a perforated cover (2), and an outer module comprising a container (3) comprising technological valves (5), an outer cover (4) and plugs (6) for technological valves (5). The invention also relates to a method for assembling the reinforcing and sealing construction.

Abstract: A method For manuFacturing a perFusable three-dimensional tissue model, containing therein a channel distributed across its entire structure, enabling the Flow oF Fluids, wherein bioprinting a vascular system with the extrusive method using bioink, the walls opening and closing the channel in its upper part being printed parallel to the channel axis, and bioprinting oF the model body with the extrusive method using bioink, the bioink For printing the body being diFFerent From the bioink used For bioprinting the vessels, placing the resulting system in an incubator, in a temperature in which bioink For printing the vascular system undergoes melt, removing the bioink, optionally, causing growth in the channel by means oF cells in a medium, wherein, the cross-section oF the channel being the same as the cross-section oF native vessels present in a living organism. The inventions relates to a bionic model with a perFusable system.

Abstract: A detergent-free decellularized ECM preparation method, a detergent-free decellularized ECM in a powder form and in a liquid form, a method of preparation of a primary bioink, the primary bioink, a method of preparation of a vascular bioink, the vascular bioink, a three dimensional structure including the primary bioink and/or the vascular bioink and a method of preparation of the three-dimensional structure.

Abstract: The invention relates to a system for connecting a bionic organ to a vascular graft and a method for connecting a bionic organ to a vascular graft under ex vivo conditions. Once connected, the vascular graft is situated within the bionic organ, and the stent is situated internally to the vascular graft and the bionic organ.

Abstract: The invention relates to a medium for storing isolated pancreatic islets and a method for storing isolated pancreatic islets. Such a medium is suitable for storing pancreatic islets both at physiological temperature and refrigerated.

Abstract: The invention relates to a system for storing or cultivating of an organ or a tissue model, and to a use thereof. The system is designed for verifying the functioning of a harvested organ or a tissue model and allows for treating it.

Abstract: A detergent-free decellularized ECM preparation method, a detergent-free decellularized ECM in a powder form and in a liquid form, a method of preparation of a primary bioink, the primary bioink, a method of preparation of a vascular bioink, the vascular bioink, a three dimensional structure including the primary bioink and/or the vascular bioink and a method of preparation of the three-dimensional structure.