Patents by Inventor Angela D. Wilkins
Angela D. Wilkins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10300106Abstract: An autophagy-inducing compound comprises an autophagy-inducing peptide comprising Beclin 1 peptides immediately N- and C-terminally flanked by moieties R1 and R2, respectively, wherein up to six of said peptide residues may be substituted, R1 and R2 do not naturally flank the Beclin 1 residues, and F270 and F274 are optionally substituted and optionally linked. The compounds may be used to induce autophagy.Type: GrantFiled: September 3, 2015Date of Patent: May 28, 2019Assignee: Board of Regents, The University of Texas SystemInventors: Beth C. Levine, Sanae Shoji-Kawata, Nick V. Grishin, Lisa N. Kinch, Olivier Lichtarge, Angela D. Wilkins
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Patent number: 9886665Abstract: A method, system, and computer program product for event detection using roles and relationships of entities are provided in the illustrative embodiments. A training event and a set of entities participating in the training event are identified in a training data. For a first entity in the set of entities, a first role occupied by the entity in the event is determined. A behavior attribute is assigned to the first role. A relationship of the first role with a second role corresponding to a second entity in the set of entities is determined. An event rule is constructed to detect an event corresponding to the training event in new data and comprising a plurality of roles, behavior attributes, and the relationship. The plurality of roles includes the first role and the second role, and the plurality of behavior attributes includes the behavior attribute assigned to the first role.Type: GrantFiled: December 8, 2014Date of Patent: February 6, 2018Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Ying Chen, Linda H. Kato, Jacques J. Labrie, Meenakshi Nagarajan, William Scott Spangler, Ioana R. Stanoi, Anbu Karani Adikesavan, Benjamin J. Bachman, Lawrence A. Donehower, Olivier Lichtarge, Sam J. Regenbogen, Maria E. Terron-Diaz, Angela D. Wilkins, Curtis R. Pickering
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Patent number: 9720902Abstract: A new information in a language and relating to a subject matter domain is parsed into a constituent set of complete grammatical constructs. In a subset of the complete grammatical constructs, a set of linguistic styles of the language is identified according to a subset of a set of word-style associations related to the language and independent of the subject matter domain. A first weight is assigned to a first linguistic style and a second weight to a second linguistic style from the set of linguistic styles. A first intention information is mapped to the first style using a first style-intention rule, and a second intention information to the second style using a second style-intention rule. A complete grammatical construct in the subset is tagged with the first intention information responsive to a weight associated with the first intention information exceeding an intention selection threshold.Type: GrantFiled: March 16, 2016Date of Patent: August 1, 2017Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Meenakshi Nagarajan, William Scott Spangler, Benjamin J. Bachman, Lawrence A. Donehower, Olivier Lichtarge, Sam J. Regenbogen, Angela D. Wilkins, Curtis R. Pickering
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Publication number: 20160203118Abstract: A new information in a language and relating to a subject matter domain is parsed into a constituent set of complete grammatical constructs. In a subset of the complete grammatical constructs, a set of linguistic styles of the language is identified according to a subset of a set of word-style associations related to the language and independent of the subject matter domain. A first weight is assigned to a first linguistic style and a second weight to a second linguistic style from the set of linguistic styles. A first intention information is mapped to the first style using a first style-intention rule, and a second intention information to the second style using a second style-intention rule. A complete grammatical construct in the subset is tagged with the first intention information responsive to a weight associated with the first intention information exceeding an intention selection threshold.Type: ApplicationFiled: March 16, 2016Publication date: July 14, 2016Applicants: International Business Machines Corporation, Baylor College of Medicine, The Board of Regents, The University of Texas SystemInventors: Meenakshi Nagarajan, William Scott Spangler, Benjamin J. Bachman, Lawrence A. Donehower, Olivier Lichtarge, Sam J. Regenbogen, Angela D. Wilkins, Curtis R. Pickering
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Publication number: 20160162465Abstract: A new information in a language and relating to a subject matter domain is parsed into a constituent set of complete grammatical constructs. In a subset of the complete grammatical constructs, a set of linguistic styles of the language is identified according to a subset of a set of word-style associations related to the language and independent of the subject matter domain. A first weight is assigned to a first linguistic style and a second weight to a second linguistic style from the set of linguistic styles. A first intention information is mapped to the first style using a first style-intention rule, and a second intention information to the second style using a second style-intention rule. A complete grammatical construct in the subset is tagged with the first intention information responsive to a weight associated with the first intention information exceeding an intention selection threshold.Type: ApplicationFiled: December 8, 2014Publication date: June 9, 2016Applicants: International Business Machines Corporation, Baylor College of Medicine, The Board of Regents, The University of Texas SystemInventors: MEENAKSHI NAGARAJAN, William Scott Spangler, Benjamin J. Bachman, Lawrence A. Donehower, Olivier Lichtarge, Sam J. Regenbogen, Angela D. Wilkins, Curtis R. Pickering
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Publication number: 20160162788Abstract: A method, system, and computer program product for event detection using roles and relationships of entities are provided in the illustrative embodiments. A training event and a set of entities participating in the training event are identified in a training data. For a first entity in the set of entities, a first role occupied by the entity in the event is determined. A behavior attribute is assigned to the first role. A relationship of the first role with a second role corresponding to a second entity in the set of entities is determined. An event rule is constructed to detect an event corresponding to the training event in new data and comprising a plurality of roles, behavior attributes, and the relationship. The plurality of roles includes the first role and the second role, and the plurality of behavior attributes includes the behavior attribute assigned to the first role.Type: ApplicationFiled: December 8, 2014Publication date: June 9, 2016Applicants: International Business Machines Corporation, Baylor College of Medicine, The Board of Regents, The University of Texas SystemInventors: Ying Chen, Linda H. Kato, Jacques J. Labrie, Meenakshi Nagarajan, William Scott Spangler, Ioana R. Stanoi, Anbu Karani Adikesavan, Benjamin J. Bachman, Lawrence A. Donehower, Olivier Lichtarge, Sam J. Regenbogen, Maria E. Terron-Diaz, Angela D. Wilkins, Curtis R. Pickering
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Patent number: 9355089Abstract: A new information in a language and relating to a subject matter domain is parsed into a constituent set of complete grammatical constructs. In a subset of the complete grammatical constructs, a set of linguistic styles of the language is identified according to a subset of a set of word-style associations related to the language and independent of the subject matter domain. A first weight is assigned to a first linguistic style and a second weight to a second linguistic style from the set of linguistic styles. A first intention information is mapped to the first style using a first style-intention rule, and a second intention information to the second style using a second style-intention rule. A complete grammatical construct in the subset is tagged with the first intention information responsive to a weight associated with the first intention information exceeding an intention selection threshold.Type: GrantFiled: December 8, 2014Date of Patent: May 31, 2016Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventors: Meenakshi Nagarajan, William Scott Spangler, Benjamin J. Bachman, Lawrence A. Donehower, Olivier Lichtarge, Sam J. Regenbogen, Angela D. Wilkins, Curtis R. Pickering
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Publication number: 20150359840Abstract: An autophagy-inducing compound comprises an autophagy-inducing peptide comprising Beclin 1 peptides immediately N- and C-terminally flanked by moieties R1 and R2, respectively, wherein up to six of said peptide residues may be substituted, R1 and R2 do not naturally flank the Belclin 1 residues, and F270 and F274 are optionally substituted and optionally linked. The compounds may be used to induce autophagy.Type: ApplicationFiled: September 3, 2015Publication date: December 17, 2015Applicants: BAYLOR COLLEGE OF MEDICINE, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Beth C. Levine, Sanae Shoji-Kawata, Nick V. Grishin, Lisa N. Kinch, Olivier Lichtarge, Angela D. Wilkins
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Patent number: 8802633Abstract: An autophagy-inducing compound comprises an autophagy-inducing peptide comprising Beclin 1 residues 269-279 immediately N- and C-terminally flanked by moieties R1 and R2, respectively, wherein up to six of said residues may be substituted, R1 and R2 do not naturally flank the Belclin 1 residues, and F270 and F274 are optionally substituted and optionally linked. The compounds may be used to induce autophagy.Type: GrantFiled: November 8, 2013Date of Patent: August 12, 2014Assignees: Board of Regents, The University of Texas System, Baylor College of MedicineInventors: Beth C. Levine, Sanae Shoji-Kawata, Olivier Lichtarge, Angela D. Wilkins, Nick V. Grishin, Lisa N. Kinch
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Patent number: 8722628Abstract: An autophagy-inducing compound comprises an autophagy-inducing peptide comprising beclin-1 residues 269-283 and a heterologous moiety that promotes therapeutic stability or delivery of the compound. The compound may be used to induce autophagy and in assays with beclin-1 binding partners.Type: GrantFiled: November 8, 2013Date of Patent: May 13, 2014Assignee: Board of Regents, The University of Texas SystemInventors: Beth C. Levine, Sanae Shoji-Kawata, Olivier Lichtarge, Angela D. Wilkins
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Publication number: 20140066382Abstract: An autophagy-inducing compound comprises an autophagy-inducing peptide comprising beclin-1 residues 269-283 and a heterologous moiety that promotes therapeutic stability or delivery of the compound. The compound may be used to induce autophagy and in assays with beclin-1 binding partners.Type: ApplicationFiled: November 8, 2013Publication date: March 6, 2014Applicants: Baylor College of Medicine, Board of Regents, The University of Texas SystemInventors: Beth C. Levine, Sanae Shoji-Kawata, Olivier Lichtarge, Angela D. Wilkins