Patents by Inventor Angela Kalbande

Angela Kalbande has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for improving sample identification in indexed nucleic acid libraries
    Patent number: 11459610
    Abstract: The present invention is concerned with compositions and methods for improving the rate of correct sample identification in indexed nucleic acid library preparations for multiplex next generation sequencing by exonuclease treatment and optionally blocking the 3? ends of pooled indexed polynucleotides from multiple samples prior to amplification and sequencing.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: October 4, 2022
    Assignee: ILLUMINA CAMBRIDGE LIMITED
    Inventors: Michael Chesney, Vincent Peter Smith, Claire Bevis-Mott, Jonathan Mark Boutell, Angela Kalbande
  • COMPOSITIONS AND METHODS FOR IMPROVING SAMPLE IDENTIFICATION IN INDEXED NUCLEIC ACID LIBRARIES
    Publication number: 20210230689
    Abstract: The present invention is concerned with compositions and methods for improving the rate of correct sample identification in indexed nucleic acid library preparations for multiplex next generation sequencing by blocking the 3? ends of pooled indexed polynucleotides from multiple samples prior to amplification and sequencing, by exonuclease treatment and optionally blocking the 3? ends of pooled indexed polynucleotides from multiple samples prior to amplification and sequencing, by exonuclease treatment after protective adapters are ligated to target polynucleotides to degrade unincorporated adapters prior to amplification and sequencing, and/or by modifying or blocking 5? and 3? ends of pooled indexed polynucleotides from multiple samples, with an optional exonuclease treatment, prior to amplification and sequencing.
    Type: Application
    Filed: April 12, 2021
    Publication date: July 29, 2021
    Applicants: Illumina, Inc., Ilumina Cambridge Limited
    Inventors: Eric Vermaas, Mahdieh Khosroheidari, Angela Kalbande, Vincent Peter Smith, Claire Bevis-Mott, Jonathan Mark Boutell, Michael Chesney
  • Compositions and methods for improving sample identification in indexed nucleic acid libraries
    Patent number: 10995369
    Abstract: The present invention is concerned with compositions and methods for improving the rate of correct sample identification in indexed nucleic acid library preparations for multiplex next generation sequencing by exonuclease treatment after protective adapters are ligated to target polynucleotides to degrade unincorporated adapters prior to amplification and sequencing.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: May 4, 2021
    Assignees: Illumina, Inc., Illumina Cambridge Limited
    Inventors: Eric Hans Vermaas, Mahdieh Khosroheidari, Angela Kalbande
  • COMPOSITIONS AND METHODS FOR IMPROVING SAMPLE IDENTIFICATION IN INDEXED NUCLEIC ACID LIBRARIES
    Publication number: 20180305753
    Abstract: The present invention is concerned with compositions and methods for improving the rate of correct sample identification in indexed nucleic acid library preparations for multiplex next generation sequencing by exonuclease treatment and optionally blocking the 3? ends of pooled indexed polynucleotides from multiple samples prior to amplification and sequencing.
    Type: Application
    Filed: April 23, 2018
    Publication date: October 25, 2018
    Applicant: Illumina Cambridge Limited
    Inventors: Michael Chesney, Vincent Peter Smith, Claire Bevis-Mott, Jonathan Mark Boutell, Angela Kalbande
  • COMPOSITIONS AND METHODS FOR IMPROVING SAMPLE IDENTIFICATION IN INDEXED NUCLEIC ACID LIBRARIES
    Publication number: 20180305751
    Abstract: The present invention is concerned with compositions and methods for improving the rate of correct sample identification in indexed nucleic acid library preparations for multiplex next generation sequencing by exonuclease treatment after protective adapters are ligated to target polynucleotides to degrade unincorporated adapters prior to amplification and sequencing.
    Type: Application
    Filed: April 23, 2018
    Publication date: October 25, 2018
    Applicant: Illumina, Inc.
    Inventors: Eric Hans Vermaas, Mahdieh Khosroheidari, Angela Kalbande