Abstract: A neurostimulator incorporating a novel chip design that uses the principle of redundant signal crossfiring to overcome electronic component mismatch error in general and transistor mismatch error in particular, to yield superior quality neurostimulation signal generation, useful in enhancing the bidirectional human-machine interface in prosthesis operation for the restoration of somatosensation for an amputee.

Abstract: Provided is a Face-aware Offset Calculation (FOC) module and method for facial frame interpolation and enhancement and a face video deblurring system and method using the same. The system comprises: a facial frame enhancement device, including a FOC module, for enhancing a target frame; a facial frame interpolation device, including the FOC module, for interpolating the target frame; and a combination device for combining the enhanced target frame with the interpolated target frame.

Abstract: The present disclosure discloses a wristband nerve stimulator and a use method thereof. The wristband nerve stimulator is small in volume and wearable, and has a waterproof function. As a wristband instrument, the wristband nerve stimulator can perform treatment at any time. Furthermore, the fixed main unit and the band can be quickly mounted and removed, which is convenient to replace the band.

Abstract: A method includes calibrating a cytometric device for analysis of a target cell, by inserting, into the cytometric device, a hydrogel particle. The hydrogel particle has at least one of a background fluorescent property or a spectral property that is substantially similar to the at least one of a background fluorescent property or a spectral property of the target cell. The method also includes measuring at least one property of the hydrogel particle using the cytometric device.

Abstract: Disclosed is an H-bridge control circuit for an electro-stimulation therapeutic instrument for neuromodulation. The H-bridge control circuit includes an H-bridge circuit and a constant current source, where the H-bridge circuit includes a first positive channel metal oxide semiconductor (PMOS) transistor, a second PMOS transistor, a first negative channel metal oxide semiconductor (NMOS) transistor and a second NMOS transistor. Corresponding switching diodes are additionally arranged between the first PMOS transistor and a load and between the second PMOS transistor and the load to avoid an influence of safety of the therapeutic instrument by discharging charges during an interval of stimulation; and moreover, a resistance-capacitance (RC) circuit is additionally arranged between the first PMOS transistor, the second PMOS transistor and a control device such that connection and disconnection of the PMOS transistor can be controlled.

Abstract: Disclosed are a control circuit and control method for an electro-stimulation therapeutic instrument for neuromodulation. The control circuit includes a first switch, a second switch, a third switch, a fourth switch, a first signal end, a second signal end and a constant current source, where a first end of the first switch is connected to a power supply, and a second end of the first switch is connected to the first signal end; a first end of the second switch is connected to the power supply, and a second end of the second switch is connected to the second signal end; a first end of the third switch is connected to the first signal end, and a second end of the third switch is connected to the constant current source; and a first end of the fourth switch is connected to the second signal end.

Abstract: A digital-to-analog converter device including a set of components, each component included in the set of components including a number of unit cells, each unit cell being associated with a unit cell size indicating manufacturing specifications of the unit cell is provided by the present disclosure. The digital-to-analog converter device further includes a plurality of switches, each switch included in the plurality of switches being coupled to a component included in the set of components, and an output electrode coupled to the plurality of switches. The digital-to-analog converter device is configured to output an output signal at the output electrode. A first unit cell size associated with a first unit cell included in the set of components is different than a second unit cell size associated with a second unit cell included in the set of components.

Abstract: Synthetic human cell mimic hydrogel particles and their use in cytometric or coulter device applications are described. The synthetic human cell mimic hydrogel particles described herein are selectively tunable to have at least one optical, volumetric, or capacitance property that is substantially similar to a corresponding optical, volumetric, or capacitance property of the human cell mimic hydrogel particle's natural biological cell counterpart.

Abstract: The present disclosure provides feeder hydrogel particles that can function to support the growth, proliferation, and/or activation of a target cell in culture. The present disclosure also provides methods of culturing target cells with feeder hydrogel particles.

Abstract: A method includes calibrating a cytometric device for analysis of a target cell, by inserting, into the cytometric device, a hydrogel particle. The hydrogel particle has at least one of a background fluorescent property or a spectral property that is substantially similar to the at least one of a background fluorescent property or a spectral property of the target cell. The method also includes measuring at least one property of the hydrogel particle using the cytometric device.

Abstract: Provided herein are hydrogel beads that mimic live, dead, and apoptotic cells. The present disclosure also provides kits and compositions of hydrogel beads. The present disclosure further comprises methods of using the kits, compositions, and hydrogel beads to determine if a target cell sample includes one or more live, dead, or apoptotic cells.

Abstract: Synthetic human cell mimic hydrogel particles and their use in cytometric or coulter device applications are described. The synthetic human cell mimic hydrogel particles described herein are selectively tunable to have at least one optical, volumetric, or capacitance property that is substantially similar to a corresponding optical, volumetric, or capacitance property of the human cell mimic hydrogel particle's natural biological cell counterpart.

Abstract: We describe a Cnx/ERp57 inhibitor for use in the treatment or prevention of cancer.

Abstract: A neurostimulator incorporating a novel chip design that uses the principle of redundant signal crossfiring to overcome electronic component mismatch error in general and transistor mismatch error in particular, to yield superior quality neurostimulation signal generation, useful in enhancing the bidirectional human-machine interface in prosthesis operation for the restoration of somatosensation for an amputee; and an improvement thereof additionally comprising a digital-to-analog converter device, that includes a number of unit cells, each unit cell being associated with a unit cell size indicating manufacturing specifications of the unit cell, and that further includes a plurality of switches, each being coupled to a component, and an output electrode coupled to the plurality of switches, and wherein the digital-to-analog converter device is configured to output an output signal at the output electrode.

Abstract: The method of connection establishment method in data transmission between micro-services in cloud ensures reducing connection complexity between client instances and server instances, increasing the number of connections which helps increase data transmission performance. Besides, the method helps ensure load balancing when server instances change or in time of failure. The proposed method includes the following steps: step 1: data preparation; Step 2: build connection data table; Step 3: select the appropriate connection when receiving a request to send data from the client; step 4: periodically queries the independent service management, updating the current state of the server instances.

Abstract: Synthetic human cell mimic hydrogel particles and their use in cytometric or coulter device applications are described. The synthetic human cell mimic hydrogel particles described herein are selectively tunable to have at least one optical, volumetric, or capacitance property that is substantially similar to a corresponding optical, volumetric, or capacitance property of the human cell mimic hydrogel particle's natural biological cell counterpart.

Abstract: Systems, devices, and methods redact one or more light-emitting screens in data recorded on a recording device. The redaction may include receiving recorded data comprising a plurality of pixel values. The redaction may include detecting one or more light-emitting screens in the received image. The redaction may include redacting a subset of the pixel values from the recorded associated with the one or more detected light-emitting screens. The redaction may be commonly applied to multiple frames of recorded data through the use of a unique identifier assigned to a same detected light-emitting screen. A same light-emitting screen may be tracked across multiple non-sequential or sequential frames and assigned a same unique identifier.

Abstract: The present disclosure provides feeder hydrogel particles that can function to support the growth, proliferation, and/or activation of a target cell in culture. The present disclosure also provides methods of culturing target cells with feeder hydrogel particles.

Abstract: We describe a Cnx/ERp57 inhibitor for use in the treatment or prevention of cancer.

Abstract: A method includes calibrating a cytometric device for analysis of a target cell, by inserting, into the cytometric device, a hydrogel particle. The hydrogel particle has at least one of a background fluorescent property or a spectral property that is substantially similar to the at least one of a background fluorescent property or a spectral property of the target cell. The method also includes measuring at least one property of the hydrogel particle using the cytometric device.