Patents by Inventor Andrzej Zatorski

Andrzej Zatorski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • C-nucleoside isostere of nicotinamide adenine dinucleotide, analogs thereof and use as anti-cancer agent
    Patent number: 5658890
    Abstract: This invention provides a compound having the structure: ##STR1## wherein each R.sub.1, R.sub.2, R.sub.3, and R.sub.4 is independently fluorine, OH or H; Z is O, CH.sub.2 or CF.sub.2 ; each Y is independently OH or F; X.sub.7 is N or CH, X.sub.8 is NH, S or Se; and W is C or N, wherein when W is C, the dashed line (---) represents a double bond and X.sub.9 is N or CH, and wherein when W is N, the dashed line (---) represents a single bond and X.sub.9 is S or Se, or the dashed line (---) represents a double bond and X.sub.9 is N or CH.This invention also provides a pharmaceutical composition comprising the compounds and methods of treating a mammal having an inosine monophosphate dehydrogenase associated disorder.
    Type: Grant
    Filed: March 30, 1995
    Date of Patent: August 19, 1997
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Krysztof W. Pankiewicz, Kyoichi A. Watanabe, Andrzej Zatorski