Patents by Inventor Aneel K. Aggarwal

Aneel K. Aggarwal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of modulating bromodomains
    Publication number: 20120028912
    Abstract: The present invention features compounds useful for and methods for preventing or inhibiting the binding of bromodomains to acetyl-lysine residues of proteins and methods for treating HIV infection and HIV related disease.
    Type: Application
    Filed: November 2, 2009
    Publication date: February 2, 2012
    Inventors: Ming-Ming Zhou, Aneel K. Aggarwal, Melanie Ott, Eric Verdin
  • ZA loops of bromodomains
    Patent number: 7919276
    Abstract: The present invention provides the structural determination of a bromodomain determined by NMR spectroscopy. The present invention also provides a binding partner for the bromodomain. In addition, the present invention provides methodology for related drug discovery using high throughput drug screening or structure based rational drug design using the three-dimensional data.
    Type: Grant
    Filed: February 22, 2000
    Date of Patent: April 5, 2011
    Assignee: Mount Sinai School of Medicine
    Inventors: Ming-Ming Zhou, Aneel K. Aggarwal
  • ZA loops of bromodomains
    Patent number: 7589167
    Abstract: The present invention provides the structural determination of a bromodomain determined by NMR spectroscopy. The present invention also provides binding partners for the bromodomain. The present invention further provides the structural determination of the Tat-P/CAF binding complex determined by NMR spectroscopy. In addition, the present invention provides methodology for related drug discovery using high throughput drug screening or structure based rational drug design using the three-dimensional data.
    Type: Grant
    Filed: February 16, 2001
    Date of Patent: September 15, 2009
    Assignees: J. David Gladstone Institutes, Mt. Sinai School of Medicine
    Inventors: Ming-Ming Zhou, Aneel K. Aggarwal, Eric Verdin, Melanie Ott
  • Methods of identifying modulators of bromodomains
    Publication number: 20040043378
    Abstract: The present invention provides the structural determination of a bromodomain determined by NMR spectroscopy. The present invention also provides binding partners for the bromodomain. The present invention further provides the structural determination of the Tat-P/CAF binding complex determined by NMR spectroscopy. In addition, the present invention provides methodology for related drug discovery using high throughput drug screening or structure based rational drug design using the three-dimensional data.
    Type: Application
    Filed: February 16, 2001
    Publication date: March 4, 2004
    Inventors: Ming-Ming Zhou, Aneel K. Aggarwal, Eric Verdin, Melanie Ott
  • Methods of identifying modulators of bromodomains
    Publication number: 20040009613
    Abstract: The present invention provides the structural determination of a bromodomain determined by NMR spectroscopy. The present invention also provides binding partners for the bromodomain. The present invention further provides the structural determination of the Tat-P/CAF binding complex determined by NMR spectroscopy. In addition, the present invention provides methodology for related drug discovery using high throughput drug screening or structure based rational drug design using the three-dimensional data.
    Type: Application
    Filed: July 31, 2002
    Publication date: January 15, 2004
    Inventors: Ming-Ming Zhou, Aneel K. Aggarwal, Eric Verdin, Melanie Ott