Patents by Inventor Angelique A.C. Lemckert

Angelique A.C. Lemckert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Serotype of adenovirus and uses thereof
    Publication number: 20100034774
    Abstract: Adenovirus serotypes differ in their natural tropism. The adenovirus serotypes 2, 4, 5 and 7 all have a natural affiliation towards lung epithelia and other respiratory tissues. In contrast, serotypes 40 and 41 have a natural affiliation towards the gastrointestinal tract. The serotypes described differ in at least capsid proteins (penton-base, hexon), proteins responsible for cell binding (fiber protein), and proteins involved in adenovirus replication. This difference in tropism and capsid protein among serotypes has led to the many research efforts aimed at redirecting the adenovirus tropism by modification of the capsid proteins.
    Type: Application
    Filed: July 23, 2009
    Publication date: February 11, 2010
    Applicant: Crucell Holland B.V.
    Inventors: Ronald Vogels, Angelique A.C. Lemckert, Menzo J.E. Havenga