Patents by Inventor Angelika Bottger

Angelika Bottger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of the interaction between P53 and MDM2
    Patent number: 7083983
    Abstract: The present invention relates to compounds capable of binding to the oncogene protein MDM2, processes for the preparation of such compounds, pharmaceutical preparations comprising such compounds, and uses of said compounds, e.g. in the therapeutic (including prophylactic) treatment of an animal or especially of the human body. The present further relates to methods of and compounds for inhibiting the growth of tumor cells which comprise the wild type p53 suppressor by interfering with the interaction between human p53 and human MDM2.
    Type: Grant
    Filed: July 4, 1997
    Date of Patent: August 1, 2006
    Assignee: Cancer Research Campaign Technology Limited
    Inventors: David Philip Lane, Volker Böttger, Angelika Böttger, Steven Michael Picksley, Heinz-Kurt Hochkeppel, Carlos Garcia-Echeverria, Patrick Chène, Pascal Furet
  • Inhibitors of the Interaction between p53 and MDM2
    Publication number: 20050137137
    Abstract: The present invention relates to compounds capable of binding to the oncogene protein MDM2, processes for the preparation of such compounds, pharmaceutical preparations comprising such compounds, and uses of said compounds, e.g. in the therapeutic (including prophylactic) treatment of an animal or especially of the human body. The present further relates to methods of and compounds for inhibiting the growth of tumor cells which comprise the wild type p53 suppressor by interfering with the interaction between human p53 and human MDM2.
    Type: Application
    Filed: August 25, 2004
    Publication date: June 23, 2005
    Inventors: David Lane, Volker Bottger, Angelika Bottger, Steven Picksley, Heinz-Kurt Hochkeppel, Carlos Garcia-Echeverria, Patrick Chene, Pascal Furet
  • INHIBITORS OF THE INTERACTION BETWEEN P53 AND MDM2
    Publication number: 20010018511
    Abstract: The present invention relates to compounds capable of binding to the oncogene protein MDM2, processes for the preparation of such compounds, pharmaceutical preparations comprising such compounsa, and uses of said compounds, e.g. in the therapeutic (including prophylactic) treatment of an animal or especially of the human body. The present further relates to methods of and compounds for inhibiting the growth of tumor cells which comprise the wild typr p53 suppressor by interfering with the interaction between human p53 and human MDM2.
    Type: Application
    Filed: March 26, 1999
    Publication date: August 30, 2001
    Inventors: DAVID LANE, VOLKER BOTTGER, ANGELIKA BOTTGER, STEVEN MICHAEL PICKSLEY, HEINZ-KURT HOCHKEPPEL, CARLOS GARCIA-ECHEVERRIA, PATRICK CHENE, PASCAL FURET
  • Agents for inducing apoptosis and applications of said agents in therapy
    Patent number: 5968824
    Abstract: Agents which modulate pathways of apoptotic induction or repression in which products of opioid peptide precursors genes participate, useful as inducers of apoptosis in cells and in tumor cells in particular, are disclosed. Methods of treatment employing such agents and pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: April 28, 1997
    Date of Patent: October 19, 1999
    Inventors: Barbara Ann Spruce, Alan Prescott, Angelika Bottger, Deborah Ann Dewar