Abstract: A gastrointestinal simulator system includes a thermoregulated bath, two glass beakers situated within the thermoregulated water bath, and a pump. The beakers simulate the stomach and intestines and are coupled together using a tube. A sieve, positioned within the “stomach,” has a plurality of 2 mm holes on its surface to mimic in vivo conditions, where only particles smaller than 2 mm in diameter are transferred to the “intestines.” These collected particles move from “stomach” (specifically, from the sieve) to the “intestines” through the tube coupling the beakers. Cameras may be located inside the water bath for monitoring/recording of the digestion. Alerts, such as voice alerts, may be generated to notify users of any important information and instructions. After digestion, reports of the digestion are automatically generated and stored in a data repository. One or more users are notified that the reports are available for access.

Abstract: An in vitro dynamic mouth model includes an upper jaw that includes a plurality of protuberances simulating human teeth, a lower jaw that is coupled with a rounded silicone pad simulating human tongue, and a mouth wall that encapsulates food sample(s) subjected to in vitro mastication such that the food sample remains within the mouth model. The mouth wall contains at least one hole that allows injection of simulated saliva fluid. As simulated chewing takes place, the injected fluid directly interacts with the food sample.

Abstract: A gastrointestinal simulator system includes a thermoregulated bath, two glass beakers situated within the thermoregulated water bath, and a pump. The beakers simulate the stomach and intestines and are coupled together using a tube. A sieve, positioned within the “stomach,” has a plurality of 2 mm holes on its surface to mimic in vivo conditions, where only particles smaller than 2 mm in diameter are transferred to the “intestines.” These collected particles move from “stomach” (specifically, from the sieve) to the “intestines” through the tube coupling the beakers. Cameras may be located inside the water bath for monitoring/recording of the digestion. Alerts, such as voice alerts, may be generated to notify users of any important information and instructions. After digestion, reports of the digestion are automatically generated and stored in a data repository. One or more users are notified that the reports are available for access.

Abstract: A gastrointestinal simulator system includes a thermoregulated bath, two glass beakers situated within the thermoregulated water bath, and a pump. The beakers simulate the stomach and intestines and are coupled together using a tube. A sieve, positioned within the “stomach,” has a plurality of 2 mm holes on its surface to mimic in vivo conditions, where only particles smaller than 2 mm in diameter are transferred to the “intestines.” These collected particles move from “stomach” (specifically, from the sieve) to the “intestines” through the tube coupling the beakers. Cameras may be located inside the water bath for monitoring/recording of the digestion. Alerts, such as voice alerts, may be generated to notify users of any important information and instructions. After digestion, reports of the digestion are automatically generated and stored in a data repository. One or more users are notified that the reports are available for access.