Patents by Inventor Angela Belcher

Angela Belcher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9550809
    Abstract: A dodecamer peptide, and its modified variant, having a repeating glycine-lysine sequence was created and found to bind with high affinity to oxide surfaces and certain activated polymeric surfaces. Reversible binding characteristics of the peptides were demonstrated. The peptides were integrated with proteins, cells and fusion proteins to provide attachment of the proteins, cells and fusion proteins to solid material structures. The peptides can be used to functionalize surfaces of components within mechanical, biomechanical, micro fluidic, electronic, bioelectronic, bio-optical, and biochemical devices. Experiments were carried out to assess functionalization and reusability of a suspended mass resonator's cantilever.
    Type: Grant
    Filed: September 23, 2013
    Date of Patent: January 24, 2017
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Erik Mark Krauland, Stephen Kottmann, Roberto Juan Barbero, Angela Belcher
  • Patent number: 9527741
    Abstract: Embodiments described herein generally relate to compositions comprising a graphene oxide species. In some embodiments, the compositions advantageously have relatively high oxygen content, even after annealing.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: December 27, 2016
    Assignee: Massachusetts Institute of Technology
    Inventors: Priyank Vijaya Kumar, Neelkanth M. Bardhan, Angela Belcher, Jeffrey Grossman
  • Publication number: 20150259381
    Abstract: A dodecamer peptide, and its modified variant, having a repeating glycine-lysine sequence was created and found to bind with high affinity to oxide surfaces and certain activated polymeric surfaces. Reversible binding characteristics of the peptides were demonstrated. The peptides were integrated with proteins, cells and fusion proteins to provide attachment of the proteins, cells and fusion proteins to solid material structures. The peptides can be used to functionalize surfaces of components within mechanical, biomechanical, micro fluidic, electronic, bioelectronic, bio-optical, and biochemical devices. Experiments were carried out to assess functionalization and reusability of a suspended mass resonator's cantilever.
    Type: Application
    Filed: September 23, 2013
    Publication date: September 17, 2015
    Inventors: Erik Mark Krauland, Stephen Kottmann, Roberto Juan Barbero, Angela Belcher
  • Patent number: 8986999
    Abstract: Methods and apparatuses for encapsulating inorganic micro- or nanostructures within polymeric microgels are described. In various embodiments, viruses are encapsulated with microgels during microgel formation. The viruses can provide a template for in situ synthesis of the inorganic structures within the microgel. The inorganic structures can be distributed substantially homogeneously throughout the microgel, or can be distributed non-uniformly within the microgel. The inventive microgel compositions can be used for a variety of applications including electronic devices, biotechnological devices, fuel cells, display devices and optical devices.
    Type: Grant
    Filed: February 7, 2014
    Date of Patent: March 24, 2015
    Assignees: Massachusetts Institute of Technology, President and Fellows of Harvard University
    Inventors: Yoon Sung Nam, Angela Belcher, Andrew Parsons Magyar, Daeyeon Lee, Jin-Woong Kim, David Weitz
  • Publication number: 20140329002
    Abstract: Embodiments described herein generally relate to compositions comprising a graphene oxide species. In some embodiments, the compositions advantageously have relatively high oxygen content, even after annealing.
    Type: Application
    Filed: May 5, 2014
    Publication date: November 6, 2014
    Applicant: Massachusetts Institute of Technology
    Inventors: Priyank Vijaya Kumar, Neelkanth M. Bardhan, Angela Belcher, Jeffrey Grossman
  • Patent number: 8865347
    Abstract: Alloys of tunable compositions and corresponding optical, electrical and mechanical properties are described. Also described are their uses in optoelectronic devices and material interfaces.
    Type: Grant
    Filed: February 27, 2007
    Date of Patent: October 21, 2014
    Assignee: Siluria Technologies, Inc.
    Inventors: Evelyn Hu, Angela Belcher, Xina Quan
  • Publication number: 20140151912
    Abstract: Methods and apparatuses for encapsulating inorganic micro- or nanostructures within polymeric microgels are described. In various embodiments, viruses are encapsulated with microgels during microgel formation. The viruses can provide a template for in situ synthesis of the inorganic structures within the microgel. The inorganic structures can be distributed substantially homogeneously throughout the microgel, or can be distributed non-uniformly within the microgel. The inventive microgel compositions can be used for a variety of applications including electronic devices, biotechnological devices, fuel cells, display devices and optical devices.
    Type: Application
    Filed: February 7, 2014
    Publication date: June 5, 2014
    Applicants: President and Fellows of Harvard college, Massachusetts Institute of Technology
    Inventors: Yoon Sung Nam, Angela Belcher, Daeyeon Lee, Jin-Woong Kim, David Weitz
  • Patent number: 8685323
    Abstract: Methods and apparatuses for encapsulating inorganic micro- or nanostructures within polymeric microgels are described. In various embodiments, viruses are encapsulated with microgels during microgel formation. The viruses can provide a template for in situ synthesis of the inorganic structures within the microgel. The inorganic structures can be distributed substantially homogeneously throughout the microgel, or can be distributed non-uniformly within the microgel. The inventive microgel compositions can be used for a variety of applications including electronic devices, biotechnological devices, fuel cells, display devices and optical devices.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: April 1, 2014
    Assignees: Massachusetts Institute of Technology, President and Fellows of Harvard College
    Inventors: Yoon Sung Nam, Angela Belcher, Andrew Magyar, Daeyeon Lee, Jin-Woong Kim, David Weitz
  • Publication number: 20140030697
    Abstract: The present invention, in some aspects, provides methods, reagents, and kits for the functionalization of proteins on the surface of viral particles, for example, of bacteriophages, using sortase-mediated transpeptidation reactions. Some aspects of this invention provide methods for the conjugation of an agent, for example, a detectable label, a binding agent, a click-chemistry handle, or a small molecule to a surface protein of a viral particle. Kits comprising reagents useful for the generation of functionalized viral particles are also provided, as are precursor proteins that comprise a sortase recognition motif, and viral particles comprising such precursor proteins. Nucleic acids encoding viral proteins comprising a sortase recognition motif and expression vectors comprising such nucleic acids are also provided.
    Type: Application
    Filed: June 14, 2013
    Publication date: January 30, 2014
    Applicants: Massachusetts Institute of Technology, Whitehead Institute for Biomedical Research
    Inventors: Hidde L. Ploegh, Gaelen Hess, Carla Guimaraes, Angela Belcher
  • Patent number: 8569226
    Abstract: A dodecamer peptide, and its modified variant, having a repeating glycine-lysine sequence was created and found to bind with high affinity to oxide surfaces and certain activated polymeric surfaces. Reversible binding characteristics of the peptides were demonstrated. The peptides were integrated with proteins, cells and fusion proteins to provide attachment of the proteins, cells and fusion proteins to solid material structures. The peptides can be used to functionalize surfaces of components within mechanical, in mechanical, biomechanical, micro fluidic, electronic, bioelectronic, bio-optical, and biochemical devices. Experiments were carried out to assess functionalization and reusability of a suspended mass resonator's cantilever.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: October 29, 2013
    Assignee: Massachusetts Institute of Technology
    Inventors: Eric Mark Krauland, Stephen Kottmann, Roberto Juan Barbero, Angela Belcher
  • Patent number: 8431506
    Abstract: A method of making a metal oxide nanoparticle comprising contacting an aqueous solution of a metal salt with an oxidant. The method is safe, environmentally benign, and uses readily available precursors. The size of the nanoparticles, which can be as small as 1 nm or smaller, can be controlled by selecting appropriate conditions. The method is compatible with biologically derived scaffolds, such as virus particles chosen to bind a desired material. The resulting nanoparticles can be porous and provide advantageous properties as a catalyst.
    Type: Grant
    Filed: October 25, 2010
    Date of Patent: April 30, 2013
    Assignee: Massachusetts Institute of Technology
    Inventors: Brian Neltner, Angela Belcher
  • Publication number: 20130045514
    Abstract: Carbonic anhydrase can be expressed on a cell surface in a system and method for mineralizing carbon dioxide. The system and method can optionally include a mineralization peptide to facilitate formation of minerals from carbonate ions and divalent metal cations.
    Type: Application
    Filed: August 17, 2011
    Publication date: February 21, 2013
    Inventors: Roberto Barbero, Elizabeth Wood, Angela Belcher
  • Publication number: 20120003629
    Abstract: The present invention includes compositions and methods for selective binding of amino acid oligomers to semiconductor and elemental carbon-containing materials. One form of the present invention is a method for controlling the particle size of the semiconductor or elemental carbon-containing material by interacting an amino acid oligomer that specifically binds the material with solutions that can result in the formation of the material. The same method can be used to control the aspect ratio of the nanocrystal particles of the semiconductor material. Another form of the present invention is a method to create nanowires from the semiconductor or elemental carbon-containing material. Yet another form of the present invention is a biologic scaffold comprising a substrate capable of binding one or more biologic materials, one or more biologic materials attached to the substrate, and one or more elemental carbon-containing molecules attached to one or more biologic materials.
    Type: Application
    Filed: February 8, 2006
    Publication date: January 5, 2012
    Inventors: Angela Belcher, Richard Smalley, Esther Ryan, Seung-Wuk Lee
  • Patent number: 7960721
    Abstract: A light emitting device includes a substrate layer, a first injection contact positioned over the substrate layer, a first dielectric layer positioned over the first injection contact, a light emission layer positioned over the first dielectric layer, a second dielectric layer positioned over the light emission layer and a second injection contact positioned over the second dielectric layer. The light emission layer includes an organic template having binding sites for binding nanoparticles into an array. The wavelength of emitted light is dependent upon the size of the nanoparticles and the pitch of the array. The light emitting device may include a first plurality of binding sites for binding a first set of nanoparticles and a second plurality of binding sites for binding a second set of nanoparticles. The wavelength depends upon a ratio of the first plurality to the second plurality of binding sites.
    Type: Grant
    Filed: February 13, 2008
    Date of Patent: June 14, 2011
    Assignee: Siluria Technologies, Inc.
    Inventors: Angela Belcher, Evelyn Hu, Xina Quan, Hash Pakbaz
  • Publication number: 20110124488
    Abstract: A method of making a metal oxide nanoparticle comprising contacting an aqueous solution of a metal salt with an oxidant. The method is safe, environmentally benign, and uses readily available precursors. The size of the nanoparticles, which can be as small as 1 nm or smaller, can be controlled by selecting appropriate conditions. The method is compatible with biologically derived scaffolds, such as virus particles chosen to bind a desired material. The resulting nanoparticles can be porous and provide advantageous properties as a catalyst.
    Type: Application
    Filed: October 25, 2010
    Publication date: May 26, 2011
    Applicant: Massachusetts Institute of Technology
    Inventors: Brian Neltner, Angela Belcher
  • Publication number: 20110116993
    Abstract: Methods and apparatuses for encapsulating inorganic micro- or nanostructures within polymeric microgels are described. In various embodiments, viruses are encapsulated with microgels during microgel formation. The viruses can provide a template for in situ synthesis of the inorganic structures within the microgel. The inorganic structures can be distributed substantially homogeneously throughout the microgel, or can be distributed non-uniformly within the microgel. The inventive microgel compositions can be used for a variety of applications including electronic devices, biotechnological devices, fuel cells, display devices and optical devices.
    Type: Application
    Filed: September 19, 2008
    Publication date: May 19, 2011
    Applicant: Massachusetts Institute of Technology
    Inventors: Yoon Sung Nam, Angela Belcher, Andrew Magyar, Daeyeon Lee, Jin-Woong Kim, David Weitz
  • Publication number: 20100278892
    Abstract: A dodecamer peptide, and its modified variant, having a repeating glycine-lysine sequence was created and found to bind with high affinity to oxide surfaces and certain activated polymeric surfaces. Reversible binding characteristics of the peptides were demonstrated. The peptides were integrated with proteins, cells and fusion proteins to provide attachment of the proteins, cells and fusion proteins to solid material structures. The peptides can be used to functionalize surfaces of components within mechanical, in mechanical, biomechanical, micro fluidic, electronic, bioelectronic, bio-optical, and biochemical devices. Experiments were carried out to assess functionalization and reusability of a suspended mass resonator's cantilever.
    Type: Application
    Filed: September 19, 2008
    Publication date: November 4, 2010
    Applicant: Massachusetts Institute of Technology
    Inventors: Eric Mark Krauland, Stephen Kottmann, Roberto Juan Barbero, Angela Belcher
  • Publication number: 20100053928
    Abstract: A light emitting device includes a substrate layer, a first injection contact positioned over the substrate layer, a first dielectric layer positioned over the first injection contact, a light emission layer positioned over the first dielectric layer, a second dielectric layer positioned over the light emission layer and a second injection contact positioned over the second dielectric layer. The light emission layer includes an organic template having binding sites for binding nanoparticles into an array. The wavelength of emitted light is dependent upon the size of the nanoparticles and the pitch of the array. The light emitting device may include a first plurality of binding sites for binding a first set of nanoparticles and a second plurality of binding sites for binding a second set of nanoparticles. The wavelength depends upon a ratio of the first plurality to the second plurality of binding sites.
    Type: Application
    Filed: February 13, 2008
    Publication date: March 4, 2010
    Applicant: SILURIA TECHNOLOGIES, INC.
    Inventors: Angela Belcher, Evelyn Hu, Xina Quan, Hash Pakbaz
  • Publication number: 20090305226
    Abstract: Discrete and diffuse defects in a surface are detected. Discrete defects that may compromise the performance may be repaired.
    Type: Application
    Filed: October 19, 2005
    Publication date: December 10, 2009
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Asher Sinensky, Angela Belcher
  • Publication number: 20080213663
    Abstract: Alloys of tunable compositions and corresponding optical, electrical and mechanical properties are described. Also described are their uses in optoelectronic devices and material interfaces.
    Type: Application
    Filed: February 27, 2007
    Publication date: September 4, 2008
    Applicant: CAMBRIOS TECHNOLOGIES CORPORATION
    Inventors: Evelyn Hu, Angela Belcher, Xina Quan