Abstract: The invention concerns a dispenser, in particular for semi-solid or liquid systems, with a housing to hold a dispenser unit which is formed by a storage container, a metering unit (3) connected therewith via which the substance can be output in defined doses and an activation mechanism (4) which can activate the metering unit (3) to output a dose of substance, where the dispenser unit is held via a reservoir holder (5) in the housing (1). Known dispensers have the disadvantage that the dispenser unit is not held securely against tipping. The invention avoids this in that the storage container (2) is formed with a lower volume area (2?) and an upper volume area (2?) which to form the reservoir holder between its upper and lower end has a constricted shoulder area (9) with an inwardly angled setting surface, where the housing (1) has a corresponding support surface (10) to support the setting surface.