Abstract: A shoe sole for an article of footwear is described herein. The shoe sole extends in a longitudinal direction from a heel region, through a midfoot region, to a forefoot region. The sole includes a midsole and an outsole. The midsole has an upper surface for attachment to at least one of an insole and a shoe upper, and a lower surface disposed opposite the upper surface. The midsole includes a forefoot cushioning element, a midfoot cushioning element, and a heel cushioning element. The outsole is disposed along the lower surface of the midsole and defines a ground-contacting surface of the sole. The sole has an upwardly convex bottom profile such that an impact region of the sole is defined within the midfoot region, and the midfoot cushioning element is disposed within the midfoot region and directly above the impact region of the sole.