Abstract: Disclosed herein are isolated rubella viral vector constructs that include a rubella non-structural protein open reading frame (ORF) with an in-frame deletion, a rubella structural protein ORF, and a heterologous antigenic insert. In one example, the in-frame deletion within the rubella non-structural protein ORF is an in-frame deletion between two NotI restriction enzyme sites. In some examples, the heterologous antigenic insert is positioned within the rubella non-structural protein ORF. In other examples, the heterologous antigenic insert is positioned within the rubella structural protein ORF. Exemplary antigenic inserts include a Gag antigenic insert, a gp41 antigenic insert or a gp120 antigenic insert. Also disclosed are uses of the isolated rubella viral vector, such as to induce an immune response to HIV-1, testing sensitivity to neutralizing antibodies, or screening antiviral drugs (such as protease inhibitors).

Abstract: Disclosed herein are isolated rubella viral vector constructs that include a rubella non-structural protein open reading frame (ORF) with an in-frame deletion, a rubella structural protein ORF, and a heterologous antigenic insert. In one example, the in-frame deletion within the rubella non-structural protein ORF is an in-frame deletion between two NotI restriction enzyme sites. In some examples, the heterologous antigenic insert is positioned within the rubella non-structural protein ORF. In other examples, the heterologous antigenic insert is positioned within the rubella structural protein ORF. Exemplary antigenic inserts include a Gag antigenic insert, a gp41 antigenic insert or a gp120 antigenic insert. Also disclosed are uses of the isolated rubella viral vector, such as to induce an immune response to HIV-1, testing sensitivity to neutralizing antibodies, or screening antiviral drugs (such as protease inhibitors).

Abstract: The present invention is directed to an adjustable belt system for carrying sporting equipment, such as skis, poles, a snowboard, and accessories. The adjustable belt system includes a first elongated strap, a second elongated strap, a first adjustable loop holding member attached to a first end of the first and second elongated straps, and a second adjustable loop holding member attached to a second end of the first and second elongated straps. The first and second elongated straps extend in parallel between the first and second holding members. A method of carrying sporting equipment is also disclosed.

Abstract: The present invention is directed to an adjustable belt for carrying sporting equipment, such as skis, poles and accessories. The adjustable belt includes an elongated flexible strap. First and second holding members are releasably attached to opposite ends of the strap. Each holding member includes a flexible pad having first and second ends. A ridged belt extends outwardly from the first end and a ratcheting buckle is proximate the second end. The ridged belt is received and releasably secured within the ratcheting buckle so that the pad forms a loop having an adjustable diameter by operation of the ratcheting buckle. A method of carrying skiing equipment is also disclosed.