Patents by Inventor Angelo Pugliese

Angelo Pugliese has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250092023
    Abstract: The present disclosure provides piperazine substituted fused azadecalin compounds of Formula J, I, Ia, Ib, Ib-1, Ib-2, Ic and Id for use in pharmaceutical formulations, and for modulating glucocorticoid receptors.
    Type: Application
    Filed: August 8, 2024
    Publication date: March 20, 2025
    Inventors: Mark Mills, Andrew William Phillips, Bohdan Waszkowycz, Hazel Joan Hunt, Angus Morrison, Angelo Pugliese, Jonathan Gillespie, Euan Fordyce
  • Patent number: 12098144
    Abstract: Provided are piperazine substituted fused azadecalin compounds of Formula J, I, Ia, Ib, Ib-1, Ib-2, Ic and Id for use in pharmaceutical formulations, and for modulating glucocorticoid receptors.
    Type: Grant
    Filed: December 20, 2022
    Date of Patent: September 24, 2024
    Assignee: Corcept Therapeutics Incorporated
    Inventors: Mark Mills, Andrew William Phillips, Bohdan Waszkowycz, Hazel Joan Hunt, Angus Morrison, Angelo Pugliese, Jonathan Gillespie, Euan Fordyce
  • Publication number: 20230192666
    Abstract: The present disclosure provides piperazine substituted fused azadecalin compounds of Formula J, I, Ia, Ib, Ib-1, Ib-2, Ic and Id for use in pharmaceutical formulations, and for modulating glucocorticoid receptors.
    Type: Application
    Filed: December 20, 2022
    Publication date: June 22, 2023
    Inventors: Mark Mills, Andrew William Phillips, Bohdan Waszkowycz, Hazel Joan Hunt, Angus Morrison, Angelo Pugliese, Jonathan Gillespie, Euan Fordyce
  • Patent number: 11447505
    Abstract: The present application relates to a compound of Formula I, or a salt, hydrate or solvate thereof, as defined herein. The present compounds are found to have pharmacological effects, particularly at MRCK. Further provided are pharmaceutical compositions comprising said compounds. The present invention also relates to the use of these compounds as therapeutic agents, in particular, for the treatment and/or prevention of proliferative diseases, such as cancer.
    Type: Grant
    Filed: August 17, 2018
    Date of Patent: September 20, 2022
    Assignee: Cancer Research Technology Limited
    Inventors: Angelo Pugliese, Stuart Francis, Duncan McArthur, Mairi Sime, Justin Bower, Simone Belshaw
  • Publication number: 20070018365
    Abstract: The present invention provides a method for manufacturing fountainheads, as well as fountainheads made by the process that include non-circular and non-oval-shaped (e.g., square, triangular and rectangular) holes. The method of manufacturing involves a number of steps including the following: creating a design for the fountainhead; constructing at least two mold cavities based on the design; using the two cavities to form fountainhead pieces; and, combining the fountainhead pieces.
    Type: Application
    Filed: July 6, 2005
    Publication date: January 25, 2007
    Inventor: Angelo Pugliese
  • Publication number: 20060112482
    Abstract: A gasket for a spa shell includes a body formed of an at least partially translucent material. The gasket includes a top ring configured to abut a top surface of the spa shell and a bottom ring configured to abut a bottom surface of the spa shell. In one embodiment, the gasket includes an indentation configured to receive light from a light source for transmission through the body. The gasket may be formed with an elastomer.
    Type: Application
    Filed: December 1, 2004
    Publication date: June 1, 2006
    Inventors: Victor Walker, Garth Weber, Angelo Pugliese, Timothy Pflueger
  • Publication number: 20050067339
    Abstract: Systems and methods to filter water. A filtration device for a floodable compartment having a water inlet and a water outlet can include a removable filter for being positioned at or near the water outlet of the compartment, a strainer having a first end and a second end, wherein the first end is configured to at least partially surround the filter near the water outlet, and wherein the second end is configured to contact the compartment at least partially around the filter at a point in the compartment between the water inlet and the water outlet. The filtration device can be implemented as a water filtration system for a pool or spa, where the water inlet can be from the pool or spa, and the water outlet can be to a pump.
    Type: Application
    Filed: September 30, 2003
    Publication date: March 31, 2005
    Inventors: James McClure, Angelo Pugliese