Abstract: This invention is related to an oral pharmaceutical composition that contains a cholinergic agent, a natural plant alkaloid in particular, selected from the group of lobeline, anabasine, cytisine, galantamine or their acceptable salts, in the form of tablets and capsules. The excipients of the developed oral composition include cellulose powder, calcium sulphate, silica colloidal and magnesium stearate, the total content of cellulose powder and calcium sulphate dihydrate being from 64.5 to 97.5% of the mass of the dosage form and at least 90% of the alkaloid particles being ?100 ?m. The oral composition contains also at least one biologically active amino acid selected from: L-carnitine, tryptophan or a combination of them.

Abstract: This invention is related to an oral pharmaceutical composition that contains a cholinergic agent, a natural plant alkaloid in particular, selected from the group of lobeline, anabasine, cytisine, galantamine or their acceptable salts, in the form of tablets and capsules. The excipients of the developed oral composition include cellulose powder, calcium sulphate, silica colloidal and magnesium stearate, the total content of cellulose powder and calcium sulphate dihydrate being from 64.5 to 97.5% of the mass of the dosage form and at least 90% of the alkaloid particles being ?100 ?m. The oral composition contains also at least one biologically active amino acid selected from: L-carnitine, tryptophan or a combination of them.