Patents by Inventor Angela Virone-Oddos

Angela Virone-Oddos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NATURAL KILLER (NK) CELL ENGAGERS BINDING TO NKp46 AND BCMA VARIANTS WITH FC-ENGINEERING
    Publication number: 20240034816
    Abstract: The present disclosure relates to multifunctional binding proteins comprising a first and a second antigen binding domains (ABDs) and all or part of an immunoglobulin Fc region or variant thereof, wherein the first ABD binds specifically to human BCMA and the second ABD binds specifically to human NKp46 and wherein all or part of the immunoglobulin Fc region or variant thereof bind to a human Fc-? receptor. The disclosure also relates to methods for making said binding proteins, compositions thereof, and their uses, including the treatment or prevention of proliferative disorders, including multiple myeloma (MM).
    Type: Application
    Filed: September 19, 2023
    Publication date: February 1, 2024
    Inventors: Nicolas GOURDIN, Laurent GAUTHIER, Alexandre TANG, Marielle CHIRON, Angela VIRONE-ODDOS, Alessandro MASIERO, Jochen BENINGA, Ingo FOCKEN, Sambasiva RAO, Yanfeng ZHOU, Leila SEVIGNY
  • MULTIFUNCTIONAL NATURAL KILLER (NK) CELL ENGAGERS BINDING TO NKp46 AND CD123
    Publication number: 20230416383
    Abstract: The present disclosure relates to multifunctional binding proteins comprising a first and a second antigen binding domains (ABDs) and all or part of an immunoglobulin Fc region or variant thereof, wherein the first ABD binds specifically to human CD123 and the second ABD binds specifically to human NKp46 and wherein all or part of the immunoglobulin Fc region or variant thereof to a human Fc-? receptor. The disclosure also relates to methods for making said binding proteins, compositions thereof, and their uses, including the treatment or prevention of proliferative disorders, including Acute Myeloid Leukemia (AML) and myelodysplastic syndromes (MDS).
    Type: Application
    Filed: April 28, 2023
    Publication date: December 28, 2023
    Inventors: Marielle CHIRON, Angela Virone-Oddos, Laurent Gauthier
  • ANTI-CD38 ANTIBODIES AND FORMULATIONS
    Publication number: 20230416395
    Abstract: Provided herein are antibodies that specifically bind human CD38, formulations and unit dosage forms comprising the antibodies, methods of preparing the antibodies and methods of using the antibodies.
    Type: Application
    Filed: April 14, 2023
    Publication date: December 28, 2023
    Inventors: Marielle CHIRON BLONDEL, Cendrine LEMOINE, Angela VIRONE-ODDOS, Béatrice CAMERON, Jacques DUMAS, Alain FOURNIER, Jonathan KINGSBURY, Brian MURRAY, Nathan OSTBERG, Sanket PATKE, Zichuan ZHANG
  • Multifunctional natural killer (NK) cell engagers binding to NKp46 and CD123
    Patent number: 11692039
    Abstract: The present disclosure relates to multifunctional binding proteins comprising a first and a second antigen binding domains (ABDs) and all or part of an immunoglobulin Fc region or variant thereof, wherein the first ABD binds specifically to human CD123 and the second ABD binds specifically to human NKp46 and wherein all or part of the immunoglobulin Fc region or variant thereof to a human Fc-? receptor. The disclosure also relates to methods for making said binding proteins, compositions thereof, and their uses, including the treatment or prevention of proliferative disorders, including Acute Myeloid Leukemia (AML) and myelodysplastic syndromes (MDS).
    Type: Grant
    Filed: December 30, 2021
    Date of Patent: July 4, 2023
    Inventors: Marielle Chiron, Angela Virone-Oddos, Laurent Gauthier
  • Anti-CD38 antibodies and formulations
    Patent number: 11655302
    Abstract: Provided herein are antibodies that specifically bind human CD38, formulations and unit dosage forms comprising the antibodies, methods of preparing the antibodies and methods of using the antibodies.
    Type: Grant
    Filed: June 9, 2020
    Date of Patent: May 23, 2023
    Assignee: SANOFI
    Inventors: Marielle Chiron Blondel, Cendrine Lemoine, Angela Virone-Oddos, Béatrice Cameron, Jacques Dumas, Alain Fournier, Jonathan Kingsbury, Brian Murray, Nathan Ostberg, Sanket Patke, Zichuan Zhang
  • MULTIFUNCTIONAL NATURAL KILLER (NK) CELL ENGAGERS BINDING TO NKp46 AND CD123
    Publication number: 20220213202
    Abstract: The present disclosure relates to multifunctional binding proteins comprising a first and a second antigen binding domains (ABDs) and all or part of an immunoglobulin Fc region or variant thereof, wherein the first ABD binds specifically to human CD123 and the second ABD binds specifically to human NKp46 and wherein all or part of the immunoglobulin Fc region or variant thereof to a human Fc-? receptor. The disclosure also relates to methods for making said binding proteins, compositions thereof, and their uses, including the treatment or prevention of proliferative disorders, including Acute Myeloid Leukemia (AML) and myelodysplastic syndromes (MDS).
    Type: Application
    Filed: December 30, 2021
    Publication date: July 7, 2022
    Inventors: Céline AMARA, Céline NICOLAZZI, Marielle CHIRON, Francis DUFFIEUX, Jochen BENINGA, Angela VIRONE-ODDOS, Laurent GAUTHIER, Ariane THIELENS, Benjamin ROSSI
  • ANTI-CD38 ANTIBODIES AND FORMULATIONS
    Publication number: 20200399391
    Abstract: Provided herein are antibodies that specifically bind human CD38, formulations and unit dosage forms comprising the antibodies, methods of preparing the antibodies and methods of using the antibodies.
    Type: Application
    Filed: June 9, 2020
    Publication date: December 24, 2020
    Inventors: Marielle CHIRON BLONDEL, Cendrine LEMOINE, Angela VIRONE-ODDOS, Béatrice CAMERON, Jacques DUMAS, Alain FOURNIER, Jonathan KINGSBURY, Brian MURRAY, Nathan OSTBERG, Sanket PATKE, Zichuan ZHANG
  • ANTI-TUMORAL COMPOSITION COMPRISING A PI3KBETA INHIBITOR AND A RAF INHIBITOR, TO OVERCOME CANCER CELLS RESISTANCE
    Publication number: 20160030438
    Abstract: The present invention concerns a combination of a PI3K? inhibitor with a RAF inhibitor for its use for the treatment of a patient resistant to at least one RAF inhibitor, a kit comprising the same, its pharmaceutical uses thereof and a method of monitoring the efficiency of said combination when administered to a patient.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Inventors: Hélène BONNEVAUX, Carlos GARCIA-ECHEVERRIA, Angela VIRONE-ODDOS
  • ANTI-TUMORAL COMPOSITION COMPRISING A PI3KBETA-SELECTIVE INHIBITOR AND A PI3KALPHA-SELECTIVE INHIBITOR
    Publication number: 20160030440
    Abstract: The present invention concerns a combination of a PI3K? selective inhibitor with a PI3K? selective inhibitor for use in the treatment of cancer.
    Type: Application
    Filed: April 3, 2014
    Publication date: February 4, 2016
    Inventors: Héléne BONNEVAUX, Carlos GARCIA-ECHEVERRIA, Angela VIRONE-ODDOS
  • COMPOSITIONS AND METHODS FOR TREATING CANCER USING PI3KB INHIBITOR AND MAPK PATHWAY INHIBITOR, INCLUDING MEK AND RAF INHIBITORS
    Publication number: 20140275078
    Abstract: The present invention relates to compositions comprising at least one MAPK pathway inhibitor including MEK and RAF inhibitors and at least one PI3K? inhibitor, and also to uses thereof for the treatment of cancer.
    Type: Application
    Filed: September 14, 2012
    Publication date: September 18, 2014
    Applicant: SANOFI
    Inventors: Carlos Garcia-Echeverria, Loïc Vincent, Angela Virone-Oddos