Patents by Inventor Andy J. Jennings

Andy J. Jennings has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR MICROGLIA REPLACEMENT THERAPY
    Publication number: 20230081264
    Abstract: The present disclosure provides methods and compositions for microglia replacement therapy in a subject in need thereof. In some cases, the method involves administering myeloid cells to the central nervous system of a subject. In some cases, the myeloid cells are derived from embryonic or extraembryonic tissue. In some cases, the myeloid cells are genetically modified. The genetic modification may include a colony stimulating factor 1 receptor (CSF1R) variant that is resistant to a CSF1R inhibitor, yet retains sensitivity to its ligand (e.g., CSF1, IL34).
    Type: Application
    Filed: September 10, 2019
    Publication date: March 16, 2023
    Inventors: Frederick Christian Bennett, Peter A. Thompson, Mariko L. Bennett, Andy J. Jennings