Patents by Inventor Angelo Mao

Angelo Mao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recapitulating the hematopoietic niche to reconstitute immunity
    Patent number: 11752238
    Abstract: Disclosed are compositions and related methods of recapitulating bone marrow stroma using scaffold materials (e.g., a porous alginate hydrogel scaffold) containing one or more cellular differentiation factors, and one or more growth factors. Such methods and compositions promote the formation of an ectopic nodule or site that can improve transplanted cell engraftment and selectively drive the development of lymphocytes and the reconstitution of the adaptive immunity after hematopoietic stem cell transplant.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: September 12, 2023
    Assignees: President and Fellows of Harvard College, The General Hospital Corporation
    Inventors: Nisarg J. Shah, Ting-Yu Shih, Angelo Mao, David J. Mooney, David T. Scadden
  • RECAPITULATING THE HEMATOPOIETIC NICHE TO RECONSTITUTE IMMUNITY
    Publication number: 20190060525
    Abstract: Disclosed are compositions and related methods of recapitulating bone marrow stroma using scaffold materials (e.g., a porous alginate hydrogel scaffold) containing one or more cellular differentiation factors, and one or more growth factors. Such methods and compositions promote the formation of an ectopic nodule or site that can improve transplanted cell engraftment and selectively drive the development of lymphocytes and the reconstitution of the adaptive immunity after hematopoietic stem cell transplant.
    Type: Application
    Filed: February 6, 2017
    Publication date: February 28, 2019
    Inventors: Nisarg J. Shah, Ting-Yu Shih, Angelo Mao, David J. Mooney, David T. Scadden