Patents by Inventor Angela Ruban

Angela Ruban has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING CANCER OF THE CENTRAL NERVOUS SYSTEM
    Publication number: 20190091300
    Abstract: A method of treating a cancer of the central nervous system in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of an agent which reduces blood glutamate levels and enhances brain to blood glutamate efflux to thereby treat the cancer of the central nervous system in the subject.
    Type: Application
    Filed: November 21, 2018
    Publication date: March 28, 2019
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Vivian I. TEICHBERG, Angela RUBAN
  • Methods of treating cancer of the central nervous system
    Patent number: 10159717
    Abstract: A method of treating a cancer of the central nervous system in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of an agent which reduces blood glutamate levels and enhances brain to blood glutamate efflux to thereby treat the cancer of the central nervous system in the subject.
    Type: Grant
    Filed: April 14, 2015
    Date of Patent: December 25, 2018
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Vivian I. Teichberg, Angela Ruban
  • GLUTAMATE OXALOACETATE TRANSAMINASE 1 (GOT1), PREPARATIONS AND METHODS OF GENERATING SAME AND USES THEREOF
    Publication number: 20180071369
    Abstract: A protein preparation comprising Glutamate Oxaloacetate Transaminase 1 (GOT1) polypeptide molecules is disclosed, the GOT1 being identical in its sequence to that present in human serum. 100% of the GOT1 polypeptide molecules of the preparation have an alanine at position 1 of the GOT1 polypeptide. The GOT1 polypeptide molecules constitute at least 95% of the proteins in the preparation. Methods of generating same and uses thereof are also disclosed.
    Type: Application
    Filed: March 31, 2016
    Publication date: March 15, 2018
    Inventors: David MIRELMAN, Aharon RABINKOV, Angela RUBAN, Ghil JONA, Eli HAZUM, Vladas BUMELIS, Nerijus MAKAUSKAS, Saule SUDZIUVIENE, Elena NARMONTAITE
  • METHODS OF TREATING CANCER OF THE CENTRAL NERVOUS SYSTEM
    Publication number: 20150216949
    Abstract: A method of treating a cancer of the central nervous system in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of an agent which reduces blood glutamate levels and enhances brain to blood glutamate efflux to thereby treat the cancer of the central nervous system in the subject.
    Type: Application
    Filed: April 14, 2015
    Publication date: August 6, 2015
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Vivian I. Teichberg, Angela Ruban
  • Methods of treating cancer of the central nervous system
    Patent number: 9034319
    Abstract: A method of treating a cancer of the central nervous system in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of an agent which reduces blood glutamate levels and enhances brain to blood glutamate efflux to thereby treat the cancer of the central nervous system in the subject.
    Type: Grant
    Filed: May 26, 2008
    Date of Patent: May 19, 2015
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Vivian I. Teichberg, Angela Ruban-Matuzani
  • METHODS OF TREATING CANCER OF THE CENTRAL NERVOUS SYSTEM
    Publication number: 20110070218
    Abstract: A method of treating a cancer of the central nervous system in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of an agent which reduces blood glutamate levels and enhances brain to blood glutamate efflux to thereby treat the cancer of the central nervous system in the subject.
    Type: Application
    Filed: May 26, 2008
    Publication date: March 24, 2011
    Inventors: Vivian I. Teichberg, Angela Ruban-Matuzani