Patents by Inventor Angeline Douvas

Angeline Douvas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Viral chimeras comprised of CAEV and HIV-1 genetic elements
    Patent number: 6602505
    Abstract: The invention provides a polynucleotide comprising portions of the genomes of caprine arthritis-encephalitis virus and HIV-1, resulting in a chimeric retrovirus referred to as a “CHIV. ” The invention also provides a vaccine comprising a CHIV immunogen and a pharmaceutically acceptable carrier. A method of stimulating an immune response in an individual-against human immunodeficiency virus-1 infection by administering a therapeutically effective amount of a CHIV immunogen is also provided. The invention further provides a method of stimulating an immune response in vitro by contacting a lymphocyte with a therapeutically effective amount of a CHIV immunogen.
    Type: Grant
    Filed: April 29, 1999
    Date of Patent: August 5, 2003
    Assignee: University of Southern California
    Inventors: Angeline Douvas, Tyler B. Parr
  • VIRAL CHIMERAS COMPRISED OF CAEV AND HIV-1 GENETIC ELEMENTS
    Publication number: 20010039669
    Abstract: The present invention provides a polynucleotide comprising portions of the genomes of caprine arthritis-encephalitis virus and HIV-1, resulting in a chimeric retrovirus referred to as a “CHIV.” The invention also provides a vaccine comprising a CHIV immunogen and a pharmaceutically acceptable carrier. A method of stimulating an immune response in an individual against human immunodeficiency virus-1 infection by administering a therapeutically effective amount of a CHIV immunogen is also provided. The invention further provides a method of stimulating an immune response in vitro by contacting a lymphocyte with a therapeutically effective amount of a CHIV immunogen.
    Type: Application
    Filed: April 29, 1999
    Publication date: November 8, 2001
    Inventors: ANGELINE DOUVAS, GLENN EHRESMANN
  • Method of stimulating an immune response to caprine arthritis-encephalitis virus (CAEV) in humans through the administration of CAEV immunogens
    Patent number: 6033672
    Abstract: The present invention provides a vaccine comprising a caprine arthritis-encephalitis virus (CAEV) immunogen and a pharmaceutically acceptable carrier. The invention also provides a method of stimulating an immune response in an individual against human immunodeficiency virus-1 infection or against CAEV infection by administering a therapeutically effective amount of a CAEV immunogen to the individual. The invention further provides a method of stimulating an immune response in vitro by contacting a lymphocyte with a therapeutically effective amount of a CAEV immunogen.
    Type: Grant
    Filed: March 15, 1996
    Date of Patent: March 7, 2000
    Assignee: University of Southern California
    Inventors: Angeline Douvas, Glenn Ehresmann
  • Method of diagnosing caprine arthritis-encephalitis virus infection
    Patent number: 5770357
    Abstract: The present invention provides a method of diagnosing caprine arthritis-encephalitis virus infection (CAEV) in a human sample suspected of being infected with CAEV.
    Type: Grant
    Filed: March 15, 1996
    Date of Patent: June 23, 1998
    Inventors: Angeline Douvas, Glenn Ehresmann
  • Methods of treating HIV infection using antibodies to the U2 small nuclear ribonuclear protein
    Patent number: 5707626
    Abstract: Therapeutic strategies for the treatment of immunoinfective cluster virus infections in humans involving the use of antibodies or fragments thereof which are characteristic of autoantibodies produced by patients affected with systemic rheumatic disorders and cross-react with epitopes on an immunoinfective cluster virus. Additional therapeutic strategies include the use U1 RNA or fragments thereof to treat said viral infections.
    Type: Grant
    Filed: August 28, 1996
    Date of Patent: January 13, 1998
    Assignee: University of Southern California
    Inventors: Angeline Douvas, Yoshi Takehana, Glenn Ehresmann