Patents by Inventor Angelo FREI

Angelo FREI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multinuclear complexes and their preparation
    Patent number: 11690923
    Abstract: Multinuclear complexes and methods for preparing them are provided. The discrete multinuclear complexes include a one or more transition metals and a radioisotope having the same coordination geometry as the transition metal. A bridging ligand is coordinated to the transition metal and the radioisotope to link the transition metal and the radioisotope and pendent ligands are coordinated to each of the transition metal and the radioisotope to stabilise the complex. The multinuclear complexes may include a radioisotope or radioelement that can be detected by medical equipment and may find use in therapy and/or the diagnosis of disease in patients.
    Type: Grant
    Filed: July 19, 2021
    Date of Patent: July 4, 2023
    Assignees: UNIVERSITY OF THE FREE STATE, UNIVERSITAT ZURICH
    Inventors: Andreas Roodt, Roger Ariel Alberto, Angelo Frei, Petrus Pennie Mokolokolo, Robin Kim Bollinger, Alice Brink, Dumisani Vincent Kama
  • Ruthenium (II) Complexes and Their Use as AntiCancer Agents
    Publication number: 20220242894
    Abstract: The present invention relates to a compound of the following formula (I): (I) or a pharmaceutically acceptable salt and/or solvate thereof, notably for use as a drug, in particular in the treatment of cancer. The present invention also relates to a pharmaceutical composition comprising such a compound and to a method for the preparation of such a compound.
    Type: Application
    Filed: May 27, 2020
    Publication date: August 4, 2022
    Inventors: Gilles Albert Gasser, Angelo Frei, Riccardo Rubbiani, Anna Notaro
  • MULTINUCLEAR COMPLEXES AND THEIR PREPARATION
    Publication number: 20210393813
    Abstract: Multinuclear complexes and methods for preparing them are provided. The discrete multinuclear complexes include a one or more transition metals and a radioisotope having the same coordination geometry as the transition metal. A bridging ligand is coordinated to the transition metal and the radioisotope to link the transition metal and the radioisotope and pendent ligands are coordinated to each of the transition metal and the radioisotope to stabilise the complex. The multinuclear complexes may include a radioisotope or radioelement that can be detected by medical equipment and may find use in therapy and/or the diagnosis of disease in patients.
    Type: Application
    Filed: July 19, 2021
    Publication date: December 23, 2021
    Applicants: UNIVERSITY OF THE FREE STATE, UNIVERSITÄT ZÜRICH
    Inventors: Andreas ROODT, Roger Ariel ALBERTO, Angelo FREI, Petrus Pennie MOKOLOKOLO, Robin Kim BOLLINGER, Alice BRINK, Dumisani Vincent KAMA
  • MULTINUCLEAR COMPLEXES AND THEIR PREPARATION
    Publication number: 20200330623
    Abstract: Multinuclear complexes and methods for preparing them are provided. The discrete multinuclear complexes include a one or more transition metals and a radioisotope having the same coordination geometry as the transition metal. A bridging ligand is coordinated to the transition metal and the radioisotope to link the transition metal and the radioisotope and pendent ligands are coordinated to each of the transition metal and the radioisotope to stabilise the complex. The multinuclear complexes may include a radioisotope or radioelement that can be detected by medical equipment and may find use in therapy and/or the diagnosis of disease in patients.
    Type: Application
    Filed: December 21, 2018
    Publication date: October 22, 2020
    Applicants: UNIVERSITY OF THE FREE STATE, UNIVERSITÄT ZÜRICH
    Inventors: Andreas ROODT, Roger Ariel ALBERTO, Angelo FREI, Petrus Pennie MOKOLOKOLO, Robin Kim BOLLINGER, Alice BRINK, Dumisani Vincent KAMA