Patents by Inventor Andrzej Myc

Andrzej Myc has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190022200
    Abstract: The present invention provides methods and compositions for the stimulation of immune responses. In particular, the present invention provides nanoemulsion compositions and methods of using the same for the induction of immune responses (e.g., innate and adaptive immune responses (e.g., for generation of host immunity against an environmental pathogen)). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications.
    Type: Application
    Filed: May 21, 2018
    Publication date: January 24, 2019
    Inventors: Andrzej Myc, Ilona Kryczek, James R. Baker, JR.
  • Patent number: 10138279
    Abstract: The present invention relates to methods and compositions for stimulating an immune response. Specifically, the present invention provides methods of inducing an immune response to bacteria of the genus Bacillus (e.g., Bacillus anthracis) in a subject (e.g., a human subject) and compositions useful in such methods (e.g., a nanoemulsion comprising Bacillus anthracis or an immunogenic portion thereof). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination) and research applications.
    Type: Grant
    Filed: April 13, 2007
    Date of Patent: November 27, 2018
    Assignee: Regents of the University of Michigan
    Inventors: James R. Baker, Jr., Anna Bielinska, Andrzej Myc
  • Patent number: 9974844
    Abstract: The present invention provides methods and compositions for the stimulation of immune responses. In particular, the present invention provides nanoemulsion compositions and methods of using the same for the induction of immune responses (e.g., innate and adaptive immune responses (e.g., for generation of host immunity against an environmental pathogen)). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: May 22, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Andrzej Myc, Ilona Kryczek, James R. Baker, Jr.
  • Patent number: 9839685
    Abstract: The present invention relates to methods and compositions for the stimulation of immune responses. Specifically, the present invention provides methods of inducing an immune response to human immunodeficiency virus (HIV) in a subject (e.g., a human subject) and compositions useful in such methods (e.g., a nanoemulsion comprising HIV or antigenic portion thereof).
    Type: Grant
    Filed: April 13, 2007
    Date of Patent: December 12, 2017
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: James R. Baker, Jr., Anna Bielinska, Andrzej Myc
  • Publication number: 20150306238
    Abstract: The present invention relates to bacteria-targeting nanoparticles and related methods of use. In particular, the present invention relates to dendrimer nanoparticles conjugated with Vancomycin and/or Polymixin (e.g., Polymixin B, Polymixin E). In certain embodiments, such dendrimer nanoparticles are used to sequester and/or identify bacteria (e.g., Gram-positive bacteria and/or Gram-negative bacteria), screen liquid samples (e.g., water samples, food samples, pharmaceutical samples, blood samples, blood platelet samples, etc.) for the presence of bacteria (e.g., Gram-positive bacteria and/or Gram-negative bacteria), treat disorders associated with bacteria (e.g., Gram-positive bacteria and/or Gram-negative bacteria), and/or identify, sequester, and remove bacteria (e.g., Gram-positive bacteria and/or Gram-negative bacteria) from a liquid sample (e.g., water sample, food sample, pharmaceutical sample, blood sample, blood platelet sample, etc.).
    Type: Application
    Filed: November 27, 2013
    Publication date: October 29, 2015
    Inventors: James R. Baker, Seok Ki Choi, Andrzej Myc
  • Publication number: 20150266933
    Abstract: The present invention relates to methods and compositions for stimulating an immune response. Specifically, the present invention provides methods of inducing an immune response to bacteria of the genus Bacillus (e.g., Bacillus anthracis) in a subject (e.g., a human subject) and compositions useful in such methods (e.g., a nanoemulsion comprising Bacillus anthracis or an immunogenic portion thereof). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination) and research applications.
    Type: Application
    Filed: April 13, 2007
    Publication date: September 24, 2015
    Applicant: Regents of the University of Michigan
    Inventors: James R. Baker, JR., Anna Bielinska, Andrzej Myc
  • Patent number: 8771731
    Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.
    Type: Grant
    Filed: August 18, 2006
    Date of Patent: July 8, 2014
    Assignee: The Regents of the University of Michigan
    Inventors: James R. Baker, Jr., Tarek Hamouda, Amy Shih, Andrzej Myc
  • Publication number: 20130273113
    Abstract: The present invention provides methods and compositions for the stimulation of immune responses. In particular, the present invention provides nanoemulsion compositions and methods of using the same for the induction of immune responses (e.g., immunologic cell death/apoptosis (e.g., for the induction of innate and/or adaptive immune responses)). Compositions and methods of the invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., for infectious disease, cancer, autoimmunity, and/or tissue injury (e.g., via alteration of host immune responses))) and research applications.
    Type: Application
    Filed: March 15, 2013
    Publication date: October 17, 2013
    Applicant: The Regents of the University of Michigan
    Inventors: James R. Baker, JR., Paul Makidon, Andrzej Myc
  • Patent number: 8236335
    Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: August 7, 2012
    Assignee: The Regents of the University of Michigan
    Inventors: James R. Baker, Jr., Tarek Hamouda, Amy Shih, Andrzej Myc
  • Patent number: 8232320
    Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: July 31, 2012
    Assignee: The Regents of the University of Michigan
    Inventors: James R. Baker, Jr., Tarek Hamouda, Amy Shih, Andrzej Myc
  • Publication number: 20120141526
    Abstract: The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides methods and compositions for the use of nanoemulsion compounds as mucosal adjuvants to induce immunity against environmental pathogens. Accordingly, in some embodiments, the present invention provides nanoemulsion vaccines comprising a nanoemulsion and an inactivated pathogen or protein derived from the pathogen. The present invention thus provides improved vaccines against a variety of environmental and human-released pathogens.
    Type: Application
    Filed: October 30, 2007
    Publication date: June 7, 2012
    Applicant: The Regents of the University of Michigan
    Inventors: James R. Baker, Anna Bielinska, Andrzej Myc
  • Publication number: 20110280911
    Abstract: The present invention provides methods and compositions for the stimulation of immune responses. In particular, the present invention provides nanoemulsion compositions and methods of using the same for the induction of immune responses (e.g., innate and adaptive immune responses (e.g., for generation of host immunity against an environmental pathogen)). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications.
    Type: Application
    Filed: November 17, 2009
    Publication date: November 17, 2011
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Andrzej Myc, Ilona Kryczek, James R. Baker, JR.
  • Publication number: 20110091556
    Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs. In particular, decreased pathogenic organism infectivity, morbidity, and mortality is accomplished by contacting the pathogenic organism with an oil-in-water nanoemulsion comprising an oil, an organic solvent, and a surfactant dispersed in an aqueous phase.
    Type: Application
    Filed: August 18, 2006
    Publication date: April 21, 2011
    Inventors: James R. Baker, JR., Tarek Hamouda, Amy Shih, Andrzej Myc
  • Publication number: 20110070306
    Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.
    Type: Application
    Filed: August 18, 2006
    Publication date: March 24, 2011
    Inventors: James R. Baker, JR., Tarek Hamouda, Amy Shih, Andrzej Myc
  • Patent number: 7767216
    Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs. In particular, decreased pathogenic organism infectivity, morbidity, and mortality is accomplished by contacting the pathogenic organism with an oil-in-water nanoemulsion comprising an oil, an organic solvent, and a surfactant dispersed in an aqueous phase.
    Type: Grant
    Filed: December 29, 2000
    Date of Patent: August 3, 2010
    Assignee: The Regents of the University of Michigan
    Inventors: James R. Baker, Jr., Tarek Hamouda, Amy Shih, Andrzej Myc
  • Patent number: 7655252
    Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.
    Type: Grant
    Filed: June 25, 2002
    Date of Patent: February 2, 2010
    Assignee: The Regents of the University of Michigan
    Inventors: James R. Baker, Jr., Tarek Hamouda, Amy Shih, Andrzej Myc
  • Publication number: 20100003330
    Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.
    Type: Application
    Filed: June 25, 2002
    Publication date: January 7, 2010
    Applicant: The Regents of the University of Michigan
    Inventors: James R. Baker, JR., Tarek Hamouda, Amy Shih, Andrzej Myc
  • Publication number: 20090143476
    Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.
    Type: Application
    Filed: October 30, 2007
    Publication date: June 4, 2009
    Applicant: Regents of the University of Michigan
    Inventors: James R. Baker, JR., Tarek Hamouda, Amy Shih, Andrzej Myc
  • Publication number: 20090143477
    Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.
    Type: Application
    Filed: October 30, 2007
    Publication date: June 4, 2009
    Applicant: Regents of the University of Michigan
    Inventors: James R. Baker, JR., Tarek Hamouda, Amy Shih, Andrzej Myc
  • Publication number: 20090068225
    Abstract: The present invention relates to methods and compositions for stimulating an immune response. Specifically, the present invention provides methods of inducing an immune response to an orthopox virus (e.g., vaccinia virus) in a subject (e.g., a human subject) and compositions useful in such methods (e.g., a nanoemulsion comprising vaccinia virus). Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination) and research applications.
    Type: Application
    Filed: August 14, 2008
    Publication date: March 12, 2009
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHGAN
    Inventors: James R. Baker, JR., Anna Bielinska, Andrzej Myc