Patents by Inventor Angela Sosa-Molano

Angela Sosa-Molano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10801018
    Abstract: Disclosed are methods and compositions for reduced immunogenic proteins used in enzyme replacement therapy for lysosomal storage disorders. More specifically disclosed are genetically engineered variants of N-acetylgalactosamine-6-sulfatase (GALNS), which are less immunogenetic then wild-type GALNS, but maintain enzymatic activity, and may be used to treat Mucopolysaccharidosis IVA (Morquio A disease, MPS IVA).
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: October 13, 2020
    Assignee: Saint Louis University
    Inventors: Adriana M. Montaño-Suarez, Angela Sosa-Molano
  • Publication number: 20200032229
    Abstract: Disclosed are methods and compositions for reduced immunogenic proteins used in enzyme replacement therapy for lysosomal storage disorders. More specifically disclosed are genetically engineered variants of N-acetylgalactosamine-6-sulfatase (GALNS), which are less immunogenetic then wild-type GALNS, but maintain enzymatic activity, and may be used to treat Mucopolysaccharidosis IVA (Morquio A disease, MPS IVA).
    Type: Application
    Filed: October 11, 2019
    Publication date: January 30, 2020
    Inventors: Adriana M. Montaño-Suarez, Angela Sosa-Molano
  • Patent number: 10472615
    Abstract: Disclosed are methods and compositions for reduced immunogenic proteins used in enzyme replacement therapy for lysosomal storage disorders. More specifically disclosed are genetically engineered variants of N-acetylgalactosamine-6-sulfatase (GALNS), which are less immunogenetic then wild-type GALNS, but maintain enzymatic activity, and may be used to treat Mucopolysaccharidosis IVA (Morquio A disease, MPS IVA).
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: November 12, 2019
    Assignee: Saint Louis University
    Inventors: Adriana Montaño-Suarez, Angela Sosa-Molano
  • Publication number: 20180073000
    Abstract: Disclosed are methods and compositions for reduced immunogenic proteins used in enzyme replacement therapy for lysosomal storage disorders. More specifically disclosed are genetically engineered variants of N-acetylgalactosamine-6-sulfatase (GALNS), which are less immunogenetic then wild-type GALNS, but maintain enzymatic activity, and may be used to treat Mucopolysaccharidosis IVA (Morquio A disease, MPS IVA).
    Type: Application
    Filed: January 20, 2017
    Publication date: March 15, 2018
    Inventors: Adriana Montaño-Suarez, Angela Sosa-Molano