Patents by Inventor Angelica Moksa

Angelica Moksa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR SELECTING POLYNUCLEOTIDES ENCODING ANTIGEN-SPECIFIC IMMUNOGLOBULIN SUBUNIT
    Publication number: 20170306318
    Abstract: The present invention relates to a high efficiency method of expressing immunoglobulin molecules in eukaryotic cells. The invention is further drawn to a method of producing immunoglobulin heavy and light chain libraries, particularly using the trimolecular recombination method, for expression in eukaryotic cells. The invention further provides methods of selecting and screening for antigen-specific immunoglobulin molecules, and antigen-specific fragments thereof. The invention also provides kits for producing, screening and selecting antigen-specific immunoglobulin molecules. Finally, the invention provides immunoglobulin molecules, and antigen-specific fragments thereof, produced by the methods provided herein.
    Type: Application
    Filed: June 12, 2017
    Publication date: October 26, 2017
    Inventors: Ernest S. Smith, Tracy Pandina, Leslie A. Croy, Mark Paris, Maurice Zauderer, Angelica Moksa, Renee Kirk
  • Fusion proteins to facilitate selection of cells infected with specific immunoglobulin gene recombinant vaccinia virus
    Patent number: 9708601
    Abstract: The present invention relates to a high efficiency method of expressing immunoglobulin molecules in eukaryotic cells. The invention is further drawn to a method of producing immunoglobulin heavy and light chain libraries, particularly using the trimolecular recombination method, for expression in eukaryotic cells. The invention further provides methods of selecting and screening for antigen-specific immunoglobulin molecules, and antigen-specific fragments thereof. The invention also provides kits for producing, screening and selecting antigen-specific immunoglobulin molecules. Finally, the invention provides immunoglobulin molecules, and antigen-specific fragments thereof, produced by the methods provided herein.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: July 18, 2017
    Assignee: VACCINEX, INC.
    Inventors: Ernest S. Smith, Tracy Pandina, Leslie A. Croy, Mark Paris, Maurice Zauderer, Angelica Moksa, Renee Kirk
  • Method for selecting polynucleotides encoding antigen-specific immunoglobulin subunits
    Patent number: 9701958
    Abstract: The present invention relates to a high efficiency method of expressing immunoglobulin molecules in eukaryotic cells. The invention is further drawn to a method of producing immunoglobulin heavy and light chain libraries, particularly using the trimolecular recombination method, for expression in eukaryotic cells. The invention further provides methods of selecting and screening for antigen-specific immunoglobulin molecules, and antigen-specific fragments thereof. The invention also provides kits for producing, screening and selecting antigen-specific immunoglobulin molecules. Finally, the invention provides immunoglobulin molecules, and antigen-specific fragments thereof, produced by the methods provided herein.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: July 11, 2017
    Assignee: VACCINEX, INC.
    Inventors: Ernest S. Smith, Tracy Pandina, Leslie A. Croy, Mark Paris, Maurice Zauderer, Angelica Moksa, Renee Kirk
  • Method for Selecting Polynucleotides Encoding Antigen-Specific Immunoglobulin Subunits
    Publication number: 20160152971
    Abstract: The present invention relates to a high efficiency method of expressing immunoglobulin molecules in eukaryotic cells. The invention is further drawn to a method of producing immunoglobulin heavy and light chain libraries, particularly using the trimolecular recombination method, for expression in eukaryotic cells. The invention further provides methods of selecting and screening for antigen-specific immunoglobulin molecules, and antigen-specific fragments thereof. The invention also provides kits for producing, screening and selecting antigen-specific immunoglobulin molecules. Finally, the invention provides immunoglobulin molecules, and antigen-specific fragments thereof, produced by the methods provided herein.
    Type: Application
    Filed: December 21, 2015
    Publication date: June 2, 2016
    Inventors: Ernest S. Smith, Tracy Pandina, Leslie A. Croy, Mark Paris, Maurice Zauderer, Angelica Moksa, Renee Kirk
  • Fusion Proteins to Facilitate Selection of Cells Infected with Specific Immunoglobulin Gene Recombinant Vaccinia Virus
    Publication number: 20130288927
    Abstract: The present invention relates to a high efficiency method of expressing immunoglobulin molecules in eukaryotic cells. The invention is further drawn to a method of producing immunoglobulin heavy and light chain libraries, particularly using the trimolecular recombination method, for expression in eukaryotic cells. The invention further provides methods of selecting and screening for antigen-specific immunoglobulin molecules, and antigen-specific fragments thereof. The invention also provides kits for producing, screening and selecting antigen-specific immunoglobulin molecules. Finally, the invention provides immunoglobulin molecules, and antigen-specific fragments thereof, produced by the methods provided herein.
    Type: Application
    Filed: March 15, 2013
    Publication date: October 31, 2013
    Inventors: Ernest S. SMITH, Tracy Pandina, Leslie A. Croy, Mark Paris, Maurice Zauderer, Angelica Moksa, Renee Kirk