Patents by Inventor Angela Zampella

Angela Zampella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • QUINOLINE COMPOUNDS AS SELECTIVE AND/OR DUAL MODULATORS OF BILE ACID RECEPTORS AND LEUKOTRIENE CYSTEINYL RECEPTORS
    Publication number: 20230357159
    Abstract: The present invention relates to compounds of formula (I), their pharmaceutical compositions and uses, in particular for the treatment and/or prevention of diseases mediated by bile acid receptors, FXR and GPBAR1, and cysteinyl leukotriene receptors (CysLTR).
    Type: Application
    Filed: August 4, 2021
    Publication date: November 9, 2023
    Inventors: Angela Zampella, Stefano Fiorucci
  • 6-SUBSTITUTED, 22-CYANO HYODEOXYCHOLANIC ANALOGUES AND USES THEREOF
    Publication number: 20230066156
    Abstract: The present invention relates to compounds of formula (I), to pharmaceutical compositions thereof and to their uses, in particular in the treatment and/or prevention of GPBAR1 mediated diseases.
    Type: Application
    Filed: December 9, 2020
    Publication date: March 2, 2023
    Inventors: Angela Zampella, Stefano Fiorucci
  • Isoxazole as FXR receptor agonists
    Patent number: 11332450
    Abstract: The present invention related to compounds of formula (I), to pharmaceutical compositions thereof and to their uses, in particular in the treatment and/or prevention of FXR mediated diseases.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: May 17, 2022
    Assignee: Bar Pharmaceuticals Societa' A Responsabilita' Limitata
    Inventors: Angela Zampella, Stefano Fiorucci
  • Cholane derivatives for use in the treatment and/or prevention of FXR and TGR5/GPBAR1 mediated diseases
    Patent number: 11117926
    Abstract: The present invention relates to compounds having cholane scaffolds of formula (I), said compounds for use in the treatment and/or prevention of FXR and TGR5/GPBARI mediated diseases.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: September 14, 2021
    Assignee: BAR PHARMACEUTICALS S.R.L.
    Inventors: Angela Zampella, Stefano Fiorucci
  • Isoxazole as FXR Receptor Agonists
    Publication number: 20210269409
    Abstract: The present invention related to compounds of formula (I), to pharmaceutical compositions thereof and to their uses, in particular in the treatment and/or prevention of FXR mediated diseases.
    Type: Application
    Filed: July 17, 2019
    Publication date: September 2, 2021
    Inventors: Angela Zampella, Stefano Fiorucci
  • CHOLANE DERIVATIVES FOR USE IN THE TREATMENT AND/OR PREVENTION OF FXR AND TGR5/GPBAR1 MEDIATED DISEASES
    Publication number: 20190352328
    Abstract: The present invention relates to compounds having cholane scaffolds of formula (I), said compounds for use in the treatment and/or prevention of FXR and TGR5/GPBAR1 mediated diseases.
    Type: Application
    Filed: August 1, 2019
    Publication date: November 21, 2019
    Inventors: Angela Zampella, Stefano Fiorucci
  • Cholane derivatives for use in the treatment and/or prevention of FXR and TGR5/GPBAR1 mediated diseases
    Patent number: 10407462
    Abstract: The present invention relates to compounds having cholane scaffolds of formula (I), said compounds for use in the treatment and/or prevention of FXR and TGR5/GPBAR1 mediated diseases.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: September 10, 2019
    Assignee: BAR PHARMACEUTICALS S.R.L.
    Inventors: Angela Zampella, Stefano Fiorucci
  • CHOLANE DERIVATIVES FOR USE IN THE TREATMENT AND/OR PREVENTION OF FXR AND TGR5/GPBAR1 MEDIATED DISEASES
    Publication number: 20170190731
    Abstract: The present invention relates to compounds having cholane scaffolds of formula (I), said compounds for use in the treatment and/or prevention of FXR and TGR5/GPBAR1 mediated diseases.
    Type: Application
    Filed: May 28, 2015
    Publication date: July 6, 2017
    Applicant: BAR PHARMACEUTICALS S.R.L.
    Inventors: Angela Zampella, Stefano Fiorucci