Patents by Inventor Andrzej Gardas

Andrzej Gardas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7049124
    Abstract: The present invention relates to the isolation, purification and characterization of a hyaluronidase which derives from the tropical leech Hirudinaria manillensis. Therefore, according to this invention, the enzyme was called “manillase”. The invention is furthermore concerned with the recombinant method of production of manillase which includes the disclosure of DNA and amino acid sequences as well as of expression vectors and host systems. Finally, the invention relates to the use of manillase for therapeutic purposes, for example, for the treatment of myocardial diseases, thrombotic events and tumors.
    Type: Grant
    Filed: June 6, 2000
    Date of Patent: May 23, 2006
    Assignee: Merck Patent GmbH
    Inventors: Maria Kordowicz, Detlef Gussow, Uwe Hofmann, Tadeusz Pacuszka, Andrzej Gardas