Patents by Inventor Angelina M. Thayer

Angelina M. Thayer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inducible nitric oxide synthase dimerization inhibitors
    Patent number: 7825256
    Abstract: The present invention relates to compounds and methods useful as inhibitors of nitric oxide synthase. Certain compounds of the subject invention have the following structural formula: wherein T, X, and Y are independently selected from the group consisting of CR4, N, NR4, S, and O; U is selected from the group consisting of CR10 and N; V is selected from the group consisting of CR4 and N; W and W? are independently selected from the group consisting of CH2, CR7R8, NR9, O, N(O), S(O)q and C(O); n, m and p are independently an integer from 0 to 5; q is 0, 1, or 2; and other substituents are as defined herein. Other compounds of the subject invention have structural formulas as defined herein. Also disclosed herein are pharmaceutical compositions comprising the compounds of the subject invention.
    Type: Grant
    Filed: November 28, 2005
    Date of Patent: November 2, 2010
    Assignee: Kalypsys, Inc.
    Inventors: Timothy C. Gahman, Hengyuan Lang, Mark R. Herbert, Angelina M. Thayer, Christian A. Hassig, Stewart A. Noble, Russell D. Cousins, Hui Zhuang, Christopher R. Santos, Xiaohong Chen