Patents by Inventor Anil K. Saksena

Anil K. Saksena has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sulfur compounds as inhibitors of hepatitis C virus NS3 serine protease
    Patent number: 8067379
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Grant
    Filed: February 24, 2005
    Date of Patent: November 29, 2011
    Assignee: Schering Corporation
    Inventors: Frank Bennett, Raymond G. Lovey, Yuhua Huang, Siska Hendrata, Anil K. Saksena, Stephane L. Bogen, Yi-Tsung Liu, F. George Njoroge, Srikanth Venkatraman, Kevin X. Chen, Mousumi Sannigrahi, Ashok Arasappan, Viyyoor M. Girijavallabhan, Francisco Velazquez, Latha G. Nair
  • NOVEL PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS
    Publication number: 20110117057
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: December 20, 2010
    Publication date: May 19, 2011
    Applicants: SCHERING CORPORATION, DENDREON CORPORATION
    Inventors: Anil K. Saksena, Viyyoor Moopil Girijavallabhan, Raymond G. Lovey, Edwin Jao, Frank Bennett, Jinping L. McCormick, Haiyan Wang, Russell E. Pike, Stephane L. Bogen, Tin-Yau Chan, Yi-Tsung Liu, Zhaoning Zhu, F. George Njoroge, Ashok Arasappan, Tejal Parekh, Ashit K. Ganguly, Kevin X. Chen, Srikanth Venkatraman, Henry A. Vaccaro, Patrick A. Pinto, Bama Santhanam, Scott Jeffrey Kemp, Odile Esther Levy, Marguerita Lim-Wilby, Susan Y. Tamura, Wanli Wu, Siska Hendrata, Yuhua Huang
  • 17?-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
    Patent number: 7432268
    Abstract: There are disclosed compounds of the formula (I): prodrugs thereof, or pharmaceutically acceptable salts of the compounds or of said prodrugs which are useful as inhibitors of Type 3 17?-Hydroxysteroid Dehydrogenase. Also disclosed are pharmaceutical compositions containing said compounds and their use for the treatment or prevention of androgen dependent diseases.
    Type: Grant
    Filed: November 14, 2005
    Date of Patent: October 7, 2008
    Assignee: Schering Corporation
    Inventors: Timothy Guzi, Kamil Paruch, Alan Mallams, Jocelyn D. Rivera, Ronald J. Doll, Viyyoor M. Girijavallabhan, Jonathan A. Pachter, Yi-Tsung Liu, Anil K. Saksena
  • Compounds as inhibitors of hepatitis C virus NS3 serine protease
    Patent number: 7425576
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: September 16, 2008
    Assignee: Schering Corporation
    Inventors: Ashok Arasappan, F. George Njoroge, Angela I. Padilla-Acevedo, Kevin X. Chen, Frank Bennett, Mousumi Sannigrahi, Stephane L. Bogen, Srikanth Venkatraman, Edwin E. Jao, Anil K. Saksena, Viyyoor M. Girijavallabhan
  • Inhibitors of hepatitis C virus NS3 protease
    Patent number: 7423058
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: September 9, 2008
    Assignee: Schering Corporation
    Inventors: Stephane L. Bogen, Weidong Pan, Sumei Ruan, Kevin X. Chen, Ashok Arasappan, Srikanth Venkatraman, Latha G. Nair, Mousumi Sannigrahi, Frank Bennett, Anil K. Saksena, F. George Njoroge, Viyyoor M. Girijavallabhan
  • Peptides as NS3-serine protease inhibitors of hepatitis C virus
    Patent number: 7244721
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Grant
    Filed: January 18, 2002
    Date of Patent: July 17, 2007
    Assignees: Schering Corporation, Dendreon Corporation
    Inventors: Anil K. Saksena, Viyyoor Moopil Girijavallabhan, Raymond G. Lovey, Edwin Jao, Frank Bennett, Jinping L. Mc Cormick, Haiyan Wang, Russell E. Pike, Stephane L. Bogen, Tin-Yau Chan, Yi-Tsung Liu, Zhaoning Zhu, F. George Njoroge, Ashok Arasappan, Tejal Parekh, Ashit K. Ganguly, Kevin X. Chen, Srikanth Venkatraman, Henry A. Vaccaro, Patrick A. Pinto, Bama Santhanam, Scott Jeffrey Kemp, Odile Esther Levy, Marguerita Lim-Wilby, Susan Y. Tamura, Wanli Wu, Siska Hendrata, Yuhua Huang, Jesse K. Wong, Latha G. Nair
  • Inhibitors of hepatitis C virus NS3 protease
    Patent number: 7205330
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Grant
    Filed: February 24, 2005
    Date of Patent: April 17, 2007
    Assignee: Schering Corporation
    Inventors: Stephane L. Bogen, Weidong Pan, Sumei Ruan, Kevin X. Chen, Ashok Arasappan, Srikanth Venkatraman, Latha G. Nair, Mousumi Sannigrahi, Frank Bennett, Anil K. Saksena, F. George Njoroge, Viyyoor M. Girijavallabhan
  • Compounds as inhibitors of hepatitis C virus NS3 serine protease
    Patent number: 7186747
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Grant
    Filed: February 24, 2005
    Date of Patent: March 6, 2007
    Assignee: Schering Corporation
    Inventors: Ashok Arasappan, F. George Njoroge, Angela I. Padilla-Acevedo, Kevin X. Chen, Frank Bennett, Mousumi Sannigrahi, Stephane L. Bogen, Srikanth Venkatraman, Edwin Jao, Anil K. Saksena, Viyyoor M. Girijavallabhan
  • Peptides as NS3-serine protease inhibitors of hepatitis C virus
    Patent number: 7169760
    Abstract: The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Grant
    Filed: July 19, 2001
    Date of Patent: January 30, 2007
    Assignees: Schering Corporation, Dendreon Corporation
    Inventors: Anil K. Saksena, Viyyoor Moopil Girijavallabhan, Stephane L. Bogen, Raymond G. Lovey, Edwin Jao, Frank Bennett, Jinping L. Mc Cormick, Haiyan Wang, Russell E. Pike, Yi-Tsung Liu, Tin-Yau Chan, Zhaoning Zhu, Ashok Arasappan, Kevin X. Chen, Srinkanth Venkatraman, Tejal Parekh, Patrick A. Pinto, Bama Santhanam, F. George Njoroge, Ashit K. Ganguly, Henry A. Vaccaro, Scott Jeffrey Kemp, Odile Esther Levy, Marguerita Lim-Wilby, Susan Y. Tamura
  • 17 ?-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
    Patent number: 7138396
    Abstract: There are disclosed compounds of the formula (I): prodrugs thereof, or pharmaceutically acceptable salts of the compounds or of said prodrugs which are useful as inhibitors of Type 3 17?-Hydroxysteroid Dehydrogenase. Also disclosed are pharmaceutical compositions containing said compounds and their use for the treatment or prevention of androgen dependent diseases.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: November 21, 2006
    Assignee: Schering Corporation
    Inventors: Timothy J. Guzi, Kamil Paruch, Alan K. Mallams, Jocelyn D. Rivera, Ronald J. Doll, Viyyoor M. Girijavallabhan, Jonathan A. Pachter, Yi-Tsung Liu, Anil K. Saksena
  • Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection
    Patent number: 7115578
    Abstract: Ribavirin derivatives represented by the formula V, pharmaceutical compositions containing them as well as the use of the ribavirin derivatives represented by the formula V for the preparation of a medicament for the treatment of susceptible viral infections, for example, chronic hepatitis C infections administrating, the ribavirin derivatives being represented by formula V are disclosed.
    Type: Grant
    Filed: July 6, 2004
    Date of Patent: October 3, 2006
    Assignee: Schering Corporation
    Inventors: Ashit K. Ganguly, Jinping McCormick, Raymond G. Lovey, Frank Bennett, Anil K. Saksena, Viyyoor M. Girijavallabhan
  • Peptides as NS3-serine protease inhibitors of hepatitis C virus
    Patent number: 7012066
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Grant
    Filed: July 19, 2001
    Date of Patent: March 14, 2006
    Assignees: Schering Corporation, Dendreon Corporation
    Inventors: Anil K. Saksena, Viyyoor Moopil Girijavallabhan, Raymond G. Lovey, Edwin Jao, Frank Bennett, Jinping L. Mc Cormick, Haiyan Wang, Russell E. Pike, Stephane L. Bogen, Tin-Yau Chan, Yi-Tsung Liu, Zhaoning Zhu, F. George Njoroge, Ashok Arasappan, Tejal Parekh, Ashit K. Ganguly, Kevin X. Chen, Srikanth Venkatraman, Henry A. Vaccaro, Patrick A. Pinto, Bama Santhanam, Scott Jeffrey Kemp, Odile Esther Levy, Marguerita Lim-Wilby, Susan Y. Tamura, Wanli Wu, Siska Hendrata, Yuhua Huang
  • Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection
    Patent number: 6924270
    Abstract: Ribavirin derivatives represented by the formula II, pharmaceutical compositions containing them as well as methods of using the ribavirin derivatives represented by the formula II for the treatment of susceptible viral infections, for example, chronic hepatitis C infections administrating, the ribavirin derivatives being represented by formula II are disclosed.
    Type: Grant
    Filed: April 18, 2001
    Date of Patent: August 2, 2005
    Assignee: Schering Corporation
    Inventors: Ashit K. Ganguly, Jinping Mc Cormick, Raymond G. Lovey, Frank Bennett, Anil K. Saksena, Viyyoor M. Girijavallabhan
  • 17?-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
    Patent number: 6903102
    Abstract: There are disclosed compounds of the formula (I): prodrugs thereof, or pharmaceutically acceptable salts of the compounds or of said prodrugs which are useful as inhibitors of Type 3 17?-Hydroxysteroid Dehydrogenase. Also disclosed are pharmaceutical compositions containing said compounds and their use for the treatment or prevention of androgen dependent diseases.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: June 7, 2005
    Assignee: Schering Corporation
    Inventors: Timothy J. Guzi, Kamil Paruch, Alan K. Mallams, Jocelyn D. Rivera, Ronald J. Doll, Viyyoor M. Girijavallabhan, Jonathan A. Pachter, Yi-Tsung Liu, Anil K. Saksena
  • Compounds as NS3-serine protease inhibitors of hepatitis C virus
    Patent number: 6894072
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Grant
    Filed: January 21, 2003
    Date of Patent: May 17, 2005
    Assignee: Schering Corporation
    Inventors: Ashok Arasappan, Frank Bennett, Stephane L. Bogen, Kevin X. Chen, Edwin Jao, Yi-Tsung Liu, Raymond G. Lovey, Vincent S. Madison, Latha G. Nair, F. George Njoroge, Anil K. Saksena, Mousumi Sannigrahi, Srikanth Venkatraman, Viyyoor M. Girijavallabhan
  • Novel peptides as NS3-serine protease inhibitors of hepatitis C virus
    Publication number: 20040254117
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: July 19, 2001
    Publication date: December 16, 2004
    Inventors: Anil K. Saksena, Viyyoor Moopil Girijavallabhan, Raymond G. Lovey, Edwin Jao, Frank Bennett, Jinping L. McCormick, Haiyan Wang, Russell E. Pike, Stephane L. Bogen, Tin-Yau Chan, Yi-Tsung Liu, Zhaoning Zhu, F. George Njoroge, Ashok Arasappan, Tejal Parekh, Ashit K. Ganguly, Kevin X. Chen, Srikanth Venkatraman, Henry A. Vaccaro, Patrick A. Pinto, Bama Santhanam, Scott Jeffrey Kemp, Odile Esther Levy, Marguerita Lim-Wilby, Susan Y. Tamura, Wanli Wu, Siska Hendrata, Yuhua Huang
  • Peptides as NS3-serine protease inhibitors of hepatitis C virus
    Patent number: 6800434
    Abstract: The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such peptides as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Grant
    Filed: July 19, 2001
    Date of Patent: October 5, 2004
    Assignees: Schering Corporation, Dendreon Corporation
    Inventors: Anil K. Saksena, Viyyoor Moopil Girijavallabhan, Raymond G. Lovey, Edwin Jao, Frank Bennett, Jinping L. McCormick, Haiyan Wang, Russell E. Pike, Stephane L. Bogen, Yi-Tsung Liu, Ashok Arasappan, Tejal Parekh, Patrick A. Pinto, F. George Njoroge, Ashit K. Ganguly, Terence K. Brunck, Scott Jeffrey Kemp, Odile Esther Levy, Marguerita Lim-Wilby
  • Compounds useful for inhibition of farnesyl protein transferase
    Publication number: 20040157872
    Abstract: Novel compounds of the formula: 1
    Type: Application
    Filed: February 9, 2004
    Publication date: August 12, 2004
    Inventors: Alan B. Cooper, Ronald J. Doll, Anil K. Saksena, Viyyoor M. Girijavallabhan
  • 17 Beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
    Publication number: 20040132736
    Abstract: There are disclosed compounds of the formula (I): 1
    Type: Application
    Filed: September 5, 2002
    Publication date: July 8, 2004
    Applicant: Schering Corporation
    Inventors: Timothy J. Guzi, Kamil Paruch, Alan K. Mallams, Jocelyn D. Rivera, Ronald J. Doll, Viyyoor M. Girijavallabhan, Jonathan A. Pachter, Yi-Tsung Liu, Anil K. Saksena
  • Peptides as NS3-serine protease inhibitors of hepatitis C virus
    Patent number: RE43298
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Grant
    Filed: April 22, 2011
    Date of Patent: April 3, 2012
    Assignees: Schering Corporation, Dendreon Corporation
    Inventors: Anil K. Saksena, Viyyoor Moopil Girijavallabhan, Raymond G. Lovey, Edwin Jao, Frank Bennett, Jinping L. McCormick, Haiyan Wang, Russell E. Pike, Stephane L. Bogen, Tin-Yau Chan, Yi-Tsung Liu, Zhaoning Zhu, F. George Njoroge, Ashok Arasappan, Tejal Parekh, Ashit K. Ganguly, Kevin X. Chen, Srikanth Venkatraman, Henry M. Vaccaro, Patrick A. Pinto, Bama Santhanam, Scott Jeffrey Kemp, Odile Esther Levy, Marguerita Lim-Wilby, Susan Y. Tamura, Wanli Wu, Siska Hendrata, Yuhua Huang