Patents by Inventor Angela Brooks-Wilson

Angela Brooks-Wilson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7897744
    Abstract: The invention provides, in part, the genomic sequence of a putative coronavirus, the SARS virus, and provides novel nucleic acid and amino acid sequences that may be used, for example, for the diagnosis, prophylaxis, or therapy of a variety of SARS virus related disorders.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: March 1, 2011
    Assignee: The Public Health Agency of Canada
    Inventors: Frank Plummer, Heinz Feldmann, Steven Jones, Yan Li, Nathalie Bastien, Robert Conrad Brunham, Angela Brooks-Wilson, Robert Holt, Christopher Upton, Rachel Roper, Caroline Astell, Steven Jones
  • Publication number: 20070298420
    Abstract: Methods and compounds are disclosed for lowering serum LDL levels or serum cholesterol levels, or for reducing the transport of cholesterol from the gut to the blood or the lymph, based on the observation that a gene known as ABC1 is necessary in order for cholesterol to be transported from the intestinal lumen into the bloodstream. A mutant chicken phenotype, known as the WHAM chicken, characterized by low levels of serum LDL and reduced transport of cholesterol, facilitated the discovery of this function of the ABC1 gene. Techniques which act to inhibit ABC1 activity in the cells of the intestinal wall will result in lower serum cholesterol.
    Type: Application
    Filed: November 28, 2006
    Publication date: December 27, 2007
    Inventors: Alan Attie, Mark Cook, Mark Gray-Keller, Michael Hayden, Simon Pimstone, Angela Brooks-Wilson
  • Publication number: 20070258999
    Abstract: The invention provides, in part, the genomic sequence of a putative coronavirus, the SARS virus, and provides novel nucleic acid and amino acid sequences that may be used, for example, for the diagnosis, prophylaxis, or therapy of a variety of SARS virus related disorders.
    Type: Application
    Filed: April 28, 2004
    Publication date: November 8, 2007
    Applicant: THE PUBLIC HEALTH AGENCY OF CANADA
    Inventors: Frank Plummer, Heinz Feldmann, Steven Jones, Yan Li, Nathalie Bastien, Robert Brunham, Angela Brooks-Wilson, Robert Holt, Christopher Upton, Rachel Roper, Caroline Astell, Steven Jones
  • Publication number: 20050136421
    Abstract: The invention features ABC1 nucleic acids and polypeptides for the diagnosis and treatment of abnormal cholesterol regulation. The invention also features methods for identifying compounds for modulating cholesterol levels in an animal (e.g., a human).
    Type: Application
    Filed: April 5, 2004
    Publication date: June 23, 2005
    Inventors: Michael Hayden, Angela Brooks-Wilson, Simon Pimstone
  • Publication number: 20050019765
    Abstract: The invention features methods for treating, preventing or modulating a neurological disease or disorder, or for modulating an anaesthetic or a fertility process by administering compounds that modulate ABCA1 expression or activity. The invention also features methods for identifying compounds useful for such methods.
    Type: Application
    Filed: June 7, 2002
    Publication date: January 27, 2005
    Inventors: Cheryl Wellington, Angela Brooks-Wilson, Michael Hayden