Patents by Inventor Angela M. Devlin

Angela M. Devlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutations in human glutamate carboxypeptidase II gene impacting folate metabolism, and detection of affected individuals
    Publication number: 20040185487
    Abstract: The invention provides methods for detecting mutations in the human GCPII gene which affect the ability of an individual to hydrolyze terminal glutamates from dietary folates. Such individuals are at increased risk for conditions associated with hyperhomocyteinemia, in particular, cardiovascular disease, colon cancer, and altered cognition in the elderly, including Alzheimer's disease. In addition, pregnant women with low folate status are at increased risk of bearing children with neural tube defects and congenital heart defects. Individuals with these mutations can be screened and treated with supplementation of their diet with folic acid.
    Type: Application
    Filed: March 3, 2004
    Publication date: September 23, 2004
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Charles H. Halsted, Angela M. Devlin
  • Mutations in human glutamate carboxypeptidase II gene impacting folate metabolism, and detection of affected individuals
    Publication number: 20020009734
    Abstract: The invention provides methods for detecting mutations in the human GCPII gene which affect the ability of an individual to hydrolyze terminal glutamates from dietary folates. Such individuals are at increased risk for conditions associated with hyperhomocyteinemia, in particular, cardiovascular disease, colon cancer, and altered cognition in the elderly, including Alzheimer's disease. In addition, pregnant women with low folate status are at increased risk of bearing children with neural tube defects and congenital heart defects. Individuals with these mutations can be screened and treated with supplementation of their diet with folic acid.
    Type: Application
    Filed: March 12, 2001
    Publication date: January 24, 2002
    Inventors: Charles H. Halsted, Angela M. Devlin