Patents by Inventor Andrzej W. Lipkowski

Andrzej W. Lipkowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of a peptide and an analgesic pharmaceutical agent
    Patent number: 9486493
    Abstract: Inflammation caused by disease states such as rheumatism, gout, neurodegeneration and tumours result in the increased effectiveness of the opioid peptide biphalin or its analogues, due likely to the increased permeability of the “blood-brain barrier”, due to which it becomes possible to use the opioid peptide to produce a new analgesic for use during inflammation caused by rheumatism, gout, neurodegeneration, post-surgical or post-accidental trauma or tumours.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: November 8, 2016
    Inventors: Andrzej W. Lipkowski, Daniel Carr, Aleksandra Misicka-Kesik, Piotr Kosson, Anna Klinowiecka
  • USE OF A PEPTIDE AND AN ANALGESIC PHARMACEUTICAL AGENT
    Publication number: 20100273715
    Abstract: Inflammation caused by disease states such as rheumatism, gout, neurodegeneration and tumours result in the increased effectiveness of the opioid peptide biphalin or its analogues, due likely to the increased permeability of the “blood-brain barrier”, due to which it becomes possible to use the opioid peptide to produce a new analgesic for use during inflammation caused by rheumatism, gout, neurodegeneration, post-surgical or post-accidental trauma or tumours.
    Type: Application
    Filed: March 7, 2008
    Publication date: October 28, 2010
    Inventors: Andrzej W. Lipkowski, Daniel Carr, Aleksandra Misicka-Kesik, Piotr Kosson, Anna Klinowiecka
  • Antimicrobial compounds
    Patent number: 7723467
    Abstract: The invention features an antimicrobial composition comprising a substance P peptide and methods of inhibiting growth of a microorganism by contacting the microorganism with a substance P peptide. Bacterial and fungal pathogens are inhibited by the substance P compositions.
    Type: Grant
    Filed: July 13, 2005
    Date of Patent: May 25, 2010
    Assignee: New England Medical Center Hospitals, Inc.
    Inventors: Andrzej W. Lipkowski, Daniel B. Carr
  • Novel Chimeric Analgesic Peptides
    Publication number: 20090298755
    Abstract: The present invention provides a novel chimeric peptide containing an opioid peptide moiety and a nociceptive peptide moiety for producing analgesia.
    Type: Application
    Filed: March 28, 2007
    Publication date: December 3, 2009
    Inventors: Daniel B. Carr, Andrzej W. Lipkowski, Richard Kream, Aleksandra Misicka-Kesik
  • Drug delivery composition
    Patent number: 6913760
    Abstract: The invention provides a drug delivery compositions and methods for treating pain. A drug delivery composition contains a polymer and at least two drugs sucha as an analgesic agent and an anesthetic agent.
    Type: Grant
    Filed: August 6, 2002
    Date of Patent: July 5, 2005
    Assignee: New England Medical Hospitals, Inc.
    Inventors: Daniel B. Carr, Andrzej W. Lipkowski, Donald L. Wise, Vasif Hasirci
  • Substituted guanidines and the use thereof
    Patent number: 6875759
    Abstract: A method for the treatment of cancer and pain in an animal subject is disclosed, comprising administering to said animal in need of such treatment an effective amount of a compound of formula I: wherein R1-R6 are defined herein. Pharmaceutical compositions comprising one or more compounds of formula I and a pharmaceutically acceptable carrier are also disclosed.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: April 5, 2005
    Assignee: Kadmus Pharmaceuticals
    Inventors: Andrzej W. Lipkowski, Kelvin Gee
  • Chimeric analgesic peptides
    Patent number: 6759520
    Abstract: The present invention provides a novel chimeric peptide containing an opioid peptide moiety and a nociceptive peptide moiety for producing analgesia.
    Type: Grant
    Filed: October 28, 1999
    Date of Patent: July 6, 2004
    Assignee: The New England Medical Center Hospitals, Inc.
    Inventors: Daniel B. Carr, Andrzej W. Lipkowski, Richard Kream, Aleksandra Misicka-Kesik
  • Drug delivery composition
    Publication number: 20030170288
    Abstract: The invention provides a drug delivery compositions and methods for treating pain. A drug delivery composition contains a polymer and at least two drugs sucha as an analgesic agent and an anesthetic agent.
    Type: Application
    Filed: August 6, 2002
    Publication date: September 11, 2003
    Inventors: Daniel B. Carr, Andrzej W. Lipkowski, Donald L. Wise, Vasif Hasirci
  • Novel antimicrobial compounds
    Publication number: 20030032599
    Abstract: The invention features an antimicrobial composition comprising a substance P peptide and methods of inhibiting growth of a microorganism by contacting the microorganism with a substance P peptide. Bacterial and fungal pathogens are inhibited by the substance P compositions.
    Type: Application
    Filed: November 20, 2001
    Publication date: February 13, 2003
    Inventors: Andrzej W. Lipkowski, Daniel B. Carr
  • Substituted pyrroles with opioid receptor activity
    Patent number: 4649200
    Abstract: Substituted pyrroles of the formula: ##STR1## are disclosed wherein R.sup.1 is (C.sub.1 -C.sub.5)alkyl, C.sub.3 -C.sub.6 (cycloalkyl) alkyl, C.sub.5 -C.sub.7 (cycloalkenyl)alkyl, aryl, aralkyl, trans-(C.sub.4 -C.sub.5) alkenyl, allyl or furan-2-ylalkyl; R.sup.2 is H or OH, R.sup.3 is H, (C.sub.1 -C.sub.5)alkyl or (C.sub.1 -C.sub.5)alkanoyl and R.sup.4 is H or (C.sub.1 -C.sub.5) alkyl; as well as the pharmaceutically-acceptable salts thereof. These compounds are useful as analgesics and/or as selective kappa-opioid antagonists.
    Type: Grant
    Filed: May 8, 1986
    Date of Patent: March 10, 1987
    Assignee: Regents of the University of Minnesota
    Inventors: Philip S. Portoghese, Andrzej W. Lipkowski